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The dynamics of single cell migration on flat surfaces is usually modeled by a Langevin-like problem consisting of ballistic motion for short periods and random walk. for long periods. Conversely, recent studies have revealed a previously…

We address the existence and of solutions for the Euler-plate free-boundary system modeling an interaction of a three-dimensional inviscid fluid and an evolving plate. We prove the local existence and uniqueness of solutions for initial…

Analysis of PDEs · Mathematics 2025-01-23 Mustafa Sencer Aydın , Igor Kukavica , Amjad Tuffaha

In this paper we derived a model which describes the swelling dynamics of a gel and study the system in one-dimensional geometry with a free boundary. The governing equations are hyperbolic with a weakly dissipative source. Using a…

Analysis of PDEs · Mathematics 2013-03-27 M. Carme Calderer , Robin Ming Chen

The actomyosin cortex, a thin layer of a cross-linked polymer network near the cell surface, generates active forces that are responsible for cell shape changes. Many developmental processes that involve such cell shape changes, most…

Soft Condensed Matter · Physics 2026-02-26 Da Gao , Alexander Mietke , Rui Ma

Contractile forces are essential for many developmental processes involving cell shape change and tissue deformation. Recent experiments on reconstituted actomyosin networks, the major component of the contractile machinery, have shown that…

Biological Physics · Physics 2012-05-31 Shenshen Wang , Peter G. Wolynes

A global existence result is established for a free boundary problem of planar magnetohydrodynamic fluid flows with radiation and large initial data. Particularly, it is novelty to embrace the constant transport coefficient. As a…

Analysis of PDEs · Mathematics 2011-10-28 Xulong Qin , Zheng-an Yao

We develop and analyze a model for a flat microbial droplet growing on the surface of a three-dimensional viscous fluid. The model describes growth-induced stresses at the fluid surface, density variations in the bulk due to nutrient…

Fluid Dynamics · Physics 2026-05-20 Vicente Gomez Herrera , Scott Weady

Cell spreading is investigated at various scales in order to understand motility of living cells which is essential for a range of physiological activities in higher organisms as well as in microbes. At a microscopic scale, it has been seen…

Cell Behavior · Quantitative Biology 2009-11-13 A. Bhattacharyay

The mixing problem is classically encountered in the study of differential equations applied to fluid dynamics. An understanding of fluid movement under constraints is particularly important in the field of medicine as many therapeutics and…

Medical Physics · Physics 2024-02-05 Neil Zhao

A discrete model and the regular solution approximation are applied to describe the effect of grain boundary motion on grain boundary phase transformations in a binary alloy. The model predicts all thermodynamic properties of the grain…

Materials Science · Physics 2019-05-13 Y. Mishin

We discovered a class of self-similar solutions in nonlinear models describing the formation of morphogen gradients, the concentration fields of molecules acting as spatial regulators of cell differention in developing tissues. These models…

Quantitative Methods · Quantitative Biology 2015-05-28 Cyrill B. Muratov , Peter V. Gordon , Stanislav Y. Shvartsman

Eukaryotic cell motility involves a complex network of interactions between biochemical components and mechanical processes. The cell employs this network to polarize and induce shape changes that give rise to membrane protrusions and…

Cell Behavior · Quantitative Biology 2022-01-03 E. Moreno , S. Flemming , F. Font , M. Holschneider , C. Beta , S. Alonso

We suggest a 3D phase field model to describe 3D cell spreading on a flat substrate. The model is a simplified version of a minimal model that was developed in [1]. Our model couples the order parameter $u$ with 3D polarization…

Biological Physics · Physics 2021-06-25 Mohammad Abu Hamed , Alexander A. Nepomnyashchy

We consider the dynamics of an electrostatically actuated thin elastic plate being clamped at its boundary above a rigid plate. The model includes the harmonic electrostatic potential in the three-dimensional time-varying region between the…

Analysis of PDEs · Mathematics 2015-06-02 Philippe Laurencot , Christoph Walker

Amoeboid cell motility is relevant in a wide variety of biomedical applications such as wound healing, cancer metastasis, and embryonic morphogenesis. It is characterized by pronounced changes of the cell shape associated with expansions…

Cell Behavior · Quantitative Biology 2022-10-25 Daniel Schindler , Ted Moldenhawer , Carsten Beta , Wilhelm Huisinga , Matthias Holschneider

We use the image solution technique to compute the leading order frequency-dependent self-mobility function of a small solid particle moving perpendicular to the surface of a spherical capsule whose membrane possesses shearing and bending…

Fluid Dynamics · Physics 2017-02-01 Abdallah Daddi-Moussa-Ider , Stephan Gekle

A living cell actively generates traction forces on its environment with its actin cytoskeleton. These forces deform the cell elastic substrate which, in turn, affects the traction forces exerted by the cell and can consequently modify the…

Biological Physics · Physics 2022-02-03 H. Chelly , A. Jahangiri , M. Mireux , J. Étienne , D. K. Dysthe , C. Verdier , P. Recho

In an effort to study the stability of contact lines in fluids, we consider the dynamics of an incompressible viscous Stokes fluid evolving in a two-dimensional open-top vessel under the influence of gravity. This is a free boundary…

Analysis of PDEs · Mathematics 2017-10-25 Yan Guo , Ian Tice

The immersed boundary method is a mathematical formulation and numerical method for solving fluid-structure interaction problems. For many biological problems, such as models that include the cell membrane, the immersed structure is a…

Numerical Analysis · Mathematics 2018-06-07 Ondrej Maxian , Andrew T. Kassen , Wanda Strychalski

We study the motion of an incompressible perfect liquid body in vacuum. This can be thought of as a model for the motion of the ocean or a star. The free surface moves with the velocity of the liquid and the pressure vanishes on the free…

Analysis of PDEs · Mathematics 2007-05-23 Hans Lindblad