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Assessing the presence of potentially malignant lymph nodes aids in estimating cancer progression, and identifying surrounding benign lymph nodes can assist in determining potential metastatic pathways for cancer. For quantitative analysis,…
Multimodal models often over-rely on dominant modalities, failing to achieve optimal performance. While prior work focuses on modifying training objectives or optimization procedures, data-centric solutions remain underexplored. We propose…
Advances in medical imaging and deep learning have propelled progress in whole slide image (WSI) analysis, with multiple instance learning (MIL) showing promise for efficient and accurate diagnostics. However, conventional MIL models often…
Medical image segmentation of tumors and organs at risk is a time-consuming yet critical process in the clinic that utilizes multi-modality imaging (e.g, different acquisitions, data types, and sequences) to increase segmentation precision.…
Histopathology remains the gold standard for cancer diagnosis and prognosis. With the advent of transcriptome profiling, multi-modal learning combining transcriptomics with histology offers more comprehensive information. However, existing…
Clinical notes contain rich patient information, such as diagnoses or medications, making them valuable for patient representation learning. Recent advances in large language models have further improved the ability to extract meaningful…
Immunohistochemical (IHC) biomarker prediction benefits from multi-modal data fusion analysis. However, the simultaneous acquisition of multi-modal data, such as genomic and pathological information, is often challenging due to cost or…
The diagnosis of the presence of metastatic lymph nodes from abdominal computed tomography (CT) scans is an essential task performed by radiologists to guide radiation and chemotherapy treatment. State-of-the-art deep learning classifiers…
Recently, various deep learning methods have shown significant successes in medical image analysis, especially in the detection of cancer metastases in hematoxylin and eosin (H&E) stained whole-slide images (WSIs). However, in order to…
Multimodal machine learning integrating histopathology and molecular data shows promise for cancer prognostication. We systematically reviewed studies combining whole slide images (WSIs) and high-throughput omics to predict overall…
Multimodal Magnetic Resonance Imaging (MRI) provides essential complementary information for analyzing brain tumor subregions. While methods using four common MRI modalities for automatic segmentation have shown success, they often face…
Multimodal networks have demonstrated remarkable performance improvements over their unimodal counterparts. Existing multimodal networks are designed in a multi-branch fashion that, due to the reliance on fusion strategies, exhibit…
Pathological lymph node delineation is crucial in cancer diagnosis, progression assessment, and treatment planning. The MICCAI 2023 Lymph Node Quantification Challenge published the first public dataset for pathological lymph node…
Multimodal deep learning has shown strong potential in medical applications by integrating heterogeneous data sources such as medical images and structured clinical variables. However, most existing approaches implicitly assume complete…
The scarcity of labeled data is a major bottleneck for developing accurate and robust deep learning-based models for histopathology applications. The problem is notably prominent for the task of metastasis detection in lymph nodes, due to…
Recent advances in histopathology vision-language foundation models (VLFMs) have shown promise in addressing data scarcity for whole slide image (WSI) classification via zero-shot adaptation. However, these methods remain outperformed by…
Annotating cancerous regions in whole-slide images (WSIs) of pathology samples plays a critical role in clinical diagnosis, biomedical research, and machine learning algorithms development. However, generating exhaustive and accurate…
A method has been developed for the analysis of images of sentinel lymph nodes generated by a spectral scanning device. The aim is to classify the nodes, excised during surgery for breast cancer, as normal or metastatic. The data from one…
Whole slide images (WSIs) are gigapixel-scale digital images of H\&E-stained tissue samples widely used in pathology. The substantial size and complexity of WSIs pose unique analytical challenges. Multiple Instance Learning (MIL) has…
Self-supervised learning has greatly facilitated medical image analysis by suppressing the training data requirement for real-world applications. Current paradigms predominantly rely on self-supervision within uni-modal image data, thereby…