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Multimodal medical data fusion has emerged as a transformative approach in smart healthcare, enabling a comprehensive understanding of patient health and personalized treatment plans. In this paper, a journey from data to information to…

Information Retrieval · Computer Science 2024-10-28 Thanveer Shaik , Xiaohui Tao , Lin Li , Haoran Xie , Juan D. Velásquez

Brain transcriptomics provides insights into the molecular mechanisms by which the brain coordinates its functions and processes. However, existing multimodal methods for predicting Alzheimer's disease (AD) primarily rely on imaging and…

Artificial Intelligence · Computer Science 2025-04-03 Shan Cong , Zhoujie Fan , Hongwei Liu , Yinghan Zhang , Xin Wang , Haoran Luo , Xiaohui Yao

Alzheimer's disease (AD) is an incurable neurodegenerative condition leading to cognitive and functional deterioration. Given the lack of a cure, prompt and precise AD diagnosis is vital, a complex process dependent on multiple factors and…

Computer Vision and Pattern Recognition · Computer Science 2024-03-26 Guangqian Yang , Kangrui Du , Zhihan Yang , Ye Du , Yongping Zheng , Shujun Wang

Medical image classification plays a crucial role in computer-aided clinical diagnosis. While deep learning techniques have significantly enhanced efficiency and reduced costs, the privacy-sensitive nature of medical imaging data…

Computer Vision and Pattern Recognition · Computer Science 2024-07-04 Sufen Ren , Yule Hu , Shengchao Chen , Guanjun Wang

Mild Cognitive Impairment (MCI) serves as a prodromal stage of Alzheimer's Disease (AD), where early identification and intervention can effectively slow the progression to dementia. However, diagnosing AD remains a significant challenge in…

Artificial Intelligence · Computer Science 2025-11-07 Yutao Jin , Haowen Xiao , Junyong Zhai , Yuxiao Li , Jielei Chu , Fengmao Lv , Yuxiao Li

We introduce a novel framework for the classification of functional data supported on nonlinear, and possibly random, manifold domains. The motivating application is the identification of subjects with Alzheimer's disease from their…

Methodology · Statistics 2024-04-15 Eardi Lila , Wenbo Zhang , Swati Rane Levendovszky

This study introduces a novel multimodal food recognition framework that effectively combines visual and textual modalities to enhance classification accuracy and robustness. The proposed approach employs a dynamic multimodal fusion…

Computer Vision and Pattern Recognition · Computer Science 2025-08-06 Prateek Mittal , Puneet Goyal , Joohi Chauhan

The diagnosis of medical diseases faces challenges such as the misdiagnosis of small lesions. Deep learning, particularly multimodal approaches, has shown great potential in the field of medical disease diagnosis. However, the differences…

Computer Vision and Pattern Recognition · Computer Science 2025-08-07 Jianxun Yu , Ruiquan Ge , Zhipeng Wang , Cheng Yang , Chenyu Lin , Xianjun Fu , Jikui Liu , Ahmed Elazab , Changmiao Wang

The widespread adoption of Electronic Health Record (EHR) systems in healthcare institutes has generated vast amounts of medical data, offering significant opportunities for improving healthcare services through deep learning techniques.…

Machine Learning · Computer Science 2024-01-23 Suhan Cui , Jiaqi Wang , Yuan Zhong , Han Liu , Ting Wang , Fenglong Ma

We introduce Mediffusion -- a new method for semi-supervised learning with explainable classification based on a joint diffusion model. The medical imaging domain faces unique challenges due to scarce data labelling -- insufficient for…

Computer Vision and Pattern Recognition · Computer Science 2024-11-15 Joanna Kaleta , Paweł Skierś , Jan Dubiński , Przemysław Korzeniowski , Kamil Deja

In diagnosing challenging conditions such as Alzheimer's disease (AD), imaging is an important reference. Non-imaging patient data such as patient information, genetic data, medication information, cognitive and memory tests also play a…

Machine Learning · Computer Science 2023-06-01 Yingjie Feng , Jun Wang , Xianfeng Gu , Xiaoyin Xu , Min Zhang

Multimodal medical information processing is currently the epicenter of intense interdisciplinary research, as proper data fusion may lead to more accurate diagnoses. Moreover, multimodality may disambiguate cases of co-morbidity. This…

Information Retrieval · Computer Science 2017-02-23 Georgios Drakopoulos , Vasileios Megalooikonomou

In hospitals, data are siloed to specific information systems that make the same information available under different modalities such as the different medical imaging exams the patient undergoes (CT scans, MRI, PET, Ultrasound, etc.) and…

Computer Vision and Pattern Recognition · Computer Science 2021-02-03 Tristan Sylvain , Francis Dutil , Tess Berthier , Lisa Di Jorio , Margaux Luck , Devon Hjelm , Yoshua Bengio

Pathology foundation models (PFMs) have demonstrated strong representational capabilities through self-supervised pre-training on large-scale, unannotated histopathology image datasets. However, their diverse yet opaque pretraining…

Computer Vision and Pattern Recognition · Computer Science 2025-09-15 Yuxiang Xiao , Yang Hu , Bin Li , Tianyang Zhang , Zexi Li , Huazhu Fu , Jens Rittscher , Kaixiang Yang

Current artificial intelligence models for medical imaging are predominantly single modality and single disease. Attempts to create multimodal and multi-disease models have resulted in inconsistent clinical accuracy. Furthermore, training…

In the realm of neuroscience, identifying distinctive patterns associated with neurological disorders via brain networks is crucial. Resting-state functional magnetic resonance imaging (fMRI) serves as a primary tool for mapping these…

Image and Video Processing · Electrical Eng. & Systems 2025-10-27 Jiaxing Xu , Mengcheng Lan , Xia Dong , Kai He , Wei Zhang , Qingtian Bian , Yiping Ke

Generative AI framework-based modeling and prediction of longitudinal human brain images offer an efficient mechanism to track neurodegenerative progression, essential for the assessment of diseases like Alzheimer's. Among the existing…

Computer Vision and Pattern Recognition · Computer Science 2026-03-03 Ayantika Das , Keerthi Ram , Mohanasankar Sivaprakasam

Computer-aided diagnosis (CAD) systems play a crucial role in analyzing neuroimaging data for neurological and psychiatric disorders. However, small-sample studies suffer from low reproducibility, while large-scale datasets introduce…

Machine Learning · Computer Science 2025-08-12 Xinglin Zhao , Yanwen Wang , Xiaobo Liu , Yanrong Hao , Rui Cao , Xin Wen

Effective fusion of data from multiple modalities, such as video, speech, and text, is challenging due to the heterogeneous nature of multimodal data. In this paper, we propose adaptive fusion techniques that aim to model context from…

Computation and Language · Computer Science 2021-01-27 Gaurav Sahu , Olga Vechtomova

In the health domain, decisions are often based on different data modalities. Thus, when creating prediction models, multimodal fusion approaches that can extract and combine relevant features from different data modalities, can be highly…

Artificial Intelligence · Computer Science 2024-02-20 Mafalda Malafaia , Thalea Schlender , Peter A. N. Bosman , Tanja Alderliesten