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Recent deep learning based single image super-resolution (SISR) methods mostly train their models in a clean data domain where the low-resolution (LR) and the high-resolution (HR) images come from noise-free settings (same domain) due to…

Image and Video Processing · Electrical Eng. & Systems 2020-09-09 Rao Muhammad Umer , Christian Micheloni

Computed tomography (CT) equivalent information is needed for attenuation correction in PET imaging and for dose planning in radiotherapy. Prior work has shown that Gaussian mixture models can be used to generate a substitute CT (s-CT)…

Applications · Statistics 2016-09-29 Anders Hildeman , David Bolin , Jonas Wallin , Adam Johansson , Tufve Nyholm , Thomas Asklund , Jun Yu

Magnetic resonance (MR) and computer tomography (CT) images are two typical types of medical images that provide mutually-complementary information for accurate clinical diagnosis and treatment. However, obtaining both images may be limited…

Image and Video Processing · Electrical Eng. & Systems 2023-06-02 Jiayuan Wang , Q. M. Jonathan Wu , Farhad Pourpanah

Synthetic CT image generation from MRI scan is necessary to create radiotherapy plans without the need of co-registered MRI and CT scans. The chosen baseline adversarial model with cycle consistency permits unpaired image-to-image…

Image and Video Processing · Electrical Eng. & Systems 2023-08-16 Denis Prokopenko , Joël Valentin Stadelmann , Heinrich Schulz , Steffen Renisch , Dmitry V. Dylov

Accurate MR-to-CT synthesis is a requirement for MR-only workflows in radiotherapy (RT) treatment planning. In recent years, deep learning-based approaches have shown impressive results in this field. However, to prevent downstream errors…

Image and Video Processing · Electrical Eng. & Systems 2019-11-13 Louis D. van Harten , Jelmer M. Wolterink , Joost J. C. Verhoeff , Ivana Išgum

Purpose: Deformable image registration (DIR) is critical in adaptive radiation therapy (ART) to account for anatomical changes. Conventional intensity-based DIR methods often fail when image intensities differ. This study evaluates a hybrid…

Medical Physics · Physics 2024-11-27 Keyur D. Shah , James A. Shackleford , Nagarajan Kandasamy , Gregory C. Sharp

Positron Emission Tomography (PET) imaging requires accurate attenuation correction (AC) to account for photon loss due to tissue density variations. In PET/MR systems, computed tomography (CT), which offers a straightforward estimation of…

Image and Video Processing · Electrical Eng. & Systems 2025-04-11 Weijie Chen , James Wang , Alan McMillan

Positron emission tomography (PET) is a critical tool for diagnosing tumors and neurological disorders but poses radiation risks to patients, particularly to sensitive populations. While reducing injected radiation dose mitigates this risk,…

Image and Video Processing · Electrical Eng. & Systems 2026-04-01 Yucun Hou , Fenglin Zhan , Xin Cheng , Chenxi Li , Ziquan Yuan , Runze Liao , Haihao Wang , Jianlang Hua , Jing Wu , Jianyong Jiang

MR imaging will play a very important role in radiotherapy treatment planning for segmentation of tumor volumes and organs. However, the use of MR-based radiotherapy is limited because of the high cost and the increased use of metal…

Computer Vision and Pattern Recognition · Computer Science 2018-09-05 Cheng-Bin Jin , Hakil Kim , Wonmo Jung , Seongsu Joo , Ensik Park , Ahn Young Saem , In Ho Han , Jae Il Lee , Xuenan Cui

The purpose of this study is to develop a deep learning based method that can automatically generate segmentations on cone-beam CT (CBCT) for head and neck online adaptive radiation therapy (ART), where expert-drawn contours in planning CT…

Medical Physics · Physics 2021-02-02 Xiao Liang , Howard Morgan , Dan Nguyen , Steve Jiang

Computed tomography (CT) is a popular medical imaging modality in clinical applications. At the same time, the x-ray radiation dose associated with CT scans raises public concerns due to its potential risks to the patients. Over the past…

Computer Vision and Pattern Recognition · Computer Science 2018-08-13 Chenyu You , Qingsong Yang , Hongming Shan , Lars Gjesteby , Guang Li , Shenghong Ju , Zhuiyang Zhang , Zhen Zhao , Yi Zhang , Wenxiang Cong , Ge Wang

Generating synthetic CT (sCT) from MRI or CBCT plays a crucial role in enabling MRI-only and CBCT-based adaptive radiotherapy, improving treatment precision while reducing patient radiation exposure. To address this task, we adopt a fully…

Computer Vision and Pattern Recognition · Computer Science 2026-04-24 Arnela Hadzic , Simon Johannes Joham , Martin Urschler

Supervised deep-learning (SDL) techniques with paired training datasets have been widely studied for X-ray computed tomography (CT) image reconstruction. However, due to the difficulties of obtaining paired training datasets in clinical…

Image and Video Processing · Electrical Eng. & Systems 2025-01-06 Gaofeng Chen , Yaoduo Zhang , Li Huang , Pengfei Wang , Wenyu Zhang , Dong Zeng , Jianhua Ma , Ji He

Providing more precise tissue attenuation information, synthetic computed tomography (sCT) generated from magnetic resonance imaging (MRI) contributes to improved radiation therapy treatment planning. In our study, we employ the advanced…

Image and Video Processing · Electrical Eng. & Systems 2024-09-11 Fuxin Fan , Jingna Qiu , Yixing Huang , Andreas Maier

Purpose: To develop and evaluate a transformer-based deep learning model for the synthesis of nephrographic phase images in CT urography (CTU) examinations from the unenhanced and urographic phases. Materials and Methods: This retrospective…

Deformable Image Registration (DIR) of MR and CT images is one of the most challenging registration task, due to the inherent structural differences of the modalities and the missing dense ground truth. Recently cycle Generative Adversarial…

Computer Vision and Pattern Recognition · Computer Science 2018-07-20 Christine Tanner , Firat Ozdemir , Romy Profanter , Valeriy Vishnevsky , Ender Konukoglu , Orcun Goksel

Purpose: To investigate whether synthetically generated fractal data can be used to train deep learning (DL) models for dynamic MRI reconstruction, thereby avoiding the privacy, licensing, and availability limitations associated with…

Computer Vision and Pattern Recognition · Computer Science 2026-04-01 Anirudh Raman , Olivier Jaubert , Mark Wrobel , Tina Yao , Ruaraidh Campbell , Rebecca Baker , Ruta Virsinskaite , Daniel Knight , Michael Quail , Jennifer Steeden , Vivek Muthurangu

CT is commonly used in orthopedic procedures. MRI is used along with CT to identify muscle structures and diagnose osteonecrosis due to its superior soft tissue contrast. However, MRI has poor contrast for bone structures. Clearly, it would…

Computer Vision and Pattern Recognition · Computer Science 2018-08-01 Yuta Hiasa , Yoshito Otake , Masaki Takao , Takumi Matsuoka , Kazuma Takashima , Jerry L. Prince , Nobuhiko Sugano , Yoshinobu Sato

Contrast-enhanced computed tomography angiograms (CTAs) are widely used in cardiovascular imaging to obtain a non-invasive view of arterial structures. However, contrast agents are associated with complications at the injection site as well…

Image and Video Processing · Electrical Eng. & Systems 2020-03-04 Anirudh Chandrashekar , Ashok Handa , Natesh Shivakumar , Pierfrancesco Lapolla , Vicente Grau , Regent Lee

Image reconstruction from insufficient data is common in computed tomography (CT), e.g., image reconstruction from truncated data, limited-angle data and sparse-view data. Deep learning has achieved impressive results in this field.…

Image and Video Processing · Electrical Eng. & Systems 2020-05-21 Yixing Huang , Alexander Preuhs , Michael Manhart , Guenter Lauritsch , Andreas Maier