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Optical coherence tomography (OCT) is a noninvasive imaging modality which can be used to obtain depth images of the retina. The changing layer thicknesses can thus be quantified by analyzing these OCT images, moreover these changes have…

Computer Vision and Pattern Recognition · Computer Science 2018-03-15 Yufan He , Aaron Carass , Bruno M. Jedynak , Sharon D. Solomon , Shiv Saidha , Peter A. Calabresi , Jerry L. Prince

Optical coherence tomography (OCT) is used for non-invasive diagnosis of diabetic macular edema assessing the retinal layers. In this paper, we propose a new fully convolutional deep architecture, termed ReLayNet, for end-to-end…

Computer Vision and Pattern Recognition · Computer Science 2017-07-10 Abhijit Guha Roy , Sailesh Conjeti , Sri Phani Krishna Karri , Debdoot Sheet , Amin Katouzian , Christian Wachinger , Nassir Navab

Alterations in retinal layer thickness, measurable using Optical Coherence Tomography (OCT), have been associated with neurodegenerative diseases such as Alzheimer's disease (AD). While previous studies have mainly focused on segmented…

Computer Vision and Pattern Recognition · Computer Science 2025-11-10 Yasemin Turkan , F. Boray Tek , M. Serdar Nazlı , Öykü Eren

Optical coherence tomography (OCT) uses low-coherence reflectometry to obtain cross-sectional images of inhomogeneous media, such as biological tissue. OCT is particularly useful in the biomedical ea, since the imaging can be performed…

Medical Physics · Physics 2018-03-01 Takahisa Mitsui , Kenichiro Aoki

Purpose: We proposed a deep convolutional neural network (CNN), named Retinal Fluid Segmentation Network (ReF-Net) to segment volumetric retinal fluid on optical coherence tomography (OCT) volume. Methods: 3 x 3-mm OCT scans were acquired…

Image and Video Processing · Electrical Eng. & Systems 2020-10-28 Yukun Guo , Tristan T. Hormel , Honglian Xiong , Jie Wang , Thomas S. Hwang , Yali Jia

Retinal Optical Coherence Tomography (OCT), a noninvasive cross-sectional scan of the eye with qualitative 3D visualization of the retinal anatomy is use to study the retinal structure and the presence of pathogens. The advent of the…

Image and Video Processing · Electrical Eng. & Systems 2023-02-28 Nchongmaje Ndipenoch , Alina Miron , Zidong Wang , Yongmin Li

Optical coherence tomography angiography (OCTA) is a noninvasive imaging technique that can reveal high-resolution retinal vessels. In this work, we propose an accurate and efficient neural network for retinal vessel segmentation in OCTA…

Image and Video Processing · Electrical Eng. & Systems 2023-09-19 Haojian Ning , Chengliang Wang , Xinrun Chen , Shiying Li

Optical coherence tomography (OCT) is widely used for diagnosing and monitoring retinal diseases, such as age-related macular degeneration (AMD). The segmentation of biomarkers such as layers and lesions is essential for patient diagnosis…

Computer Vision and Pattern Recognition · Computer Science 2025-09-26 Botond Fazekas , Guilherme Aresta , Philipp Seeböck , Julia Mai , Ursula Schmidt-Erfurth , Hrvoje Bogunović

Early identification of patients at risk of cardiovascular diseases (CVD) is crucial for effective preventive care, reducing healthcare burden, and improving patients' quality of life. This study demonstrates the potential of retinal…

Image and Video Processing · Electrical Eng. & Systems 2024-10-21 Cynthia Maldonado-Garcia , Arezoo Zakeri , Alejandro F Frangi , Nishant Ravikumar

Early and accurate classification of retinal diseases is critical to counter vision loss and for guiding clinical management of retinal diseases. In this study, we proposed a deep learning method for retinal disease classification utilizing…

Computer Vision and Pattern Recognition · Computer Science 2026-02-24 Mohammad Tahmid Noor , Shayan Abrar , Jannatul Adan Mahi , Md Parvez Mia , Asaduzzaman Hridoy , Samanta Ghosh

Optical coherence tomography angiography (OCTA) is a novel imaging modality that has been widely utilized in ophthalmology and neuroscience studies to observe retinal vessels and microvascular systems. However, publicly available OCTA…

Image and Video Processing · Electrical Eng. & Systems 2022-12-27 Mingchao Li , Kun Huang , Qiuzhuo Xu , Jiadong Yang , Yuhan Zhang , Zexuan Ji , Keren Xie , Songtao Yuan , Qinghuai Liu , Qiang Chen

Purpose: To test the feasibility of using deep learning for optical coherence tomography angiography (OCTA) detection of diabetic retinopathy (DR). Methods: A deep learning convolutional neural network (CNN) architecture VGG16 was employed…

Quantitative Methods · Quantitative Biology 2021-12-16 David Le , Minhaj Alam , Cham Yao , Jennifer I. Lim , R. V. P. Chan , Devrim Toslak , Xincheng Yao

Despite significant advances in artificial intelligence (AI) for computer vision, its application in medical imaging has been limited by the burden and limits of expert-generated labels. We used images from optical coherence tomography…

Computer Vision and Pattern Recognition · Computer Science 2018-02-27 Cecilia S. Lee , Ariel J. Tyring , Yue Wu , Sa Xiao , Ariel S. Rokem , Nicolaas P. Deruyter , Qinqin Zhang , Adnan Tufail , Ruikang K. Wang , Aaron Y. Lee

Objective: Optical coherence tomography (OCT) and its angiography (OCTA) have several advantages for the early detection and diagnosis of diabetic retinopathy (DR). However, automated, complete DR classification frameworks based on both OCT…

Image and Video Processing · Electrical Eng. & Systems 2020-09-28 Pengxiao Zang , Liqin Gao , Tristan T. Hormel , Jie Wang , Qisheng You , Thomas S. Hwang , Yali Jia

Optical coherence tomography angiography (OCTA) is a non-invasive imaging modality that can acquire high-resolution volumes of the retinal vasculature and aid the diagnosis of ocular, neurological and cardiac diseases. Segmenting the…

Diagnosing different retinal diseases from Spectral Domain Optical Coherence Tomography (SD-OCT) images is a challenging task. Different automated approaches such as image processing, machine learning and deep learning algorithms have been…

Image and Video Processing · Electrical Eng. & Systems 2020-05-19 Sharif Amit Kamran , Sourajit Saha , Ali Shihab Sabbir , Alireza Tavakkoli

According to the World Health Organization, 285 million people worldwide live with visual impairment. The most commonly used imaging technique for diagnosis in ophthalmology is optical coherence tomography (OCT). However, analysis of…

Computer Vision and Pattern Recognition · Computer Science 2019-04-02 Max-Heinrich Laves , Sontje Ihler , Lüder A. Kahrs , Tobias Ortmaier

Segmentation of retinal layers from Optical Coherence Tomography (OCT) volumes is a fundamental problem for any computer aided diagnostic algorithm development. This requires preprocessing steps such as denoising, region of interest…

Computer Vision and Pattern Recognition · Computer Science 2018-06-26 Karthik Gopinath , Samrudhdhi B Rangrej , Jayanthi Sivaswamy

Since the introduction of optical coherence tomography (OCT), it has been possible to study the complex 3D morphological changes of the optic nerve head (ONH) tissues that occur along with the progression of glaucoma. Although several deep…

We present a cascade deep neural network to segment retinal vessels in volumetric optical coherence tomography (OCT). Two types of knowledge are infused into the network for confining the searching regions. (1) Histology. The retinal…

Image and Video Processing · Electrical Eng. & Systems 2019-10-22 Liyang Fang , Jianlong Yang , Lei Mou , Huihong Zhang , Zhenjie Chai , Zhi Chen , Jiang Liu