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Survival modeling in healthcare relies on explainable statistical models; yet, their underlying assumptions are often simplistic and, thus, unrealistic. Machine learning models can estimate more complex relationships and lead to more…

Unsupervised learning of disease subtypes from multi-omics data presents a significant opportunity for advancing personalized medicine. We introduce OmicsCL, a modular contrastive learning framework that jointly embeds heterogeneous omics…

Machine Learning · Computer Science 2025-05-02 Atahan Karagoz

Contrastive learning is widely used for recommendation model learning, where selecting representative and informative negative samples is critical. Existing methods usually focus on centralized data, where abundant and high-quality negative…

Machine Learning · Computer Science 2022-04-22 Chuhan Wu , Fangzhao Wu , Tao Qi , Yongfeng Huang , Xing Xie

Electronic health record (EHR) data is collected by individual institutions and often stored across locations in silos. Getting access to these data is difficult and slow due to security, privacy, regulatory, and operational issues. We…

Computers and Society · Computer Science 2018-12-04 Dianbo Liu , Timothy Miller , Raheel Sayeed , Kenneth D. Mandl

Early warning of intraoperative adverse events plays a vital role in reducing surgical risk and improving patient safety. While deep learning has shown promise in predicting the single adverse event, several key challenges remain:…

Machine Learning · Computer Science 2026-04-28 Xueyao Wang , Xiuding Cai , Honglin Shang , Yaoyao Zhu , Yu Yao

Obtaining labelled ECG data for developing supervised models is challenging. Contrastive learning (CL) has emerged as a promising pretraining approach that enables effective transfer learning with limited labelled data. However, existing CL…

Machine Learning · Computer Science 2026-01-23 Muhammad Ilham Rizqyawan , Peter Macfarlane , Stathis Hadjidemetriou , Fani Deligianni

Reconstructing a 12-lead electrocardiogram (ECG) from a reduced lead set is an ill-posed inverse problem due to anatomical variability. Standard deep learning methods often ignore underlying cardiac pathology losing vital morphology in…

Machine Learning · Computer Science 2026-03-19 Youssef Youssef , Jitin Singla

As clinical data are becoming increasingly available, machine learning methods have been employed to extract knowledge from them and predict clinical events. While promising, approaches suffer from at least two main issues: low availability…

Reliability of deep learning models is critical for deployment in high-stakes applications, where out-of-distribution or adversarial inputs may lead to detrimental outcomes. Evidential Deep Learning, an efficient paradigm for uncertainty…

Machine Learning · Computer Science 2026-03-05 Charmaine Barker , Daniel Bethell , Simos Gerasimou

The wide adoption of Electronic Health Records (EHR) has resulted in large amounts of clinical data becoming available, which promises to support service delivery and advance clinical and informatics research. Deep learning techniques have…

Machine Learning · Computer Science 2022-02-14 Thanh Nguyen-Duc , Natasha Mulligan , Gurdeep S. Mannu , Joao H. Bettencourt-Silva

Continual learning, the ability of a model to learn over time without forgetting previous knowledge and, therefore, be adaptive to new data, is paramount in dynamic fields such as disease outbreak prediction. Deep neural networks, i.e.,…

Machine Learning · Computer Science 2024-01-18 Saba Aslam , Abdur Rasool , Hongyan Wu , Xiaoli Li

The breadth, scale, and temporal granularity of modern electronic health records (EHR) systems offers great potential for estimating personalized and contextual patient health trajectories using sequential deep learning. However, learning…

Recent advances in large language models (LLMs) have enabled the development of multimodal medical AI. While models such as MedGemini achieve high accuracy on VQA tasks like USMLE MM, their performance on ECG based tasks remains limited,…

Machine Learning · Computer Science 2026-02-12 Junichiro Takahashi , Masataka Sato , Satoshi Kodeta , Norihiko Takeda

The timeliness of detection of a sepsis event in progress is a crucial factor in the outcome for the patient. Machine learning models built from data in electronic health records can be used as an effective tool for improving this…

The early detection of anomalous events in time series data is essential in many domains of application. In this paper we deal with critical health events, which represent a significant cause of mortality in intensive care units of…

Machine Learning · Statistics 2020-10-23 Vitor Cerqueira , Luis Torgo , Carlos Soares

An important issue in joint modelling for outcomes and longitudinal risk factors in cohort studies is to have an accurate assessment of events. Events determined based on ICD-9 codes can be very inaccurate, in particular for cardiovascular…

Methodology · Statistics 2025-06-25 Mirajul Islam , Michael J. Daniels , Donald Lloyd-Jones , Juned Siddique

In realistic scenarios, multivariate timeseries evolve over case-by-case time-scales. This is particularly clear in medicine, where the rate of clinical events varies by ward, patient, and application. Increasingly complex models have been…

Machine Learning · Computer Science 2020-03-06 Jacob Deasy , Ari Ercole , Pietro Liò

Electronic Health Records (EHR) data contains medical records such as diagnoses, medications, procedures, and treatments of patients. This data is often considered sensitive medical information. Therefore, the EHR data from the medical…

Machine Learning · Computer Science 2023-05-25 Ofir Ben Shoham , Nadav Rappoport

Temporal knowledge graph, serving as an effective way to store and model dynamic relations, shows promising prospects in event forecasting. However, most temporal knowledge graph reasoning methods are highly dependent on the recurrence or…

Artificial Intelligence · Computer Science 2022-12-05 Yi Xu , Junjie Ou , Hui Xu , Luoyi Fu

The increasing volume of electronic health records (EHRs) presents the opportunity to improve the accuracy and robustness of models in clinical prediction tasks. Unlike traditional centralized approaches, federated learning enables training…

Machine Learning · Computer Science 2026-01-30 Jiyoun Kim , Junu Kim , Kyunghoon Hur , Edward Choi
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