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We use coarse-grained molecular dynamics simulations to study the motility of a 2D vesicle containing self-propelled rods, as a function of the vesicle bending rigidity and the number density, length, and activity of the enclosed rods.…

Soft Condensed Matter · Physics 2023-03-29 Sarvesh Uplap , Michael F. Hagan , Aparna Baskaran

The slime mould Physarum polycephalum has been used in developing unconventional computing devices for in which the slime mould played a role of a sensing, actuating, and computing device. These devices treated the slime mould rather as an…

Self-regulation of living tissue as an example of self-organization phenomena in active fractal systems of biological, ecological, and social nature is under consideration. The characteristic feature of these systems is the absence of any…

Tissues and Organs · Quantitative Biology 2008-12-02 Wassily Lubashevsky , Ihor Lubashevsky , Reinhard Mahnke

Life in complex systems, such as cities and organisms, comes to a standstill when global coordination of mass, energy, and information flows is disrupted. Global coordination is no less important in single cells, especially in large oocytes…

For a wide range of modern soft functional materials the selective transport of sub-nanometer-sized molecules (`penetrants') through a stimuli-responsive polymeric membrane is key to the desired function. In this study, we investigate the…

Soft Condensed Matter · Physics 2018-08-28 Matej Kanduc , Won Kyu Kim , Rafael Roa , Joachim Dzubiella

Motor-driven cytoskeletal remodeling in cellular systems can often be accompanied by a diffusive-like effect at local scales, but distinguishing the contributions of the ordering process, such as active contraction of a network, from this…

Biological Physics · Physics 2024-08-22 Soichi Hirokawa , Heun Jin Lee , Rachel A Banks , Ana I Duarte , Bibi Najma , Matt Thomson , Rob Phillips

The cell cytoskeleton is a striking example of "active" medium driven out-of-equilibrium by ATP hydrolysis. Such activity has been shown recently to have a spectacular impact on the mechanical and rheological properties of the cellular…

Statistical Mechanics · Physics 2015-05-13 C. Loverdo , O. Benichou , M. Moreau , R. Voituriez

The symmetry breaking of the actin network from radial to longitudinal symmetry has been identified as the major mechanism for keratocytes (fish cells) motility on solid substrate. For strong friction coefficient, the two dimensional actin…

Soft Condensed Matter · Physics 2011-02-16 M. Ben Amar , O. V. Manyuhina , G. Napoli

In cells, cytoskeletal filament networks are responsible for cell movement, growth, and division. Filaments in the cytoskeleton are driven and organized by crosslinking molecular motors. In reconstituted cytoskeletal systems, motor activity…

Coherent, large scale dynamics in many nonequilibrium physical, biological, or information transport networks are driven by small-scale local energy input. Here, we introduce and explore an analytically tractable nonlinear model for…

Biological Physics · Physics 2017-07-19 Aden Forrow , Francis G. Woodhouse , Jörn Dunkel

While the collective motion of active particles has been studied extensively, effective strategies to navigate particle swarms without external guidance remain elusive. We introduce a method to control the trajectories of two-dimensional…

Soft Condensed Matter · Physics 2023-08-28 Sophie Y. Lee , Philipp W. A. Schönhöfer , Sharon C. Glotzer

Collective motion in animal groups provide examples of emergent, decentralised coordination. Here, we examine a bottom-up model of collective behavior based on Future State Maximisation (FSM). In this model agents seek to maximise the…

Physics and Society · Physics 2026-01-22 Sam Turley , Matthew Turner

Recent experiments on active materials, such as dense bacterial suspensions and microtubule-kinesin motor mixtures, show a promising potential for achieving self-sustained flows. However, to develop active microfluidics it is necessary to…

Soft Condensed Matter · Physics 2019-01-23 Santhan Chandragiri , Amin Doostmohammadi , Julia M Yeomans , Sumesh P Thampi

Semiflexible polymers such as filamentous actin play a vital role in the mechanical behavior of cells, yet the basic properties of cross-linked F-actin networks remain poorly understood. To address this issue, we have performed numerical…

Soft Condensed Matter · Physics 2009-11-10 D. A. Head , A. J. Levine , F. C. MacKintosh

We use nonequilibrium molecular dynamics simulations to verify recent tube-model predictions that associative polymer networks exhibit broad stretch fluctuations during elongational flow. Simulations further show that these fluctuating…

Soft Condensed Matter · Physics 2025-04-11 Songyue Liu , Thomas C. O'Connor

Inspired by recent experiments of cells accumulating on anisotropic substrates, we study a two-dimensional, compressible, isotropic, active fluid in the presence of anisotropic friction. We find that regions of anisotropic friction that are…

Soft Condensed Matter · Physics 2026-03-04 Cody D. Schimming , Brian A. Camley

We investigate the capability of an active body (master) to manipulate a passive object (slave) purely via contactless flow-mediated mechanisms, motivated by potential applications in microfluidic devices and medicine (drug delivery…

Fluid Dynamics · Physics 2019-10-23 Tejaswin Parthasarathy , Fan Kiat Chan , Mattia Gazzola

Self organization mechanisms are essential for the cytoskeleton to adapt to the requirements of living cells. They rely on the intricate interplay of cytoskeletal filaments, crosslinking proteins and molecular motors. Here we present an in…

Biological Physics · Physics 2015-05-28 Simone Köhler , Volker Schaller , Andreas R. Bausch

Leaf venation is a pervasive example of a complex biological network, endowing leaves with a transport system and mechanical resilience. Transport networks optimized for efficiency have been shown to be trees, i.e. loopless. However,…

Biological Physics · Physics 2015-05-13 Eleni Katifori , Gergely J. Szöllősi , Marcelo O. Magnasco

Distribution networks -- from vasculature to urban transportation systems -- are prevalent in both the natural and consumer worlds. These systems are intrinsically physical in composition and are embedded into real space, properties that…

Quantitative Methods · Quantitative Biology 2016-12-26 Lia Papadopoulos , Pablo Blinder , Henrik Ronellenfitsch , Florian Klimm , Eleni Katifori , David Kleinfeld , Danielle S. Bassett