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Nanopores spanning synthetic membranes have been used as key components in proof-of-principle nanofluidic applications, particularly those involving manipulation of biomolecules or sequencing of DNA. The only practical way of manipulating…

Mesoscale and Nanoscale Physics · Physics 2016-09-21 Tom Chou

Proteins are the active working horses in our body. These biomolecules perform all vital cellular functions from DNA replication and general biosynthesis to metabolic signaling and environmental sensing. While static 3D structures are now…

Quantitative Methods · Quantitative Biology 2020-10-16 Sonja Schmid , Cees Dekker

We study voltage driven translocation of a single stranded (ss) DNA through a membrane channel. Our model, based on a master equation (ME) approach, investigates the probability density function (pdf) of the translocation times, and shows…

Statistical Mechanics · Physics 2007-05-23 O. Flomenbom , J. Klafter

Liquids under confinement differ in behavior from their bulk counterparts and can acquire properties that are specific to the confined phase and linked to the nature and structure of the host matrix. While confined liquid water is not a new…

Materials Science · Physics 2020-07-22 François-Xavier Coudert

We report experimental evidence of surface dominated transport in single crystalline nanoflake devices of topological insulator Bi1.5Sb0.5Te1.8Se1.2. The resistivity measurements show dramatic difference between the nanoflake devices and…

Mesoscale and Nanoscale Physics · Physics 2015-06-04 Bin Xia , Peng Ren , Azat Sulaev , Peng Liu , Shun-Qing Shen , Lan Wang

Continuum simulation is employed to study ion transport and fluid flow through a nanopore in a solid-state membrane under an applied potential drop. Results show the existence of concentration polarization layers on the surfaces of the…

Fluid Dynamics · Physics 2015-06-16 Mao Mao , Sandip Ghosal , Guohui Hu

Extracting the sequence information of DNA from the blocked ionic current is the crucial step of the ionic current-based nanopore sequencing approaches. The thinnest graphene nanopore, which contained only one layer of carbon atoms,…

Biological Physics · Physics 2014-01-29 Wenping Lv , Ren'an Wu

Weak interactions form the core basis of a vast number of biological processes, in particular, those involving intrinsically disordered proteins. Here, we establish a new technique capable of probing these weak interactions between…

Biological Physics · Physics 2019-10-02 Indrani Chakraborty , Gil Rahamim , Ram Avinery , Yael Roichman , Roy Beck

We develop a theory of charge storage in ultra-narrow slit-like pores of nano\-structured electrodes. Our analysis is based on the Blume-Capel model in external field, which we solve analytically on a Bethe lattice. The obtained solutions…

Soft Condensed Matter · Physics 2020-01-08 Maxym Dudka , Svyatoslav Kondrat , Olivier Bénichou , Alexei A. Kornyshev , Gleb Oshanin

Translocation event detection from raw nanopore current signals is a fundamental step in nanopore signal analysis. Traditional data analysis methods rely on user-defined parameters to extract event information, making the interpretation of…

Signal Processing · Electrical Eng. & Systems 2025-04-09 Jaise Johnson , Chinmayi R Galigekere , Manoj M Varma

We employ a three-dimensional molecular dynamics to simulate translocation of a polymer through a nanopore driven by an external force. The translocation is investigated for different three pore diameter and two different external forces.…

Computational Physics · Physics 2019-12-03 Mohammadreza Niknam Hamidabad , Rouhollah Haji Abdolvahab

Existing scalable superconducting quantum processors have only nearest-neighbor coupling. This leads to reduced circuit depth, requiring large series of gates to perform an arbitrary unitary operation in such systems. Recently, multi-modal…

Three-dimensional topological insulators host surface states with linear dispersion, which manifest as a Dirac cone. Nanoscale transport measurements provide direct access to the transport properties of the Dirac cone in real space and…

The unknown quantum electronic conductance across nanojunctions made of silicon-doped carbon wires between carbon leads is investigated. This is done by an appropriate generalization of the phase field matching theory for the…

Mesoscale and Nanoscale Physics · Physics 2015-02-02 D. Szczȩśniak , A. Khater , Z. Bąk , R. Szczȩśniak , M. Abou Ghantous

In this study, using nonequilibrium molecular dynamics simulation, the water flow in carbon nanocones is studied using the TIP4P/2005 rigid water model. The results demonstrate a nonuniform dependence of the flow on the cone apex angle and…

The potential of a double nanopore system to determine DNA barcodes has been demonstrated experimentally. By carrying out Brownian dynamics simulation on a coarse-grained model DNA with protein tag (barcodes) at known locations along the…

Soft Condensed Matter · Physics 2021-02-10 Swarnadeep Seth , Aniket Bhattacharya

The fabrication of nanopores in atomically-thin graphene has recently been achieved and translocation of DNA has been demonstrated. Taken together with an earlier proposal to use graphene nanogaps for the purpose of DNA sequencing, this…

Instrumentation and Detectors · Physics 2011-05-16 Jariyanee Prasongkit , Anton Grigoriev , Biswarup Pathak , Rajeev Ahuja , Ralph H. Scheicher

In the emerging field of DNA storage, data is encoded as DNA sequences and stored. The data is read out again by sequencing the stored DNA. Nanopore sequencing is a new sequencing technology that has many advantages over other methods; in…

Information Theory · Computer Science 2021-02-04 Reyna Hulett , Shubham Chandak , Mary Wootters

Electrical conductivity is the most fundamental charge transport parameter, and measurements of conductivity are a basic part of materials characterization for nearly all conducting materials. In thin films, conductivity is often measured…

Materials Science · Physics 2026-02-05 Yongyi Gao , Hio-Ieng Un , Yuxuan Huang , Henning Sirringhaus , Ian E. Jacobs

We explore the structural properties of anomalous fluids confined in a nanopore using Molecular Dynamics simulations. The fluid is modeled by core-softened (CS) potentials that have a repulsive shoulder and an attractive well at a further…

Soft Condensed Matter · Physics 2014-10-22 Leandro B. Krott , José Rafael Bordin , Marcia Barbosa
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