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Generating synthetic Computed Tomography (CT) images from Cone Beam Computed Tomography (CBCT) is desirable for improving the image quality of CBCT. Existing synthetic CT (sCT) generation methods using Convolutional Neural Networks (CNN)…

Image and Video Processing · Electrical Eng. & Systems 2025-01-14 Xianhao Zhou , Jianghao Wu , Huangxuan Zhao , Lei Chen , Shaoting Zhang , Guotai Wang

As a means to extract biomarkers from medical imaging, radiomics has attracted increased attention from researchers. However, reproducibility and performance of radiomics in low dose CT scans are still poor, mostly due to noise. Deep…

Quantitative Methods · Quantitative Biology 2021-09-17 Junhua Chen , Leonard Wee , Andre Dekker , Inigo Bermejo

With the advent of Deep Learning (DL) techniques, especially Generative Adversarial Networks (GANs), data augmentation and generation are quickly evolving domains that have raised much interest recently. However, the DL techniques are data…

Computer Vision and Pattern Recognition · Computer Science 2018-05-30 Umair Javaid , John A. Lee

In the field of radiotherapy, accurate imaging and image registration are of utmost importance for precise treatment planning. Magnetic Resonance Imaging (MRI) offers detailed imaging without being invasive and excels in soft-tissue…

Image and Video Processing · Electrical Eng. & Systems 2023-11-29 Saba Nikbakhsh , Lachin Naghashyar , Morteza Valizadeh , Mehdi Chehel Amirani

Computed tomography (CT) is critical for various clinical applications, e.g., radiotherapy treatment planning and also PET attenuation correction. However, CT exposes radiation during acquisition, which may cause side effects to patients.…

Computer Vision and Pattern Recognition · Computer Science 2016-12-19 Dong Nie , Roger Trullo , Caroline Petitjean , Su Ruan , Dinggang Shen

The generation of Synthetic Computed Tomography (sCT) images has become a pivotal methodology in modern clinical practice, particularly in the context of Radiotherapy (RT) treatment planning. The use of sCT enables the calculation of doses,…

Diversity in data is critical for the successful training of deep learning models. Leveraged by a recurrent generative adversarial network, we propose the CT-SGAN model that generates large-scale 3D synthetic CT-scan volumes ($\geq…

Image and Video Processing · Electrical Eng. & Systems 2021-11-08 Ahmad Pesaranghader , Yiping Wang , Mohammad Havaei

Most of the Deep Neural Networks (DNNs) based CT image denoising literature shows that DNNs outperform traditional iterative methods in terms of metrics such as the RMSE, the PSNR and the SSIM. In many instances, using the same metrics, the…

Computer Vision and Pattern Recognition · Computer Science 2021-11-19 Prabhat KC , Rongping Zeng , M. Mehdi Farhangi , Kyle J. Myers

Purpose/Objectives: To develop and assess a strategy of using deep learning (DL) to generate virtual monochromatic CT (VMCT) images from a single-energy CT (SECT) scan. Materials/Methods: The proposed data-driven VMCT imaging consists of…

Medical Physics · Physics 2020-05-21 Wei Zhao , Tianling Lyu , Yang Chen , Lei Xing

Background: Cardiac resynchronization therapy (CRT) has emerged as an effective treatment for heart failure patients with electrical dyssynchrony. However, accurately predicting which patients will respond to CRT remains a challenge. This…

Signal Processing · Electrical Eng. & Systems 2023-06-05 Zhuo He , Hongjin Si , Xinwei Zhang , Qing-Hui Chen , Jiangang Zou , Weihua Zhou

Deep learning based single image super resolution (SISR) algorithms has revolutionized the overall diagnosis framework by continually improving the architectural components and training strategies associated with convolutional neural…

Image and Video Processing · Electrical Eng. & Systems 2022-03-15 Fayaz Ali Dharejo , Muhammad Zawish , Farah Deeba Yuanchun Zhou , Kapal Dev , Sunder Ali Khowaja , Nawab Muhammad Faseeh Qureshi

Purpose: This study aims to develop and validate a method for synthesizing 3D nephrographic phase images in CT urography (CTU) examinations using a diffusion model integrated with a Swin Transformer-based deep learning approach. Materials…

Personalized computed tomography (CT) dosimetry has great potential in assessing patient-specific radiation exposure, supporting risk assessment, and optimizing clinical protocols. The aim of this study is to evaluate the potential of…

Medical Physics · Physics 2026-01-15 Marie-Luise Kuhlmann , Jörg Martin , Stefan Pojtinger

Compressed Sensing MRI (CS-MRI) has provided theoretical foundations upon which the time-consuming MRI acquisition process can be accelerated. However, it primarily relies on iterative numerical solvers which still hinders their adaptation…

Computer Vision and Pattern Recognition · Computer Science 2018-06-12 Tran Minh Quan , Thanh Nguyen-Duc , Won-Ki Jeong

Objective: Cone-beam computed tomography (CBCT) provides a low-dose imaging alternative to conventional CT, but suffers from noise, scatter, and artifacts that degrade image quality. Synthetic CT (sCT) aims to translate CBCT to high-quality…

Medical Physics · Physics 2025-09-23 Alzahra Altalib , Chunhui Li , Alessandro Perelli

Deep learning-based Generative Models have the potential to convert low-resolution CT images into high-resolution counterparts without long acquisition times and increased radiation exposure in thin-slice CT imaging. However, procuring…

Image and Video Processing · Electrical Eng. & Systems 2024-06-04 Zeyu Tang , Xiaodan Xing , Guang Yang

Attenuation correction is an essential requirement of positron emission tomography (PET) image reconstruction to allow for accurate quantification. However, attenuation correction is particularly challenging for PET-MRI as neither PET nor…

Purpose The purpose of this study was to develop and evaluate a deep neural network (DNN) capable of generating flat-panel detector (FPD) images from digitally reconstructed radiography (DRR) images in lung cancer treatment, with the aim of…

Computer Vision and Pattern Recognition · Computer Science 2025-03-04 Chisako Hayashi , Shinichiro Mori , Yasukuni Mori , Lim Taehyeung , Hiroki Suyari , Hitoshi Ishikawa

Due to the inter- and intra- variation of respiratory motion, it is highly desired to provide real-time volumetric images during the treatment delivery of lung stereotactic body radiation therapy (SBRT) for accurate and active motion…

The radiation dose in computed tomography (CT) examinations is harmful for patients but can be significantly reduced by intuitively decreasing the number of projection views. Reducing projection views usually leads to severe aliasing…

Image and Video Processing · Electrical Eng. & Systems 2022-11-28 Bing Guan , Cailian Yang , Liu Zhang , Shanzhou Niu , Minghui Zhang , Yuhao Wang , Weiwen Wu , Qiegen Liu