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Qubit-efficient optimization studies how large combinatorial problems can be addressed with quantum circuits whose width is far smaller than the number of logical variables. In quadratic unconstrained binary optimization (QUBO), objective…

Quantum Physics · Physics 2026-01-13 Gordon Ma , Dimitris G. Angelakis

We present a new hybrid, local search algorithm for quantum approximate optimization of constrained combinatorial optimization problems. We focus on the Maximum Independent Set problem and demonstrate the ability of quantum local search to…

Quantum Physics · Physics 2022-08-24 Teague Tomesh , Zain H. Saleem , Martin Suchara

Due to the expected disparity in quantum vs. classical clock speeds, quantum advantage for branch and bound algorithms is more likely achievable in settings involving large search trees and low operator evaluation costs. Therefore, in this…

Optimization and Control · Mathematics 2024-07-30 Thomas Häner , Kyle E. C. Booth , Sima E. Borujeni , Elton Yechao Zhu

The peptide-protein docking problem is an important problem in structural biology that facilitates rational and efficient drug design. In this work, we explore modeling and solving this problem with the quantum-amenable quadratic…

We investigate the use of amplitude amplification on the gate-based model of quantum computing as a means for solving combinatorial optimization problems. This study focuses primarily on QUBO (quadratic unconstrained binary optimization)…

Quantum Physics · Physics 2023-02-02 Daniel Koch , Massimiliano Cutugno , Saahil Patel , Laura Wessing , Paul M. Alsing

Programmable quantum systems based on Rydberg atom arrays have recently been used for hardware-efficient tests of quantum optimization algorithms [Ebadi et al., Science, 376, 1209 (2022)] with hundreds of qubits. In particular, the maximum…

Quantum imaginary time evolution (QITE) is one of the promising candidates for finding eigenvalues and eigenstates of a Hamiltonian. However, the original QITE proposal [Nat. Phys. 16, 205-210 (2020)], which approximates the imaginary time…

Quantum Physics · Physics 2023-09-27 Yifei Huang , Yuguo Shao , Weiluo Ren , Jinzhao Sun , Dingshun Lv

The increasing complexity of industrial scheduling and transport routing problems motivates the study of alternative optimization formulations and computational paradigms. In this work, we study how higher-order unconstrained binary…

In this paper we analyze the performance of the Quantum Adiabatic Evolution algorithm on a variant of Satisfiability problem for an ensemble of random graphs parametrized by the ratio of clauses to variables, $\gamma=M/N$. We introduce a…

Quantum Physics · Physics 2009-11-10 V. N. Smelyanskiy , S. Knysh , R. D. Morris

The escalating complexity of modern machine learning necessitates solving challenging non-convex optimization problems, particularly in high-dimensional regimes and scenarios contaminated by gross outliers. Traditional approaches, relying…

Computational Engineering, Finance, and Science · Computer Science 2026-05-11 Kandula Eswara Sai Kumar , Parth Dhananjay Danve , Abhishek Chopra , Rut Lineswala

Most quantum algorithms designed to generate or probe properties of the ground state of a quantum many-body system require as input an initial state with a large overlap with the desired ground state. One approach for preparing such a…

Solving combinatorial optimization problems on current noisy quantum devices is currently being advocated for (and restricted to) binary polynomial optimization with equality constraints via quantum heuristic approaches. This is achieved…

Quantum Physics · Physics 2021-02-04 Claudio Gambella , Andrea Simonetto

We introduce a quantum algorithm that produces approximate solutions for combinatorial optimization problems. The algorithm depends on a positive integer p and the quality of the approximation improves as p is increased. The quantum circuit…

Quantum Physics · Physics 2014-11-17 Edward Farhi , Jeffrey Goldstone , Sam Gutmann

It is hoped that quantum computers will offer advantages over classical computers for combinatorial optimization. Here, we introduce a feedback-based strategy for quantum optimization, where the results of qubit measurements are used to…

Quantum Physics · Physics 2023-01-05 Alicia B. Magann , Kenneth M. Rudinger , Matthew D. Grace , Mohan Sarovar

Quadratic Unconstrained Binary Optimization (QUBO) is a generic technique to model various NP-hard combinatorial optimization problems in the form of binary variables. The Hamiltonian function is often used to formulate QUBO problems where…

Artificial Intelligence · Computer Science 2023-09-29 Redwan Ahmed Rizvee , Md. Mosaddek Khan

The Quadratic Unconstrained Binary Optimization (QUBO) model has gained prominence in recent years with the discovery that it unifies a rich variety of combinatorial optimization problems. By its association with the Ising problem in…

Data Structures and Algorithms · Computer Science 2019-11-06 Fred Glover , Gary Kochenberger , Yu Du

MaxCut is a key NP-Hard combinatorial optimization graph problem with extensive theoretical and industrial applications, including the Ising model and chip design. While quantum computing offers new solutions for such combinatorial…

Quantum Physics · Physics 2023-11-27 Yovav Tene-Cohen , Tomer Kelman , Ohad Lev , Adi Makmal

We demonstrate that the search space of the quadratic assignment problem (QAP), known as an NP-hard combinatorial optimization problem, can be reduced using Grover adaptive search (GAS) with permutation preparation operator (PPO). To that…

We use exact enumeration to characterize the solutions of quadratic unconstrained binary optimization problems of less than 21 variables in terms of their distributions of Hamming distances to close-by solutions. We also perform experiments…

Quantum Physics · Physics 2025-11-04 Vrinda Mehta , Fengping Jin , Kristel Michielsen , Hans De Raedt

Many engineering problems involve the optimization of computationally expensive models for which derivative information is not readily available. The Bayesian optimization (BO) framework is a particularly promising approach for solving…

Optimization and Control · Mathematics 2022-02-10 Joel A. Paulson , Congwen Lu
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