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This review is about statistical genetics, an interdisciplinary topic between statistical physics and population biology. The focus is on the phase of quasi-linkage equilibrium (QLE). Our goals here are to clarify under which conditions the…

Populations and Evolution · Quantitative Biology 2023-04-07 Vito Dichio , Hong-Li Zeng , Erik Aurell

Within the rigorous axiomatic framework for the description of quantum mechanical systems with a large number of degrees of freedom, we show that the nonequilibrium steady state, constructed in the quasifree fermionic system corresponding…

Mathematical Physics · Physics 2016-09-22 Walter H. Aschbacher

Phase separation routinely occurs in both living and synthetic systems. These phases are often complex and distinguished by features including crystallinity, nematic order, and a host of other nonconserved order parameters. For systems at…

Statistical Mechanics · Physics 2025-12-08 Daniel Evans , Ahmad K. Omar

Traditionally, phase transitions are defined in the thermodynamic limit only. We propose a new formulation of equilibrium thermo-dynamics that is based entirely on mechanics and reflects just the {\em geometry and topology} of the N-body…

Statistical Mechanics · Physics 2009-10-31 D. H. E. Gross

We develop a quasilinear theory of the Vlasov equation in order to describe the approach of systems with long-range interactions to quasi-stationary states. We derive a diffusion equation governing the evolution of the velocity distribution…

Statistical Mechanics · Physics 2017-11-27 Alessandro Campa , Pierre-Henri Chavanis

The population dynamics and stability of ecosystems of interacting species is studied from the perspective of non-equilibrium thermodynamics by assuming that species, through their biotic and abiotic interactions, are units of entropy…

Biological Physics · Physics 2007-05-23 Karo Michaelian

We study the off-equilibrium behavior of systems with short-range interactions driven across a thermal first-order transition, where the dynamics is exponentially slow. We consider a dynamics that starts in the high-T phase at time t =…

Statistical Mechanics · Physics 2017-01-25 Andrea Pelissetto , Ettore Vicari

We study a mechanism for reliable switching in biomolecular signal-transduction cascades. Steady bistable states are created by system-size cooperative effects in populations of proteins, in spite of the fact that the phosphorylation-state…

Subcellular Processes · Quantitative Biology 2015-05-30 Eric Smith , Supriya Krishnamurthy , Walter Fontana , David Krakauer

The phase of Quasi-Linkage Equilibrium (QLE) in evolutionary populations is analogous to the thermal equilibrium state in statistical mechanics, a concept pioneered by Kimura in 1965 for two-locus two-allele models. QLE describes a…

Populations and Evolution · Quantitative Biology 2026-05-22 Yu-Han Huang , Bastien Dumont , Hong-Li Zeng , John Barton , Erik Aurell

We establish sufficient conditions for exponential convergence to a unique quasi-stationary distribution in the total variation norm. These conditions also ensure the existence and exponential ergodicity of the Q-process, the process…

Probability · Mathematics 2023-08-01 Aurélien Velleret

We propose a stochastic model for evolution. Births and deaths of species occur with constant probabilities. Each new species is associated with a fitness sampled from the uniform distribution on [0,1]. Every time there is a death event…

Probability · Mathematics 2010-11-09 Herve Guiol , Fabio P. Machado , Rinaldo B. Schinazi

A branching random walk in presence of an absorbing wall moving at a constant velocity $v$ undergoes a phase transition as the velocity $v$ of the wall varies. Below the critical velocity $v_c$, the population has a non-zero survival…

Statistical Mechanics · Physics 2008-02-12 Damien Simon , Bernard Derrida

We briefly review some equilibrium and nonequilibrium properties of systems with long-range interactions. Such systems, which are characterized by a potential that weakly decays at large distances, have striking properties at equilibrium,…

Statistical Mechanics · Physics 2009-11-13 Stefano Ruffo

Hamiltonian systems with long-range interactions give rise to long lived out of equilibrium macroscopic states, so-called quasi-stationary states. We show here that, in a suitably generalized form, this result remains valid for many such…

Statistical Mechanics · Physics 2015-06-17 Michael Joyce , Jules Morand , François Sicard , Pascal Viot

Inspired by biological systems, we introduce a general framework for quasi-static shape control of human-scale structures under slowly varying external actions or requirements. In this setting, shape control aims to traverse the stable…

Soft Condensed Matter · Physics 2025-09-17 Eszter Fehér , András Árpád Sipos , Péter Várkonyi

We extend a technique of approximation of the long-term behavior of a supercritical stochastic epidemic model, using the WKB approximation and a Hamiltonian phase space, to the subcritical case. The limiting behavior of the model and…

Populations and Evolution · Quantitative Biology 2017-07-04 Lee Worden , Ira B. Schwartz , Simone Bianco , Sarah F. Ackley , Thomas M. Lietman , Travis C. Porco

Under many circumstances many soft and hard materials are present in a puzzling wealth of non-equilibrium amorphous states, whose properties are not stationary and depend on preparation. They are often summarized in unconventional "phase…

Soft Condensed Matter · Physics 2021-04-20 Jesús Benigno Zepeda-López , Magdaleno Medina-Noyola

Biological systems are modular, and this modularity evolves over time and in different environments. A number of observations have been made of increased modularity in biological systems under increased environmental pressure. We here…

Populations and Evolution · Quantitative Biology 2015-01-07 Jeong-Man Park , Liang Ren Niestemski , Michael W. Deem

The dynamics of the approach to equilibrium of the hydrogen atom is investigated numerically through a Monte Carlo procedure. We show that, before approaching ionization, the hydrogen atom may live in a quasi-equilibrium state,…

Statistical Mechanics · Physics 2007-05-23 N. M. Oliveira-Neto , E. M. F. Curado , F. D. Nobre , M. A. Rego-Monteiro

Phenotypically structured equations arise in population biology to describe the interaction of species with their environment that brings the nutrients. This interaction usually leads to selection of the fittest individuals. Models used in…

Analysis of PDEs · Mathematics 2015-06-18 Alexander Lorz , Benoit Perthame