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This study investigates whether large language models, specifically GPT4, can match human capabilities in analogical reasoning within strategic decision making contexts. Using a novel experimental design involving source to target matching,…

Artificial Intelligence · Computer Science 2025-05-02 Phanish Puranam , Prothit Sen , Maciej Workiewicz

Medical image classifiers detect gastrointestinal diseases well, but they do not explain their decisions. Large language models can generate clinical text, yet they struggle with visual reasoning and often produce unstable or incorrect…

Computer Vision and Pattern Recognition · Computer Science 2026-02-24 Md. Najib Hasan , Imran Ahmad , Sourav Basak Shuvo , Md. Mahadi Hasan Ankon , Sunanda Das , Nazmul Siddique , Hui Wang

Large language models (LLMs) are increasingly embedded in AI-based tutoring systems. Can they faithfully model novice reasoning and metacognitive judgments? Existing evaluations emphasize problem-solving accuracy, overlooking the fragmented…

Computation and Language · Computer Science 2026-05-12 Conrad Borchers , Jill-Jênn Vie , Roger Azevedo

Large multimodal language models (MLLMs) such as GPT-4V and GPT-4o have achieved remarkable advancements in understanding and generating multimodal content, showcasing superior quality and capabilities across diverse tasks. However, their…

Computer Vision and Pattern Recognition · Computer Science 2025-01-09 Xuelu Feng , Yunsheng Li , Dongdong Chen , Mei Gao , Mengchen Liu , Junsong Yuan , Chunming Qiao

In this paper, we explore the challenges inherent to Large Language Models (LLMs) like GPT-4, particularly their propensity for hallucinations, logic mistakes, and incorrect conclusions when tasked with answering complex questions. The…

Computation and Language · Computer Science 2023-12-22 Xiang Li , Haoran Tang , Siyu Chen , Ziwei Wang , Anurag Maravi , Marcin Abram

Phenotype-driven gene prioritization is a critical process in the diagnosis of rare genetic disorders for identifying and ranking potential disease-causing genes based on observed physical traits or phenotypes. While traditional approaches…

Quantitative Methods · Quantitative Biology 2024-04-04 Junyoung Kim , Jingye Yang , Kai Wang , Chunhua Weng , Cong Liu

Large language models (LLMs) excel on many NLP benchmarks, but their behavior on real-world, semi-structured prediction remains underexplored. We present LlaMADRS, a benchmark for structured clinical assessment from dialogue built on the…

Human-Computer Interaction · Computer Science 2026-04-23 Gaoussou Youssouf Kebe , Jeffrey M. Girard , Einat Liebenthal , Justin Baker , Fernando De la Torre , Louis-Philippe Morency

Large Language Models (LLMs) are demonstrating remarkable human like capabilities across diverse domains, including psychological assessment. This study evaluates whether LLMs, specifically GPT-4o and GPT-4o mini, can infer Big Five…

Computation and Language · Computer Science 2025-01-14 Jianfeng Zhu , Ruoming Jin , Karin G. Coifman

Integrating large language models (LLMs) like DeepSeek R1 into healthcare requires rigorous evaluation of their reasoning alignment with clinical expertise. This study assesses DeepSeek R1's medical reasoning against expert patterns using…

Computation and Language · Computer Science 2025-04-02 Birger Moell , Fredrik Sand Aronsson , Sanian Akbar

Large language models (LLMs) offer a promising pre-screening tool, improving early disease detection and providing enhanced healthcare access for underprivileged communities. The early diagnosis of various diseases continues to be a…

Artificial Intelligence · Computer Science 2025-04-10 Umakanta Maharana , Sarthak Verma , Avarna Agarwal , Prakashini Mruthyunjaya , Dwarikanath Mahapatra , Sakir Ahmed , Murari Mandal

As Large Language Models (LLMs) are increasingly integrated into healthcare to address complex inquiries, ensuring their reliability remains a critical challenge. Recent studies have highlighted that generic LLMs often struggle in clinical…

Computation and Language · Computer Science 2026-04-01 Bian Sun , Zhenjian Wang , Orvill de la Torre , Zirui Wang

Large Language Models (LLMs) such as ChatGPT have shown remarkable abilities in producing human-like text. However, it is unclear how accurately these models internalize concepts that shape human thought and behavior. Here, we developed a…

Machine Learning · Computer Science 2025-07-01 Hiro Taiyo Hamada , Ippei Fujisawa , Genji Kawakita , Yuki Yamada

In recent years, the application of Large Language Models (LLMs) in healthcare has shown significant promise in improving the accessibility and dissemination of medical knowledge. This paper presents a detailed study of various LLMs trained…

Computation and Language · Computer Science 2024-08-09 Haoran Yu , Chang Yu , Zihan Wang , Dongxian Zou , Hao Qin

We present a benchmark for assessing the capability of Large Language Models (LLMs) to discern intercardinal directions between geographic locations and apply it to three prominent LLMs: GPT-3.5, GPT-4, and Llama-2. This benchmark…

Computation and Language · Computer Science 2024-06-05 Nir Fulman , Abdulkadir Memduhoğlu , Alexander Zipf

Recent advances in multimodal large language models enable new possibilities for image-based decision support. However, their reliability and operational trade-offs in neuroimaging remain insufficiently understood. We present a…

Computer Vision and Pattern Recognition · Computer Science 2026-03-27 Katarina Trojachanec Dineva , Stefan Andonov , Ilinka Ivanoska , Ivan Kitanovski , Sasho Gramatikov , Tamara Kostova , Monika Simjanoska Misheva , Kostadin Mishev

Doctors and patients alike increasingly use Large Language Models (LLMs) to diagnose clinical cases. However, unlike domains such as math or coding, where correctness can be objectively defined by the final answer, medical diagnosis…

Computation and Language · Computer Science 2025-05-21 Kevin Wu , Eric Wu , Rahul Thapa , Kevin Wei , Angela Zhang , Arvind Suresh , Jacqueline J. Tao , Min Woo Sun , Alejandro Lozano , James Zou

Multimodal Large Language Models (LLMs) introduce an emerging paradigm for medical imaging by interpreting scans through the lens of extensive clinical knowledge, offering a transformative approach to disease classification. This study…

Computer Vision and Pattern Recognition · Computer Science 2026-04-20 Md. Sazzadul Islam Prottasha , Nabil Walid Rafi

For years, semantic interoperability standards have sought to streamline the exchange of clinical data, yet their deployment remains time-consuming, resource-intensive, and technically challenging. To address this, we introduce a…

Computation and Language · Computer Science 2025-07-08 Alvaro Riquelme , Pedro Costa , Catalina Martinez

Since the release of ChatGPT and GPT-4, large language models (LLMs) and multimodal large language models (MLLMs) have attracted widespread attention for their exceptional capabilities in understanding, reasoning, and generation,…

Computation and Language · Computer Science 2024-12-31 Hanguang Xiao , Feizhong Zhou , Xingyue Liu , Tianqi Liu , Zhipeng Li , Xin Liu , Xiaoxuan Huang

Despite growing interest in using large language models (LLMs) in healthcare, current explorations do not assess the real-world utility and safety of LLMs in clinical settings. Our objective was to determine whether two LLMs can serve…

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