Related papers: Optical time-harmonic elastography for multiscale …
Elasticity is a fundamental cellular property that is related to the anatomy, functionality and pathological state of cells and tissues. However, current techniques based on cell deformation, atomic force microscopy or Brillouin scattering…
Visualizing elastic waves by noninvasive imaging has been useful for analyzing the mechanical properties of materials and tissues. However, the maximum wave frequency of elastography has been limited to ~10 kHz due to the finite sensitivity…
Traveling-wave optical coherence elastography (OCE) is a promising technique to measure the stiffness of biological tissues. While OCE has been applied to relatively homogeneous samples, tissues with significantly varying elasticity through…
Dynamic optical coherence elastography (OCE) tracks mechanical wave propagation in the subsurface region of tissue to image its shear modulus. For bulk shear waves, the lateral resolution of the reconstructed modulus map (i.e.,…
We provide a mathematical analysis of and a numerical framework for full-field optical coherence elastography, which has unique features including micron-scale resolution, real-time processing, and non-invasive imaging. We develop a novel…
Tissue stiffness is related to soft tissue pathologies and can be assessed through palpation or via clinical imaging systems, e.g., ultrasound or magnetic resonance imaging. Typically, the image based approaches are not suitable during…
Objective: The mechanical properties of corneal tissues play a crucial role in determining corneal shape and have significant implications in vision care. This study aimed to address the challenge of obtaining accurate in vivo data for the…
Mechanical properties of tissue provide valuable information for identifying lesions. One approach to obtain quantitative estimates of elastic properties is shear wave elastography with optical coherence elastography (OCE). However, given…
Ultrasound shear wave elastography (SWE) is a noninvasive way to measure stiffness of soft tissue for medical diagnosis. In SWE imaging, an acoustic radiation force induces tissue displacement, which creates shear waves (SWs) that travel…
It is known that changes in the mechanical properties of tissues are associated with the onset and progression of certain diseases. Ultrasound elastography is a technique to characterize tissue stiffness using ultrasound imaging either by…
Optical coherence elastography (OCE) is a powerful non-invasive imaging technique for high-resolution assessment of tissue elasticity and viscoelasticity. Accurate characterization of viscoelastic properties requires estimating shear wave…
Objective - Shear wave elastography has enriched ultrasound medical imaging with quantitative measurements of tissue stiffness. However, this method still suffers from some limitations due to viscoelasticity, guiding geometry or static…
Robot-assisted surgery has advantages compared to conventional laparoscopic procedures, e.g., precise movement of the surgical instruments, improved dexterity, and high-resolution visualization of the surgical field. However, mechanical…
The mechanical properties of arterial walls are critical for maintaining vascular function under pulsatile pressure and are closely linked to the development of cardiovascular diseases. Despite advances in imaging and elastography,…
Optical coherence elastography allows the characterization of the mechanical properties of tissues, and can be performed through estimating local displacement maps from subsequent acquisitions of a sample under different loads. This…
Optical Coherence Tomography (OCT) has become an indispensable tool for investigating mesoscopic features in soft matter and fluid mechanics. Its ability to provide high-resolution, non-invasive measurements in both spatial and temporal…
Shear-wave elastography (SWE) permits local estimation of tissue elasticity, an important imaging marker in biomedicine. This recently-developed, advanced technique assesses the speed of a laterally-travelling shear wave after an acoustic…
Topology optimization (TO) has experienced a dramatic development over the last decades aided by the arising of metamaterials and additive manufacturing (AM) techniques, and it is intended to achieve the current and future challenges. In…
As disease often alters the structural properties of soft tissue, noninvasive elastography techniques have emerged to quantitatively assess in vivo mechanical properties. Magnetic Resonance Elastography (MRE) based on dynamic deformations…
Displacement estimation in optical coherence tomography (OCT) imaging is relevant for several potential applications, e.g. for optical coherence elastography (OCE) for corneal biomechanical characterization. Larger displacements may be…