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Growing evidence from recent studies implies that microRNA or miRNA could serve as biomarkers in various complex human diseases. Since wet-lab experiments are expensive and time-consuming, computational techniques for miRNA-disease…

Quantitative Methods · Quantitative Biology 2021-11-30 Thi Ngan Dong , Megha Khosla

Safe predictions are a crucial requirement for integrating predictive models into clinical decision support systems. One approach for ensuring trustworthiness is to enable models' ability to express their uncertainty about individual…

Machine Learning · Computer Science 2026-03-10 L. Julián Lechuga López , Tim G. J. Rudner , Farah E. Shamout

Clinical notes contain rich patient information, such as diagnoses or medications, making them valuable for patient representation learning. Recent advances in large language models have further improved the ability to extract meaningful…

Machine Learning · Computer Science 2025-09-23 Zihan Liang , Ziwen Pan , Ruoxuan Xiong

Biomedical documents such as Electronic Health Records (EHRs) contain a large amount of information in an unstructured format. The data in EHRs is a hugely valuable resource documenting clinical narratives and decisions, but whilst the text…

Computation and Language · Computer Science 2019-12-24 Zeljko Kraljevic , Daniel Bean , Aurelie Mascio , Lukasz Roguski , Amos Folarin , Angus Roberts , Rebecca Bendayan , Richard Dobson

It is not clear how to target patients who are most likely to benefit from digital care management programs ex-ante, a shortcoming of current risk score based approaches. This study focuses on defining impactability by identifying those…

Quantitative Methods · Quantitative Biology 2019-05-16 Heather Mattie , Patrick Reidy , Patrik Bachtiger , Emily Lindemer , Mohammad Jouni , Trishan Panch

Drug safety research is crucial for maintaining public health, often requiring comprehensive data support. However, the resources currently available to the public are limited and fail to provide a comprehensive understanding of the…

Human-Computer Interaction · Computer Science 2024-07-03 Artem Bobrov , Domantas Saltenis , Zhaoyue Sun , Gabriele Pergola , Yulan He

In this paper, we provide guidance on how standard safety analyses and reporting of clinical trial safety data may need to be modified, given the potential impact of the COVID-19 pandemic. The impact could include missed visits, alternative…

Other Quantitative Biology · Quantitative Biology 2020-06-11 Mary Nilsson , Brenda Crowe , Greg Anglin , Greg Ball , Melvin Munsaka , Seta Shahin , Wei Wang

Background and Objective: Code assignment is of paramount importance in many levels in modern hospitals, from ensuring accurate billing process to creating a valid record of patient care history. However, the coding process is tedious and…

Computation and Language · Computer Science 2019-10-03 Jinmiao Huang , Cesar Osorio , Luke Wicent Sy

Existing approaches to protect the privacy of Electronic Health Records are either insufficient for existing medical laws or they are too restrictive in their usage. For example, smart card-based encryption systems require the patient to be…

Cryptography and Security · Computer Science 2015-06-12 Adebayo Omotosho , Omotanwa Adegbola , Barakat Adelakin , Adeyemi Adelakun , Justice Emuoyibofarhe

Metadata-the machine-readable descriptions of the data-are increasingly seen as crucial for describing the vast array of biomedical datasets that are currently being deposited in public repositories. While most public repositories have firm…

The process of electronic approach to writing and sending medical prescription promises to improve patient safety, health outcomes, maintaining patients privacy, promoting clinician acceptance and prescription security when compared with…

Computers and Society · Computer Science 2015-06-12 Adebayo Omotosho , Emuoyibofarhe Justice

Millions of individuals' well-being are challenged by the harms of substance use. Harm reduction as a public health strategy is designed to improve their health outcomes and reduce safety risks. Some large language models (LLMs) have…

Computation and Language · Computer Science 2025-07-30 Kaixuan Wang , Chenxin Diao , Jason T. Jacques , Zhongliang Guo , Shuai Zhao

Large-scale clinical databases offer opportunities for medical research, but their complexity creates barriers to effective use. The Medical Information Mart for Intensive Care (MIMIC-IV), one of the world's largest open-source electronic…

Information Retrieval · Computer Science 2026-05-21 Rafi Al Attrach , Pedro Moreira , Rajna Fani , Renato Umeton , Amelia Fiske , Leo Anthony Celi

This study examines integrating EHRs and NLP with large language models (LLMs) to improve healthcare data management and patient care. It focuses on using advanced models to create secure, HIPAA-compliant synthetic patient notes for…

Computation and Language · Computer Science 2025-06-03 Yao-Shun Chuang , Atiquer Rahman Sarkar , Yu-Chun Hsu , Noman Mohammed , Xiaoqian Jiang

The lack of standardized evaluation benchmarks in the medical domain for text inputs can be a barrier to widely adopting and leveraging the potential of natural language models for health-related downstream tasks. This paper revisited an…

Computation and Language · Computer Science 2025-04-30 Jesus Lovon , Thouria Ben-Haddi , Jules Di Scala , Jose G. Moreno , Lynda Tamine

Clinical decision-making relies on the integration of information across various data modalities, such as clinical time-series, medical images and textual reports. Compared to other domains, real-world medical data is heterogeneous in…

Image and Video Processing · Electrical Eng. & Systems 2025-08-14 Baraa Al Jorf , Farah Shamout

Large language models (LLMs) show promise for extracting information from Electronic Health Records (EHR) and supporting clinical decisions. However, deployment in clinical settings faces challenges due to hallucination risks. We propose…

Artificial Intelligence · Computer Science 2025-08-27 Yongwoo Song , Minbyul Jeong , Mujeen Sung

International Classification of Disease (ICD) coding procedure which refers to tagging medical notes with diagnosis codes has been shown to be effective and crucial to the billing system in medical sector. Currently, ICD codes are assigned…

Computation and Language · Computer Science 2021-04-22 Biplob Biswas , Thai-Hoang Pham , Ping Zhang

The integration of blockchain technology into healthcare presents a paradigm shift for secure data management, enabling decentralized and tamper-proof storage and sharing of sensitive Electronic Health Records (EHRs). However, existing…

Cryptography and Security · Computer Science 2025-10-16 Jucai Yang , Liang Li , Yiwei Gu , Haiqin Wu

The adoption of digital systems in healthcare has resulted in the accumulation of vast electronic health records (EHRs), offering valuable data for machine learning methods to predict patient health outcomes. However, single-visit records…

Machine Learning · Computer Science 2024-11-19 Eric Yang , Pengfei Hu , Xiaoxue Han , Yue Ning
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