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The field of biomedical imaging has undergone a rapid growth in recent years, mostly due to the implementation of ad-hoc designed experimental setups, theoretical support methods and numerical reconstructions. Especially for biological…

Biological Physics · Physics 2017-06-30 Daniele Ancora

Molecular fluorescence microscopy is a leading approach to super-resolution and nanoscale imaging in life and material sciences. However, super-resolution fluorescence microscopy is often bottlenecked by system-specific calibrations and…

The resolving ability of widefield fluorescence microscopy is fundamentally limited by out-of-focus background owing to its low axial resolution, particularly for densely labeled biological samples. Although total internal reflection…

Super-resolution imaging with advanced optical systems has been revolutionizing technical analysis in various fields from biological to physical sciences. However, many objects are hidden by strongly scattering media such as rough wall…

Optics · Physics 2021-09-06 Dong Wang , Sujit Kumar Sahoo , Cuong Dang

Three-photon (3P) microscopy is getting traction due to its superior performance in deep tissues. Yet, aberrations and light scattering still pose one of the main limitations in the attainable depth ranges for high-resolution imaging. Here,…

The ability to see around corners, i.e., recover details of a hidden scene from its reflections in the surrounding environment, is of considerable interest in a wide range of applications. However, the diffuse nature of light reflected from…

The correct insertion of virtual objects in images of real-world scenes requires a deep understanding of the scene's lighting, geometry and materials, as well as the image formation process. While recent large-scale diffusion models have…

Computer Vision and Pattern Recognition · Computer Science 2024-08-20 Ruofan Liang , Zan Gojcic , Merlin Nimier-David , David Acuna , Nandita Vijaykumar , Sanja Fidler , Zian Wang

Intrinsic image decomposition, which is an essential task in computer vision, aims to infer the reflectance and shading of the scene. It is challenging since it needs to separate one image into two components. To tackle this, conventional…

Computer Vision and Pattern Recognition · Computer Science 2020-05-28 Yunfei Liu , Yu Li , Shaodi You , Feng Lu

Optical imaging through complex scattering media is one of the major technical challenges with important applications in many research fields, ranging from biomedical imaging, astronomical telescopy, and spatially multiplex optical…

Imaging through optical multimode fibers (MMFs) has the potential to enable hair-thin endoscopes that reduce the invasiveness of imaging deep inside tissues and organs. Current approaches predominantly require active wavefront shaping and…

Optics · Physics 2021-12-13 Szu-Yu Lee , Vicente J. Parot , Brett E. Bouma , Martin Villiger

Full-field imaging through scattering media is fraught with many challenges. Despite many achievements in recent years, current imaging methods are too slow to deal with fast dynamics that occur for example in biomedical imaging. Here we…

Iterative projection algorithms are successfully being used as a substitute of lenses to recombine, numerically rather than optically, light scattered by illuminated objects. Images obtained computationally allow aberration-free…

Optics · Physics 2007-05-23 S. Marchesini

Polarimetric imaging can provide valuable information about biological samples in a wide range of applications. Detrimental scattering however currently limits the imaging depth of in-vivo imaging to approximately 1 transport mean free…

Optics · Physics 2020-10-28 Kai Ling C. Seow , Peter Török , Matthew R. Foreman

When waves propagate through a complex medium, they undergo several scattering events. This phenomenon is detrimental to imaging, as it causes full blurring of the image. Here we describe a method for detecting, localizing and…

Multispectral imaging has been used for numerous applications in e.g., environmental monitoring, aerospace, defense, and biomedicine. Here, we present a diffractive optical network-based multispectral imaging system trained using deep…

Optics · Physics 2023-04-07 Deniz Mengu , Anika Tabassum , Mona Jarrahi , Aydogan Ozcan

Mid-infrared photothermal microscopy is a new chemical imaging technology in which a visible beam senses the photothermal effect induced by a pulsed infrared laser. This technology provides infrared spectroscopic information at sub-micron…

Optics · Physics 2021-04-08 Yi Zhang , Haonan Zong , Cheng Zong , Yuying Tan , Meng Zhang , Yuewei Zhan , Ji-Xin Cheng

This paper addresses the problem of mirror surface reconstruction, and proposes a solution based on observing the reflections of a moving reference plane on the mirror surface. Unlike previous approaches which require tedious calibration,…

Computer Vision and Pattern Recognition · Computer Science 2021-01-26 Kai Han , Miaomiao Liu , Dirk Schnieders , Kwan-Yee K. Wong

While Fourier ptychography (FP) offers super-resolution for macroscopic imaging, its real-world application is severely hampered by atmospheric turbulence, a challenge largely unaddressed in existing macroscopic FP research operating under…

Fluorescence Molecular Tomography (FMT) is a promising technique for non-invasive 3D visualization of fluorescent probes, but its reconstruction remains challenging due to the inherent ill-posedness and reliance on inaccurate or…

Image and Video Processing · Electrical Eng. & Systems 2025-11-07 Shihan Zhao , Jianru Zhang , Yanan Wu , Linlin Li , Siyuan Shen , Xingjun Zhu , Guoyan Zheng , Jiahua Jiang , Wuwei Ren

Accurate determination of the complex effective permittivity is fundamental to optical material engineering, but it remains a critical metrology challenge for heterogeneous systems. In polymer blends and optical composites, scattering and…

Optics · Physics 2026-03-03 Proity Nayeeb Akbar