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Medical multimodal representation learning aims to integrate heterogeneous clinical data into unified patient representations to support predictive modeling, which remains an essential yet challenging task in the medical data mining…

Machine Learning · Computer Science 2025-09-09 Xiaoguang Zhu , Lianlong Sun , Yang Liu , Pengyi Jiang , Uma Srivatsa , Nipavan Chiamvimonvat , Vladimir Filkov

Breast cancer is a major concern for women's health globally, with axillary lymph node (ALN) metastasis identification being critical for prognosis evaluation and treatment guidance. This paper presents a deep learning (DL) classification…

Image and Video Processing · Electrical Eng. & Systems 2023-10-09 Glejdis Shkëmbi , Johanna P. Müller , Zhe Li , Katharina Breininger , Peter Schüffler , Bernhard Kainz

Accurate survival prediction in Non-Small Cell Lung Cancer (NSCLC) requires integrating clinical, radiological, and histopathological data. Multimodal Deep Learning (MDL) can improve precision prognosis, but small cohorts and missing…

Healthcare applications are inherently multimodal, benefiting greatly from the integration of diverse data sources. However, the modalities available in clinical settings can vary across different locations and patients. A key area that…

Computer Vision and Pattern Recognition · Computer Science 2025-09-04 Mohammed Amer , Mohamed A. Suliman , Tu Bui , Nuria Garcia , Serban Georgescu

In real-world clinical settings, magnetic resonance imaging (MRI) frequently suffers from missing modalities due to equipment variability or patient cooperation issues, which can significantly affect model performance. To address this…

Computer Vision and Pattern Recognition · Computer Science 2025-09-23 Zhejia Zhang , Junjie Wang , Le Zhang

Assessing the pre-operative risk of lymph node metastases in endometrial cancer patients is a complex and challenging task. In principle, machine learning and deep learning models are flexible and expressive enough to capture the dynamics…

Artificial Intelligence · Computer Science 2023-05-18 Alessio Zanga , Alice Bernasconi , Peter J. F. Lucas , Hanny Pijnenborg , Casper Reijnen , Marco Scutari , Fabio Stella

Objectives: To develop and validate a deep learning (DL)-based primary tumor biopsy signature for predicting axillary lymph node (ALN) metastasis preoperatively in early breast cancer (EBC) patients with clinically negative ALN. Methods: A…

Image and Video Processing · Electrical Eng. & Systems 2022-06-09 Feng Xu , Chuang Zhu , Wenqi Tang , Ying Wang , Yu Zhang , Jie Li , Hongchuan Jiang , Zhongyue Shi , Jun Liu , Mulan Jin

In many histopathology tasks, sample classification depends on morphological details in tissue or single cells that are only visible at the highest magnification. For a pathologist, this implies tedious zooming in and out, while for a…

Computer Vision and Pattern Recognition · Computer Science 2023-03-03 Ario Sadafi , Nassir Navab , Carsten Marr

Managing fluid balance in dialysis patients is crucial, as improper management can lead to severe complications. In this paper, we propose a multimodal approach that integrates visual features from lung ultrasound images with clinical data…

Image and Video Processing · Electrical Eng. & Systems 2024-10-04 Tianqi Yang , Nantheera Anantrasirichai , Oktay Karakuş , Marco Allinovi , Alin Achim

Liver cancer is one of the most common cancers worldwide. Due to inconspicuous texture changes of liver tumor, contrast-enhanced computed tomography (CT) imaging is effective for the diagnosis of liver cancer. In this paper, we focus on…

Image and Video Processing · Electrical Eng. & Systems 2021-07-22 Yao Zhang , Jiawei Yang , Jiang Tian , Zhongchao Shi , Cheng Zhong , Yang Zhang , Zhiqiang He

Fusing multi-modal data can improve the performance of deep learning models. However, missing modalities are common for medical data due to patients' specificity, which is detrimental to the performance of multi-modal models in…

Image and Video Processing · Electrical Eng. & Systems 2023-09-28 Muyu Wang , Shiyu Fan , Yichen Li , Hui Chen

In multi-modal learning, some modalities are more influential than others, and their absence can have a significant impact on classification/segmentation accuracy. Addressing this challenge, we propose a novel approach called Meta-learned…

Computer Vision and Pattern Recognition · Computer Science 2025-08-27 Hu Wang , Salma Hassan , Yuyuan Liu , Congbo Ma , Yuanhong Chen , Qing Li , Jiahui Geng , Bingjie Wang , Yu Tian , Yutong Xie , Jodie Avery , Louise Hull , Ian Reid , Mohammad Yaqub , Gustavo Carneiro

Accurate brain tumor segmentation is essential for preoperative evaluation and personalized treatment. Multi-modal MRI is widely used due to its ability to capture complementary tumor features across different sequences. However, in…

Computer Vision and Pattern Recognition · Computer Science 2025-09-19 Shenghao Zhu , Yifei Chen , Weihong Chen , Shuo Jiang , Guanyu Zhou , Yuanhan Wang , Feiwei Qin , Changmiao Wang , Qiyuan Tian

In medical vision, different imaging modalities provide complementary information. However, in practice, not all modalities may be available during inference or even training. Previous approaches, e.g., knowledge distillation or image…

Computer Vision and Pattern Recognition · Computer Science 2023-08-23 Aishik Konwer , Xiaoling Hu , Joseph Bae , Xuan Xu , Chao Chen , Prateek Prasanna

Esophageal cancer is one of the most common types of cancer worldwide and ranks sixth in cancer-related mortality. Accurate computer-assisted diagnosis of cancer progression can help physicians effectively customize personalized treatment…

Image and Video Processing · Electrical Eng. & Systems 2024-05-17 Chengyu Wu , Chengkai Wang , Yaqi Wang , Huiyu Zhou , Yatao Zhang , Qifeng Wang , Shuai Wang

The problem of missing modalities is both critical and non-trivial to be handled in multi-modal models. It is common for multi-modal tasks that certain modalities contribute more compared to other modalities, and if those important…

Computer Vision and Pattern Recognition · Computer Science 2025-03-17 Hu Wang , Congbo Ma , Jianpeng Zhang , Yuan Zhang , Jodie Avery , Louise Hull , Gustavo Carneiro

Malignant brain tumors have become an aggressive and dangerous disease that leads to death worldwide.Multi-modal MRI data is crucial for accurate brain tumor segmentation, but missing modalities common in clinical practice can severely…

Methodology · Statistics 2025-07-11 Guoyan Liang , Qin Zhou , Jingyuan Chen , Bingcang Huang , Kai Chen , Lin Gu , Zhe Wang , Sai Wu , Chang Yao

Digitization of histopathology slides has led to several advances, from easy data sharing and collaborations to the development of digital diagnostic tools. Deep learning (DL) methods for classification and detection have shown great…

Image and Video Processing · Electrical Eng. & Systems 2020-05-25 Apostolia Tsirikoglou , Karin Stacke , Gabriel Eilertsen , Martin Lindvall , Jonas Unger

The evaluation of lymph node metastases plays a crucial role in achieving precise cancer staging, influencing subsequent decisions regarding treatment options. Lymph node detection poses challenges due to the presence of unclear boundaries…

Computer Vision and Pattern Recognition · Computer Science 2024-06-07 Sofija Engelson , Jan Ehrhardt , Timo Kepp , Joshua Niemeijer , Heinz Handels

Integrating artificial intelligence (AI) with healthcare data is rapidly transforming medical diagnostics and driving progress toward precision medicine. However, effectively leveraging multimodal data, particularly digital pathology whole…

Image and Video Processing · Electrical Eng. & Systems 2025-12-15 Areej Alsaafin , Abubakr Shafique , Saghir Alfasly , Krishna R. Kalari , H. R. Tizhoosh
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