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Large Language Models (LLMs) are increasingly used in intelligent systems that perform reasoning, summarization, and code generation. Their ability to follow natural-language instructions, while powerful, also makes them vulnerable to a new…

Cryptography and Security · Computer Science 2025-11-13 Daniyal Ganiuly , Assel Smaiyl

This paper presents an in-depth analysis of the performance of seven different Large Language Models (LLMs) in solving a diverse set of math advanced calculus problems. The study aims to evaluate these models' accuracy, reliability, and…

Computation and Language · Computer Science 2025-03-07 In Hak Moon

This study evaluates the GPT-4 Large Language Model's abductive reasoning in complex fields like medical diagnostics, criminology, and cosmology. Using an interactive interview format, the AI assistant demonstrated reliability in generating…

Artificial Intelligence · Computer Science 2023-07-21 Remo Pareschi

Background: The potential of large language models (LLMs) to automate and support pharmacoepidemiologic study design is an emerging area of interest, yet their reliability remains insufficiently characterized. General-purpose LLMs often…

Computation and Language · Computer Science 2026-04-21 Xinyao Zhang , Nicole Sonne Heckmann , Manuela Del Castillo Suero , Francesco Paolo Speca , Maurizio Sessa

Background: Large Language Models (LLMs) are transforming artificial intelligence applications in healthcare due to their ability to understand, generate, and summarize complex medical text. They offer valuable support to clinicians,…

Computation and Language · Computer Science 2026-04-14 Subin Santhosh , Farwa Abbas , Hussain Ahmad , Claudia Szabo

Large Language Models (LLMs), typified by OpenAI's GPT, have marked a significant advancement in artificial intelligence. Trained on vast amounts of text data, LLMs are capable of understanding and generating human-like text across a…

Artificial Intelligence · Computer Science 2024-10-29 Haochen Zhang , Yuyang Dong , Chuan Xiao , Masafumi Oyamada

Lab results are often confusing and hard to understand. Large language models (LLMs) such as ChatGPT have opened a promising avenue for patients to get their questions answered. We aim to assess the feasibility of using LLMs to generate…

Computation and Language · Computer Science 2024-04-23 Zhe He , Balu Bhasuran , Qiao Jin , Shubo Tian , Karim Hanna , Cindy Shavor , Lisbeth Garcia Arguello , Patrick Murray , Zhiyong Lu

Purpose To evaluate the reasoning capabilities of large language models (LLMs) in performing root cause analysis (RCA) of radiation oncology incidents using narrative reports from the Radiation Oncology Incident Learning System (RO-ILS),…

Recent advances in large language models (LLMs) show potential for clinical applications, such as clinical decision support and trial recommendations. However, the GPT-4 LLM predicts an excessive number of ICD codes for medical coding…

Computation and Language · Computer Science 2023-11-27 Zhichao Yang , Sanjit Singh Batra , Joel Stremmel , Eran Halperin

Large language models (LLMs), such as LLaMA, Alpaca, Vicuna, GPT-3.5 and GPT-4, have advanced the performance of AI systems on various natural language processing tasks to human-like levels. However, their generalisation and robustness when…

Computation and Language · Computer Science 2025-01-20 Qiming Bao , Gael Gendron , Alex Yuxuan Peng , Wanjun Zhong , Neset Tan , Yang Chen , Michael Witbrock , Jiamou Liu

As educational systems evolve, ensuring that assessment items remain aligned with content standards is essential for maintaining fairness and instructional relevance. Traditional human alignment reviews are accurate but slow and…

Artificial Intelligence · Computer Science 2025-11-26 Farzan Karimi-Malekabadi , Pooya Razavi , Sonya Powers

Recently, Large Language Models (LLMs) have showcased remarkable capabilities in natural language understanding. While demonstrating proficiency in everyday conversations and question-answering situations, these models frequently struggle…

Computation and Language · Computer Science 2023-08-28 Chaoyi Wu , Weixiong Lin , Xiaoman Zhang , Ya Zhang , Yanfeng Wang , Weidi Xie

Large language models (LLMs) have recently showcased remarkable capabilities, spanning a wide range of tasks and applications, including those in the medical domain. Models like GPT-4 excel in medical question answering but may face…

Computation and Language · Computer Science 2025-07-02 Bowen Wang , Jiuyang Chang , Yiming Qian , Guoxin Chen , Junhao Chen , Zhouqiang Jiang , Jiahao Zhang , Yuta Nakashima , Hajime Nagahara

Large language models, such as GPT-4 and Med-PaLM, have shown impressive performance on clinical tasks; however, they require access to compute, are closed-source, and cannot be deployed on device. Mid-size models such as BioGPT-large,…

The evaluation and improvement of medical large language models (LLMs) are critical for their real-world deployment, particularly in ensuring accuracy, safety, and ethical alignment. Existing frameworks inadequately dissect domain-specific…

Computation and Language · Computer Science 2025-03-11 Luyi Jiang , Jiayuan Chen , Lu Lu , Xinwei Peng , Lihao Liu , Junjun He , Jie Xu

While large language models (LLMs), such as GPT-3, appear to be robust and general, their reasoning ability is not at a level to compete with the best models trained for specific natural language reasoning problems. In this study, we…

Computation and Language · Computer Science 2023-07-18 Zhun Yang , Adam Ishay , Joohyung Lee

Domain specific large language models are increasingly used to support patient education, triage, and clinical decision making in ophthalmology, making rigorous evaluation essential to ensure safety and accuracy. This study evaluated four…

This paper describes a rapid feasibility study of using GPT-4, a large language model (LLM), to (semi)automate data extraction in systematic reviews. Despite the recent surge of interest in LLMs there is still a lack of understanding of how…

Computation and Language · Computer Science 2025-02-14 Lena Schmidt , Kaitlyn Hair , Sergio Graziosi , Fiona Campbell , Claudia Kapp , Alireza Khanteymoori , Dawn Craig , Mark Engelbert , James Thomas

In recent years, groundbreaking advancements in natural language processing have culminated in the emergence of powerful large language models (LLMs), which have showcased remarkable capabilities across a vast array of domains, including…

Computation and Language · Computer Science 2023-12-11 Microsoft Research AI4Science , Microsoft Azure Quantum

Evaluating reasoning ability in Large Language Models (LLMs) is important for advancing artificial intelligence, as it transcends mere linguistic task performance. It involves understanding whether these models truly understand information,…

Artificial Intelligence · Computer Science 2025-10-29 Benjamin Grando Moreira