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Multi-omics data integration is crucial for understanding complex diseases, yet limited sample sizes, noise, and heterogeneity often reduce predictive power. To address these challenges, we introduce Omics-GAN, a Generative Adversarial…

Quantitative Methods · Quantitative Biology 2025-10-24 Md Selim Reza , Sabrin Afroz , Mostafizer Rahman , Md Ashad Alam

The use of high-fidelity computational simulations promises to enable high-throughput hypothesis testing and optimisation of cancer therapies. However, increasing realism comes at the cost of increasing computational requirements. This…

Neural and Evolutionary Computing · Computer Science 2022-12-05 Richard J. Preen , Larry Bull , Andrew Adamatzky

Microarray technology is known as one of the most important tools for collecting DNA expression data. This technology allows researchers to investigate and examine types of diseases and their origins. However, microarray data are often…

Quantitative Methods · Quantitative Biology 2021-01-05 Babak Nouri-Moghaddam , Mehdi Ghazanfari , Mohammad Fathian

Feature selection in noisy label scenarios remains an understudied topic. We propose a novel genetic algorithm-based approach, the Noise-Aware Multi-Objective Feature Selection Genetic Algorithm (NMFS-GA), for selecting optimal feature…

Machine Learning · Computer Science 2025-09-30 Vandad Imani , Elaheh Moradi , Carlos Sevilla-Salcedo , Vittorio Fortino , Jussi Tohka

This study tasckles the problem of many-objective sequence optimization for semi-automated robotic disassembly operations. To this end, we employ a many-objective genetic algorithm (MaOGA) algorithm inspired by the Non-dominated Sorting…

Robotics · Computer Science 2024-01-04 Takuya Kiyokawa , Kensuke Harada , Weiwei Wan , Tomoki Ishikura , Naoya Miyaji , Genichiro Matsuda

Generating a novel and optimized molecule with desired chemical properties is an essential part of the drug discovery process. Failure to meet one of the required properties can frequently lead to failure in a clinical test which is costly.…

Machine Learning · Computer Science 2020-10-28 Bonggun Shin , Sungsoo Park , JinYeong Bak , Joyce C. Ho

\textit{Objectives}: Data scarcity and domain shifts lead to biased training sets that do not accurately represent deployment conditions. A related practical problem is cross-modal image segmentation, where the objective is to segment…

Image and Video Processing · Electrical Eng. & Systems 2024-04-01 Guillaume Sallé , Pierre-Henri Conze , Julien Bert , Nicolas Boussion , Dimitris Visvikis , Vincent Jaouen

The $(1+(\lambda,\lambda))$ genetic algorithm is a recently proposed single-objective evolutionary algorithm with several interesting properties. We show that its main working principle, mutation with a high rate and crossover as repair…

Neural and Evolutionary Computing · Computer Science 2022-10-10 Benjamin Doerr , Omar El Hadri , Adrien Pinard

Constrained multi-objective optimization problems (CMOPs) are of great significance in the context of practical applications, ranging from scientific to engineering domains. Most existing constrained multi-objective evolutionary algorithms…

Neural and Evolutionary Computing · Computer Science 2026-03-18 Shuai Shao , Ye Tian , Shangshang Yang , Xingyi Zhang

'Hybrid meta-heuristics' is one of the most interesting recent trends in the field of optimization and feature selection (FS). In this paper, we have proposed a binary variant of Atom Search Optimization (ASO) and its hybrid with Simulated…

Computer Vision and Pattern Recognition · Computer Science 2020-05-19 Kushal Kanti Ghosh , Ritam Guha , Soulib Ghosh , Suman Kumar Bera , Ram Sarkar

To fast approximate maximum likelihood estimators with massive data, this paper studies the Optimal Subsampling Method under the A-optimality Criterion (OSMAC) for generalized linear models. The consistency and asymptotic normality of the…

Methodology · Statistics 2021-06-15 Mingyao Ai , Jun Yu , Huiming Zhang , HaiYing Wang

Decades of progress in simulation-based surrogate-assisted optimization and unprecedented growth in computational power have enabled researchers and practitioners to optimize previously intractable complex engineering problems. This paper…

Neural and Evolutionary Computing · Computer Science 2022-12-14 Qi Huang , Roy de Winter , Bas van Stein , Thomas Bäck , Anna V. Kononova

It has been found that stochastic algorithms often find good solutions much more rapidly than inherently-batch approaches. Indeed, a very useful rule of thumb is that often, when solving a machine learning problem, an iterative technique…

Machine Learning · Computer Science 2013-08-19 Andrew Cotter

Microarray techniques are widely used in Gene expression analysis. These techniques are based on discovering submatrices of genes that share similar expression patterns across a set of experimental conditions with coherence constraint.…

Quantitative Methods · Quantitative Biology 2020-01-27 Bilal Taher , Muhammad. H Fares , Saeed Jalili

Multi-objective evolutionary algorithms (MOEAs) are essential for solving complex optimization problems, such as the diet problem, where balancing conflicting objectives, like cost and nutritional content, is crucial. However, most MOEAs…

Neural and Evolutionary Computing · Computer Science 2026-01-05 Gustavo V. Nascimento , Ivan R. Meneghini , Valéria Santos , Eduardo Luz , Gladston Moreira

To solve real-world expensive constrained multi-objective optimization problems (ECMOPs), surrogate/approximation models are commonly incorporated in evolutionary algorithms to pre-select promising candidate solutions for evaluation.…

Neural and Evolutionary Computing · Computer Science 2024-05-24 Kamrul Hasan Rahi

An emerging optimisation problem from the real-world applications, named the multi-point dynamic aggregation (MPDA) problem, has become one of the active research topics of the multi-robot system. This paper focuses on a multi-objective…

Neural and Evolutionary Computing · Computer Science 2021-05-12 Guanqiang Gao , Bin Xin , Yi Mei , Shuxin Ding , Juan Li

Multi-objective optimization is a common problem in practical applications, and multi-objective evolutionary algorithm (MOEA) is considered as one of the effective methods to solve these problems. However, their randomness sometimes…

Neural and Evolutionary Computing · Computer Science 2024-10-04 Wanyi Liu , Long Chen , Zhenzhou Tang

Surrogate-assisted evolutionary algorithms have been widely developed to solve complex and computationally expensive multi-objective optimization problems in recent years. However, when dealing with high-dimensional optimization problems,…

Neural and Evolutionary Computing · Computer Science 2024-03-19 Guodong Chen , Jiu Jimmy Jiao , Xiaoming Xue , Zhongzheng Wang

The research community continues to seek increasingly more advanced synthetic data generators to reliably evaluate the strengths and limitations of machine learning methods. This work aims to increase the availability of datasets…

Machine Learning · Computer Science 2026-01-30 Joanna Komorniczak
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