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Multi-contrast magnetic resonance imaging (MRI) is the most common management tool used to characterize neurological disorders based on brain tissue contrasts. However, acquiring high-resolution MRI scans is time-consuming and infeasible…

Image and Video Processing · Electrical Eng. & Systems 2023-06-08 Ye Mao , Lan Jiang , Xi Chen , Chao Li

Anomaly detection in tabular data remains challenging due to complex feature interactions and the scarcity of anomalous examples. Denoising autoencoders rely on fixed-magnitude noise, limiting adaptability to diverse data distributions.…

Machine Learning · Computer Science 2025-08-04 Timur Sattarov , Marco Schreyer , Damian Borth

Our hypothesis is that UDA using diffusion-weighted images, generated with a unified model, offers a promising and reliable strategy for enhancing the performance of supervised learning models in multi-site prostate lesion detection,…

Denoising diffusion models offer a promising approach to accelerating magnetic resonance imaging (MRI) and producing diagnostic-level images in an unsupervised manner. However, our study demonstrates that even tiny worst-case potential…

Image and Video Processing · Electrical Eng. & Systems 2024-06-26 Tianyu Han , Sven Nebelung , Firas Khader , Jakob Nikolas Kather , Daniel Truhn

Denoising diffusion models have recently achieved remarkable success in image generation, capturing rich information about natural image statistics. This makes them highly promising for image reconstruction, where the goal is to recover a…

Computer Vision and Pattern Recognition · Computer Science 2025-09-09 Shady Abu-Hussein , Tom Tirer , Raja Giryes

Unsupervised anomaly detection (UAD) is a key ingredient of automated visual inspection in modern manufacturing. The reconstruction-based methods appeal because they have basic architectural design and they process data quickly but they…

Computer Vision and Pattern Recognition · Computer Science 2026-02-03 Dmytro Filatov , Valentyn Fedorov , Vira Filatova , Andrii Zelenchuk

Unsupervised anomaly detection (UAD) alleviates large labeling efforts by training exclusively on unlabeled in-distribution data and detecting outliers as anomalies. Generally, the assumption prevails that large training datasets allow the…

Computer Vision and Pattern Recognition · Computer Science 2024-10-29 Felix Meissen , Johannes Getzner , Alexander Ziller , Özgün Turgut , Georgios Kaissis , Martin J. Menten , Daniel Rueckert

Tables are an abundant form of data with use cases across all scientific fields. Real-world datasets often contain anomalous samples that can negatively affect downstream analysis. In this work, we only assume access to contaminated data…

Machine Learning · Computer Science 2023-07-25 Guy Zamberg , Moshe Salhov , Ofir Lindenbaum , Amir Averbuch

Learning-based image reconstruction models, such as those based on the U-Net, require a large set of labeled images if good generalization is to be guaranteed. In some imaging domains, however, labeled data with pixel- or voxel-level label…

Image and Video Processing · Electrical Eng. & Systems 2024-01-08 Sean I. Young , Adrian V. Dalca , Enzo Ferrante , Polina Golland , Christopher A. Metzler , Bruce Fischl , Juan Eugenio Iglesias

Out-of-distribution (OOD) detection is essential to improve the reliability of machine learning models by detecting samples that do not belong to the training distribution. Detecting OOD samples effectively in certain tasks can pose a…

Computer Vision and Pattern Recognition · Computer Science 2023-11-02 Divyanshu Mishra , He Zhao , Pramit Saha , Aris T. Papageorghiou , J. Alison Noble

Pathological brain appearances may be so heterogeneous as to be intelligible only as anomalies, defined by their deviation from normality rather than any specific pathological characteristic. Amongst the hardest tasks in medical imaging,…

Image and Video Processing · Electrical Eng. & Systems 2021-02-24 Walter Hugo Lopez Pinaya , Petru-Daniel Tudosiu , Robert Gray , Geraint Rees , Parashkev Nachev , Sebastien Ourselin , M. Jorge Cardoso

Magnetic resonance imaging (MRI), especially functional MRI (fMRI) and diffusion MRI (dMRI), is essential for studying neurodegenerative diseases. However, missing modalities pose a major barrier to their clinical use. Although GAN- and…

Computer Vision and Pattern Recognition · Computer Science 2025-11-10 Xiongri Shen , Jiaqi Wang , Yi Zhong , Zhenxi Song , Leilei Zhao , Yichen Wei , Lingyan Liang , Shuqiang Wang , Baiying Lei , Demao Deng , Zhiguo Zhang

The primary goal of this work is to study the effectiveness of an unsupervised domain adaptation approach for various applications such as binary classification and anomaly detection in the context of Alzheimer's disease (AD) detection for…

Image and Video Processing · Electrical Eng. & Systems 2022-12-27 Pranath Reddy

We tackle unsupervised anomaly detection (UAD), a problem of detecting data that significantly differ from normal data. UAD is typically solved by using density estimation. Recently, deep neural network (DNN)-based density estimators, such…

Machine Learning · Statistics 2019-03-14 Masataka Yamaguchi , Yuma Koizumi , Noboru Harada

Unsupervised anomaly detection methods offer a promising and flexible alternative to supervised approaches, holding the potential to revolutionize medical scan analysis and enhance diagnostic performance. In the current landscape, it is…

Image and Video Processing · Electrical Eng. & Systems 2023-08-29 Cosmin I. Bercea , Esther Puyol-Antón , Benedikt Wiestler , Daniel Rueckert , Julia A. Schnabel , Andrew P. King

Deep learning is widely applied in computer-aided pathological diagnosis, which alleviates the pathologist workload and provide timely clinical analysis. However, most models generally require large-scale annotated data for training, which…

Computer Vision and Pattern Recognition · Computer Science 2024-03-12 Zeyu Liu , Tianyi Zhang , Yufang He , Yunlu Feng , Yu Zhao , Guanglei Zhang

At the core of both successful generative and self-supervised representation learning models there is a reconstruction objective that incorporates some form of image corruption. Diffusion models implement this approach through a scheduled…

Computer Vision and Pattern Recognition · Computer Science 2024-06-26 Philippe Hansen-Estruch , Sriram Vishwanath , Amy Zhang , Manan Tomar

Inverse problems, such as accelerated MRI reconstruction, are ill-posed and an infinite amount of possible and plausible solutions exist. This may not only lead to uncertainty in the reconstructed image but also in downstream tasks such as…

Image and Video Processing · Electrical Eng. & Systems 2024-07-26 Jan Nikolas Morshuis , Matthias Hein , Christian F. Baumgartner

Deep learning models in medical imaging often encounter challenges when adapting to new clinical settings unseen during training. Test-time adaptation offers a promising approach to optimize models for these unseen domains, yet its…

Machine Learning · Computer Science 2024-10-28 Sameer Ambekar , Julia A. Schnabel , Cosmin I. Bercea

Image reconstruction from radio-frequency data is pivotal in ultrafast plane wave ultrasound imaging. Unlike the conventional delay-and-sum (DAS) technique, which relies on somewhat imprecise assumptions, deep learning-based methods perform…

Computer Vision and Pattern Recognition · Computer Science 2023-12-18 Hengrong Lan , Zhiqiang Li , Qiong He , Jianwen Luo