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A tandem cell is proposed for DNA sequencing in which an exonuclease enzyme cleaves bases (mononucleotides) from a strand of DNA for identification inside a nanopore. It has two nanopores and three compartments with the structure [cis1,…

Biomolecules · Quantitative Biology 2014-08-21 G. Sampath

We present a tight-binding model study of a two-terminal graphene nanopore device for sequential determination of DNA bases. Using Green's function technique we investigate the changes in electronic transport properties of the device due to…

Mesoscale and Nanoscale Physics · Physics 2022-06-20 Sourav Kundu , S. N. Karmakar

Porous materials provide a large surface to volume ratio, thereby providing a knob to alter fundamental properties in unprecedented ways. In thermal transport, porous nanomaterials can reduce thermal conductivity by not only enhancing…

There has been tremendous experimental progress in the last decade in identifying the structure and function of biological pores (ion channels) and fabricating synthetic pores. Despite this progress, many questions still remain about the…

Soft Condensed Matter · Physics 2015-03-17 Michael Zwolak , James Wilson , Massimiliano Di Ventra

Polymers are increasingly used in the transport sector due to their many advantages; lightness, corrosion resistance, ease to process... However, most of them have limited mechanical properties. To improve these latter, one of the solutions…

Classical Physics · Physics 2024-04-23 Nicolas Raoux , Abdelkibir Benelfellah , Nourredine Aït Hocine

The simulation of fluid flow in real, multiscale porous media remains challenging due to the complexity of nanoscale phenomena and the difficulty of developing upscaling methodologies. In this study, we introduce a multiscale filtration…

Fluid Dynamics · Physics 2026-05-13 Irina Nesterova , Rustem Sirazov , Aleksey Khlyupin

In nanopore technology, the development of multiplexed detection and release platforms with high spatial and temporal resolution remains a significant challenge due to the difficulty in distinguishing signals originating from different…

Applied Physics · Physics 2025-10-16 Ali Douaki , Shukun Weng , Silvia Dante , Nako Nakatsuka , Makusu Tsutsui , Roman Krahne , Denis Garoli

Understanding the adsorption of water and characterizing the water film formed within nanostructures are essential for advancements in fields such as nanofluidics, water purification, and biosensing devices. In our research, we focus on…

We consider charge transport in nanopores where the dielectric constant inside the nanopore is much greater than in the surrounding material, so that the flux of the electric fields due to the charges is almost entirely confined to the…

Mathematical Physics · Physics 2015-05-18 S. R. Holcombe , E. R. Smith

Resistive random-access memories, also known as memristors, whose resistance can be modulated by the electrically driven formation and disruption of conductive filaments within an insulator, are promising candidates for neuromorphic…

The translocation dynamics of a polymer chain through a nanopore in the absence of an external driving force is analyzed by means of scaling arguments, fractional calculus, and computer simulations. The problem at hand is mapped on a one…

Soft Condensed Matter · Physics 2007-07-29 J. L. A. Dubbeldam , A. Milchev , V. G. Rostiashvili , T. A. Vilgis

In conductor-insulator composites in which the conducting particles are dispersed in an insulating continuous matrix the electrical connectedness is established by interparticle quantum tunneling. A recent formulation of the transport…

Disordered Systems and Neural Networks · Physics 2015-05-20 B. Nigro , G. Ambrosetti , C. Grimaldi , T. Maeder , P. Ryser

We develop a correlation-corrected transport theory in order to predict ionic and polymer transport properties of membrane nanopores in physical conditions where mean-field electrostatics breaks down. The experimentally observed low KCl…

Soft Condensed Matter · Physics 2014-11-06 Sahin Buyukdagli , Tapio Ala-Nissila

We present a complete numerical calculation and an experimental data analysis of the universal conductance fluctuations in quasi-one-dimension nanowires. The conductance peak density model, introduced in nanodevice research on [Phys. Rev.…

Mesoscale and Nanoscale Physics · Physics 2018-10-11 T. Verçosa , Yong-Joo Doh , J. G. G. S. Ramos , A. L. R. Barbosa

Nanoporous materials are of broad interest for various applications, in particular advanced thermoelectric materials. The introduction of nanoscale porosity, even at modest levels, has been known to drastically reduce a materials thermal…

Mesoscale and Nanoscale Physics · Physics 2019-07-31 Laura de Sousa Oliveira , Neophytos Neophytou

The Critical Path Approximation ("CPA") is integrated with a lattice-based approach to percolation to provide a model for conductivity in nanofibre-based composites. Our treatment incorporates a recent estimate for the anisotropy in…

Disordered Systems and Neural Networks · Physics 2015-03-23 Avik P. Chatterjee , Claudio Grimaldi

Heat management is crucial in the design of nanoscale devices as the operating temperature determines their efficiency and lifetime. Past experimental and theoretical works exploring nanoscale heat transport in semiconductors addressed…

We study the motion of dispersed nanoprobes in entangled active-passive polymer mixtures. By comparing the two architectures of linear vs. unconcatenated and unknotted circular polymers, we demonstrate that novel, rich physics emerge. For…

Soft Condensed Matter · Physics 2021-08-27 Andrea Papale , Jan Smrek , Angelo Rosa

The last decade, nanopores have emerged as a new and interesting tool for the study of biological macromolecules like proteins and DNA. While biological pores, especially alpha-hemolysin, have been promising for the detection of DNA, their…

Biological Physics · Physics 2015-03-13 Ronald Kox , Stella Deheryan , Chang Chen , Nima Arjmandi , Liesbet Lagae , Gustaaf Borghs

Nanopores -- nanosized holes that can transport ions and molecules -- are very promising devices for genomic screening, in particular DNA sequencing. Both solid-state and biological pores suffer from the drawback, however, that the channel…