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Deep learning relies heavily on data augmentation to mitigate limited data, especially in medical imaging. Recent multimodal learning integrates text and images for segmentation, known as referring or text-guided image segmentation.…

Computer Vision and Pattern Recognition · Computer Science 2025-10-15 Shurong Chai , Rahul Kumar JAIN , Rui Xu , Shaocong Mo , Ruibo Hou , Shiyu Teng , Jiaqing Liu , Lanfen Lin , Yen-Wei Chen

Early and accurate diagnosis of Alzheimer's disease (AD) remains a critical challenge in neuroimaging-based clinical decision support systems. In this work, we propose a novel hybrid deep learning framework that integrates Topological Data…

Computer Vision and Pattern Recognition · Computer Science 2026-02-03 Faisal Ahmed

Multimodal medical images play a crucial role in the precise and comprehensive clinical diagnosis. Diffusion model is a powerful strategy to synthesize the required medical images. However, existing approaches still suffer from the problem…

Computer Vision and Pattern Recognition · Computer Science 2025-05-28 Jiahua Xu , Dawei Zhou , Lei Hu , Zaiyi Liu , Nannan Wang , Xinbo Gao

Multimodal medical image fusion helps in combining contrasting features from two or more input imaging modalities to represent fused information in a single image. One of the pivotal clinical applications of medical image fusion is the…

Image and Video Processing · Electrical Eng. & Systems 2019-09-20 Nishant Kumar , Nico Hoffmann , Martin Oelschlägel , Edmund Koch , Matthias Kirsch , Stefan Gumhold

Retinal diseases spanning a broad spectrum can be effectively identified and diagnosed using complementary signals from multimodal data. However, multimodal diagnosis in ophthalmic practice is typically challenged in terms of data…

Computer Vision and Pattern Recognition · Computer Science 2026-02-04 Lu Zhang , Huizhen Yu , Zuowei Wang , Fu Gui , Yatu Guo , Wei Zhang , Mengyu Jia

Medical image segmentation - the prerequisite of numerous clinical needs - has been significantly prospered by recent advances in convolutional neural networks (CNNs). However, it exhibits general limitations on modeling explicit long-range…

Computer Vision and Pattern Recognition · Computer Science 2021-07-13 Yundong Zhang , Huiye Liu , Qiang Hu

Medical multimodal representation learning aims to integrate heterogeneous data into unified patient representations to support clinical outcome prediction. However, real-world medical datasets commonly contain systematic biases from…

Machine Learning · Computer Science 2026-05-19 Xiaoguang Zhu , Linxiao Gong , Lianlong Sun , Yang Liu , Haoyu Wang , Jing Liu

Successful identification of blood vessel blockage is a crucial step for Alzheimer's disease diagnosis. These blocks can be identified from the spatial and time-depth variable Two-Photon Excitation Microscopy (TPEF) images of the brain…

Image and Video Processing · Electrical Eng. & Systems 2022-11-08 Partho Ghosh , Md. Abrar Istiak , Mir Sayeed Mohammad , Swapnil Saha , Uday Kamal

Machine learning models for medical images can help physicians diagnose and manage diseases. However, due to the fact that medical image annotation requires a great deal of manpower and expertise, as well as the fact that clinical…

Image and Video Processing · Electrical Eng. & Systems 2023-11-21 Can Li , Sheng Shao , Junyi Qu , Shuchao Pang , Mehmet A. Orgun

Healthcare relies on multiple types of data, such as medical images, genetic information, and clinical records, to improve diagnosis and treatment. However, missing data is a common challenge due to privacy restrictions, cost, and technical…

Machine Learning · Computer Science 2025-03-13 Nazanin Moradinasab , Saurav Sengupta , Jiebei Liu , Sana Syed , Donald E. Brown

Real-world problems are often dependent on multiple data modalities, making multimodal fusion essential for leveraging diverse information sources. In high-stakes domains, such as in healthcare, understanding how each modality contributes…

Neural and Evolutionary Computing · Computer Science 2025-05-19 Mafalda Malafaia , Thalea Schlender , Tanja Alderliesten , Peter A. N. Bosman

Mental disorders are among the foremost contributors to the global healthcare challenge. Research indicates that timely diagnosis and intervention are vital in treating various mental disorders. However, the early somatization symptoms of…

Computer Vision and Pattern Recognition · Computer Science 2024-09-05 Yichun Li , Shuanglin Li , Syed Mohsen Naqvi

Multimodal neuroimaging provides complementary structural and functional insights into both human brain organization and disease-related dynamics. Recent studies demonstrate enhanced diagnostic sensitivity for Alzheimer's disease (AD)…

Multimedia · Computer Science 2025-04-24 Yuxiang Wei , Yanteng Zhang , Xi Xiao , Tianyang Wang , Xiao Wang , Vince D. Calhoun

We propose a unified optimization framework that combines neural networks with dictionary learning to model complex interactions between resting state functional MRI and behavioral data. The dictionary learning objective decomposes patient…

Machine Learning · Computer Science 2024-11-21 Niharika Shimona D'Souza , Mary Beth Nebel , Nicholas Wymbs , Stewart Mostofsky , Archana Venkataraman

This paper presents a novel approach towards creating a foundational model for aligning neural data and visual stimuli across multimodal representationsof brain activity by leveraging contrastive learning. We used electroencephalography…

Computer Vision and Pattern Recognition · Computer Science 2024-11-18 Matteo Ferrante , Tommaso Boccato , Grigorii Rashkov , Nicola Toschi

Magnetic Resonance Imaging (MRI) provides detailed structural information, while functional MRI (fMRI) captures temporal brain activity. In this work, we present a multimodal deep learning framework that integrates MRI and fMRI for…

Computer Vision and Pattern Recognition · Computer Science 2026-03-17 Anima Kujur , Zahra Monfared

Alzheimer's Disease (AD) is the most common neurodegenerative disorder with one of the most complex pathogeneses, making effective and clinically actionable decision support difficult. The objective of this study was to develop a novel…

Machine Learning · Computer Science 2022-09-27 Michal Golovanevsky , Carsten Eickhoff , Ritambhara Singh

Oral cancer is frequently diagnosed at later stages due to its similarity to other lesions. Existing research on computer aided diagnosis has made progress using deep learning; however, most approaches remain limited by small, imbalanced…

Computer Vision and Pattern Recognition · Computer Science 2026-01-06 Joy Naoum , Revana Salama , Ali Hamdi

In the medical multi-modal frameworks, the alignment of cross-modality features presents a significant challenge. However, existing works have learned features that are implicitly aligned from the data, without considering the explicit…

Computer Vision and Pattern Recognition · Computer Science 2024-06-17 Chong Ma , Hanqi Jiang , Wenting Chen , Yiwei Li , Zihao Wu , Xiaowei Yu , Zhengliang Liu , Lei Guo , Dajiang Zhu , Tuo Zhang , Dinggang Shen , Tianming Liu , Xiang Li

In visual object classification, humans often justify their choices by comparing objects to prototypical examples within that class. We may therefore increase the interpretability of deep learning models by imbuing them with a similar style…

Computer Vision and Pattern Recognition · Computer Science 2023-10-26 Ayodeji Ijishakin , Ahmed Abdulaal , Adamos Hadjivasiliou , Sophie Martin , James Cole
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