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Cardiac fluid dynamics fundamentally involves interactions between complex blood flows and the structural deformations of the muscular heart walls and the thin, flexible valve leaflets. There has been longstanding scientific, engineering,…
The circulatory system, comprising the heart and blood vessels, is vital for nutrient transport, waste removal, and homeostasis. Traditional computational models often treat cardiac electromechanics and blood flow dynamics separately,…
The stomach plays a central role in digestion through coordinated muscle contractions, known as gastric peristalsis, driven by slow-wave electrophysiology. Understanding this process is critical for treating motility disorders such as…
Exploring fluid-structure interactions is essential for understanding the physical principle underlying flow control in biological and man-made systems. Traditionally, we assume that the geometry is known, and from it, the solution to the…
Cardiovascular waveforms contain information for clinical diagnosis. By "learning" and organizing the subtle change of waveform morphology from large amounts of raw waveform data, unsupervised manifold learning helps delineate a…
The reconstruction of electrical excitation patterns through the unobserved depth of the tissue is essential to realizing the potential of computational models in cardiac medicine. We have utilized experimental optical-mapping recordings of…
The prediction of heart surface potentials using measurements from the body's surface is known as the inverse problem of electrocardiography. It is an ill-posed problem due to the multiple factors that affect the heart signal as it…
In Electrical Impedance Tomography (EIT) one wants to image the conductivity distribution of a body from current and voltage measurements carried out on its boundary. In this paper we consider the underlying mathematical model, the inverse…
This article aims to present a general analysis of a class of inverse problems that consists in recovering the elliptic parameter maps in systems of PDEs, such as the linear elastic system, from the knowledge of some of their solutions.…
Estimating the shape and motion state of the myocardium is essential in diagnosing cardiovascular diseases.However, cine magnetic resonance (CMR) imaging is dominated by 2D slices, whose large slice spacing challenges inter-slice shape…
Electrical impedance tomography (EIT) is a non-invasive imaging technique, capable of reconstructing images of the electrical conductivity of tissues and materials. It is popular in diverse application areas, from medical imaging to…
In this paper we provide a representation formula for boundary voltage perturbations caused by internal conductivity inhomogeneities of low volume fraction in a simplified {\em monodomain model} describing the electric activity of the…
Slender structures, such as rods, often exhibit large nonlinear geometrical deformations even under moderate external forces (e.g., gravity). This characteristic results in a rich variety of morphological changes, making them appealing for…
Inferring the mechanical properties of soft tissues from measured deformations is a fundamental challenge in elastography. A rarely examined assumption underlying existing approaches is that the assumed constitutive law correctly describes…
This paper presents a novel intersection-based remapping method for isoparametric curvilinear meshes within the indirect arbitrary Lagrangian-Eulerian (ALE) framework, addressing the challenges of transferring physical quantities between…
Inverse problems in statistical physics are motivated by the challenges of `big data' in different fields, in particular high-throughput experiments in biology. In inverse problems, the usual procedure of statistical physics needs to be…
Before septation processes shape its four chambers, the embryonic heart is a straight tube that spontaneously bends and twists breaking the left-right symmetry. In particular, the heart tube is subjected to a cell remodelling inducing…
Vertex Models, as used to describe cellular tissue, have an energy controlled by deviations of each cell area and perimeter from target values. The constrained nonlinear relation between area and perimeter leads to new mechanical response.…
In this paper, we deal with the inverse problem of the shape reconstruction of inclusions in elastic bodies. The main idea of this reconstruction is based on the monotonicity property of the Neumann-to-Dirichlet operator presented in a…
This study proposes an end-to-end unsupervised diffeomorphic deformable registration framework based on moving mesh parameterization. Using this parameterization, a deformation field can be modeled with its transformation Jacobian…