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Large language models (LLMs) have rapidly improved text embeddings for a growing array of natural-language processing tasks. However, their opaqueness and proliferation into scientific domains such as neuroscience have created a growing…

Computation and Language · Computer Science 2024-05-28 Vinamra Benara , Chandan Singh , John X. Morris , Richard Antonello , Ion Stoica , Alexander G. Huth , Jianfeng Gao

This project investigates the efficacy of Large Language Models (LLMs) in understanding and extracting scientific knowledge across specific domains and to create a deep learning framework: Knowledge AI. As a part of this framework, we…

Computation and Language · Computer Science 2024-08-12 Balaji Muralidharan , Hayden Beadles , Reza Marzban , Kalyan Sashank Mupparaju

Proteins, essential to biological systems, perform functions intricately linked to their three-dimensional structures. Understanding the relationship between protein structures and their amino acid sequences remains a core challenge in…

Quantitative Methods · Quantitative Biology 2024-11-04 Liang He , Peiran Jin , Yaosen Min , Shufang Xie , Lijun Wu , Tao Qin , Xiaozhuan Liang , Kaiyuan Gao , Yuliang Jiang , Tie-Yan Liu

Large language models (LLMs) have learned vast amounts of factual knowledge through self-supervised pre-training on large-scale corpora. Meanwhile, LLMs have also demonstrated excellent multilingual capabilities, which can express the…

Computation and Language · Computer Science 2024-11-27 Pengfei Cao , Yuheng Chen , Zhuoran Jin , Yubo Chen , Kang Liu , Jun Zhao

Language models often pre-train on large unsupervised text corpora, then fine-tune on additional task-specific data. However, typical fine-tuning schemes do not prioritize the examples that they tune on. We show that, if you can prioritize…

Computation and Language · Computer Science 2023-05-12 Ian Osband , Seyed Mohammad Asghari , Benjamin Van Roy , Nat McAleese , John Aslanides , Geoffrey Irving

Protein is linked to almost every life process. Therefore, analyzing the biological structure and property of protein sequences is critical to the exploration of life, as well as disease detection and drug discovery. Traditional protein…

Machine Learning · Computer Science 2021-12-08 Yijia Xiao , Jiezhong Qiu , Ziang Li , Chang-Yu Hsieh , Jie Tang

Pretrained language models (PLMs) form the basis of most state-of-the-art NLP technologies. Nevertheless, they are essentially black boxes: Humans do not have a clear understanding of what knowledge is encoded in different parts of the…

Computation and Language · Computer Science 2023-11-15 Tanja Baeumel , Soniya Vijayakumar , Josef van Genabith , Guenter Neumann , Simon Ostermann

We consider probabilistic topic models and more recent word embedding techniques from a perspective of learning hidden semantic representations. Inspired by a striking similarity of the two approaches, we merge them and learn probabilistic…

Computation and Language · Computer Science 2017-11-15 Anna Potapenko , Artem Popov , Konstantin Vorontsov

Representation learning and \emph{de novo} generation of proteins are pivotal computational biology tasks. Whilst natural language processing (NLP) techniques have proven highly effective for protein sequence modelling, structure modelling…

Quantitative Methods · Quantitative Biology 2025-01-08 Benoit Gaujac , Jérémie Donà , Liviu Copoiu , Timothy Atkinson , Thomas Pierrot , Thomas D. Barrett

Machine comprehension(MC) style question answering is a representative problem in natural language processing. Previous methods rarely spend time on the improvement of encoding layer, especially the embedding of syntactic information and…

Artificial Intelligence · Computer Science 2017-07-31 Boyuan Pan , Hao Li , Zhou Zhao , Bin Cao , Deng Cai , Xiaofei He

Understanding what knowledge is implicitly encoded in deep learning models is essential for improving the interpretability of AI systems. This paper examines common methods to explain the knowledge encoded in word embeddings, which are core…

Computation and Language · Computer Science 2025-08-20 Hanna Herasimchyk , Alhassan Abdelhalim , Sören Laue , Michaela Regneri

Many contextualized word representations are now learned by intricate neural network models, such as masked neural language models (MNLMs) which are made up of huge neural network structures and trained to restore the masked text. Such…

Computation and Language · Computer Science 2022-09-02 Sunjae Kwon , Cheongwoong Kang , Jiyeon Han , Jaesik Choi

Answering compositional questions that require multiple steps of reasoning against text is challenging, especially when they involve discrete, symbolic operations. Neural module networks (NMNs) learn to parse such questions as executable…

Computation and Language · Computer Science 2020-02-18 Nitish Gupta , Kevin Lin , Dan Roth , Sameer Singh , Matt Gardner

Deep neural networks are inherently opaque and challenging to interpret. Unlike hand-crafted feature-based models, we struggle to comprehend the concepts learned and how they interact within these models. This understanding is crucial not…

Computation and Language · Computer Science 2023-07-12 Shammur Absar Chowdhury , Nadir Durrani , Ahmed Ali

The trade-off between predictive accuracy and data availability makes it difficult to predict protein--protein binding affinity accurately. The lack of experimentally resolved protein structures limits the performance of structure-based…

Machine Learning · Computer Science 2026-01-08 Wajid Arshad Abbasi , Syed Ali Abbas , Maryum Bibi , Saiqa Andleeb , Muhammad Naveed Akhtar

Protein language models (PLMs) have shown promise in improving the understanding of protein sequences, contributing to advances in areas such as function prediction and protein engineering. However, training these models from scratch…

Machine Learning · Computer Science 2024-12-19 Shivasankaran Vanaja Pandi , Bharath Ramsundar

When analyzing the genome, researchers have discovered that proteins bind to DNA based on certain patterns of the DNA sequence known as "motifs". However, it is difficult to manually construct motifs due to their complexity. Recently,…

Machine Learning · Computer Science 2017-02-23 Jack Lanchantin , Ritambhara Singh , Yanjun Qi

The state-of-the-art CNN models give good performance on sentence classification tasks. The purpose of this work is to empirically study desirable properties such as semantic coherence, attention mechanism and reusability of CNNs in these…

Computation and Language · Computer Science 2016-10-11 Madhusudan Lakshmana , Sundararajan Sellamanickam , Shirish Shevade , Keerthi Selvaraj

Pre-trained language models have been found to capture a surprisingly rich amount of lexical knowledge, ranging from commonsense properties of everyday concepts to detailed factual knowledge about named entities. Among others, this makes it…

Computation and Language · Computer Science 2022-09-12 Asahi Ushio , Jose Camacho-Collados , Steven Schockaert

Current language models have a significant limitation in the ability to encode and decode factual knowledge. This is mainly because they acquire such knowledge from statistical co-occurrences although most of the knowledge words are rarely…

Computation and Language · Computer Science 2017-03-03 Sungjin Ahn , Heeyoul Choi , Tanel Pärnamaa , Yoshua Bengio