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Cells are the fundamental unit of biological organization, and identifying them in imaging data - cell segmentation - is a critical task for various cellular imaging experiments. While deep learning methods have led to substantial progress…

Identification and counting of cells and mitotic figures is a standard task in diagnostic histopathology. Due to the large overall cell count on histological slides and the potential sparse prevalence of some relevant cell types or mitotic…

Computer Vision and Pattern Recognition · Computer Science 2017-09-08 Marc Aubreville , Maximilian Krappmann , Christof Bertram , Robert Klopfleisch , Andreas Maier

Microscopic examination of tissues or histopathology is one of the diagnostic procedures for detecting colorectal cancer. The pathologist involved in such an examination usually identifies tissue type based on texture analysis, especially…

Image and Video Processing · Electrical Eng. & Systems 2020-04-06 Srinath Jayachandran , Ashlin Ghosh

Accurate extraction of the Region of Interest is critical for successful ocular region-based biometrics. In this direction, we propose a new context-based segmentation approach, entitled Ocular Region Context Network (ORCNet), introducing a…

Computer Vision and Pattern Recognition · Computer Science 2022-04-18 Diego Rafael Lucio , Luiz A. Zanlorensi , Yandre Maldonado e Gomes da Costa , David Menotti

Breast cancer is one of the most common cancers among women worldwide, with early detection significantly increasing survival rates. Ultrasound imaging is a critical diagnostic tool that aids in early detection by providing real-time…

Image and Video Processing · Electrical Eng. & Systems 2023-05-23 Mingzhe Hu , Yuheng Li , Xiaofeng Yang

Different cell types aggregate and sort into hierarchical architectures during the formation of animal tissues. The resulting spatial organization depends (in part) on the strength of adhesion of one cell type to itself relative to other…

Quantitative Methods · Quantitative Biology 2023-08-02 Dhananjay Bhaskar , William Y. Zhang , Alexandria Volkening , Björn Sandstede , Ian Y. Wong

Salient Object Detection (SOD) with deep learning often requires substantial computational resources and large annotated datasets, making it impractical for resource-constrained applications. Lightweight models address computational demands…

Computer Vision and Pattern Recognition · Computer Science 2025-04-16 Leonardo M. Joao , Jancarlo F. Gomes , Silvio J. F. Guimaraes , Ewa Kijak , Alexandre X. Falcao

For Minimally Invasive Surgical (MIS) robots, accurate haptic interaction force feedback is essential for ensuring the safety of interacting with soft tissue. However, most existing MIS robotic systems cannot facilitate direct measurement…

Robotics · Computer Science 2025-01-16 Jiayin Wang , Mingfeng Yao , Yanran Wei , Xiaoyu Guo , Ayong Zheng , Weidong Zhao

Nuclei instance segmentation in hematoxylin and eosin (H&E)-stained images plays an important role in automated histological image analysis, with various applications in downstream tasks. While several machine learning and deep learning…

Computer Vision and Pattern Recognition · Computer Science 2026-01-29 Nima Torbati , Anastasia Meshcheryakova , Ramona Woitek , Sepideh Hatamikia , Diana Mechtcheriakova , Amirreza Mahbod

Over the last two decades, scientific literature has been blooming with various means of simulating epithelial cell colonies. Each of these simulations can be separated by their respective efficiency (expressed in terms of consumed…

Computational Physics · Physics 2022-12-20 Kevin Höllring , Ana-Sunčana Smith

Early detection of melanoma is difficult for the human eye but a crucial step towards reducing its death rate. Computerized detection of these melanoma and other skin lesions is necessary. The central research question in this paper is "How…

Image and Video Processing · Electrical Eng. & Systems 2019-10-24 Beril Sirmacek , Max Kivits

When applying automatic analysis of fluorescence or histopathological images of cells, it is necessary to partition, or de-clump, partially overlapping cell nuclei. In this work, I describe a method of partitioning partially overlapping…

Computer Vision and Pattern Recognition · Computer Science 2018-04-13 James Kapaldo

We propose a 3D convolutional neural network to simultaneously segment and detect cell nuclei in confocal microscopy images. Mirroring the co-dependency of these tasks, our proposed model consists of two serial components: the first part…

Image and Video Processing · Electrical Eng. & Systems 2018-09-07 Sundaresh Ram , Vicky T. Nguyen , Kirsten H. Limesand , Mert R. Sabuncu

Identify the cells' nuclei is the important point for most medical analyses. To assist doctors finding the accurate cell' nuclei location automatically is highly demanded in the clinical practice. Recently, fully convolutional neural…

Computer Vision and Pattern Recognition · Computer Science 2019-11-25 Tianyang Zhang , Rui Ma

The development of larger models for medical image analysis has led to increased performance. However, it also affected our ability to explain and validate model decisions. Models can use non-relevant parts of images, also called spurious…

Computer Vision and Pattern Recognition · Computer Science 2025-05-23 Théo Sourget , Michelle Hestbek-Møller , Amelia Jiménez-Sánchez , Jack Junchi Xu , Veronika Cheplygina

Live cell microscopy sequences exhibit complex spatial structures and complicated temporal behaviour, making their analysis a challenging task. Considering cell segmentation problem, which plays a significant role in the analysis, the…

Computer Vision and Pattern Recognition · Computer Science 2019-01-08 Assaf Arbelle , Tammy Riklin Raviv

Early detection of skin cancer, particularly melanoma, is crucial to enable advanced treatment. Due to the rapid growth in the numbers of skin cancers, there is a growing need of computerized analysis for skin lesions. The state-of-the-art…

Image and Video Processing · Electrical Eng. & Systems 2019-07-31 Manu Goyal , Amanda Oakley , Priyanka Bansal , Darren Dancey , Moi Hoon Yap

We propose the Recurrent Soft Attention Model, which integrates the visual attention from the original image to a LSTM memory cell through a down-sample network. The model recurrently transmits visual attention to the memory cells for…

Computer Vision and Pattern Recognition · Computer Science 2017-05-30 Liliang Ren

Background: The segment-anything model (SAM), introduced in April 2023, shows promise as a benchmark model and a universal solution to segment various natural images. It comes without previously-required re-training or fine-tuning specific…

Image and Video Processing · Electrical Eng. & Systems 2023-05-09 Sheng He , Rina Bao , Jingpeng Li , Jeffrey Stout , Atle Bjornerud , P. Ellen Grant , Yangming Ou

Foundation models have made incredible strides in achieving zero-shot or few-shot generalization, leveraging prompt engineering to mimic the problem-solving approach of human intelligence. However, when it comes to some foundation models…

Computer Vision and Pattern Recognition · Computer Science 2024-08-30 Luyao Tang , Yuxuan Yuan , Chaoqi Chen , Kunze Huang , Xinghao Ding , Yue Huang