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Related papers: Weighted Q-learning for optimal dynamic treatment …

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When treatment effects are naturally expressed as ratios -- as in medicine, pricing, and marketing -- the ratio-based CATE $\tau(x) = E[Y|W=1,X=x] / E[Y|W=0,X=x]$ is the appropriate estimand. Yet existing estimators either impose a…

Machine Learning · Statistics 2026-05-27 Michael Fuchs , Dominik Kreiss

Though deep learning has achieved advanced performance recently, it remains a challenging task in the field of medical imaging, as obtaining reliable labeled training data is time-consuming and expensive. In this paper, we propose a…

Computer Vision and Pattern Recognition · Computer Science 2020-10-20 Yixin Wang , Yao Zhang , Jiang Tian , Cheng Zhong , Zhongchao Shi , Yang Zhang , Zhiqiang He

This paper develops a novel control-theoretic framework to analyze the non-asymptotic convergence of Q-learning. We show that the dynamics of asynchronous Q-learning with a constant step-size can be naturally formulated as a discrete-time…

Optimization and Control · Mathematics 2024-08-23 Donghwan Lee , Jianghai Hu , Niao He

Q-learning is known as one of the fundamental reinforcement learning (RL) algorithms. Its convergence has been the focus of extensive research over the past several decades. Recently, a new finitetime error bound and analysis for Q-learning…

Systems and Control · Electrical Eng. & Systems 2024-01-17 Donghwna Lee

Optimal dynamic treatment regimes (DTRs), as a key part of precision medicine, have progressively gained more attention recently. To inform clinical decision making, interpretable and parsimonious models for contrast functions are…

Methodology · Statistics 2025-12-08 Chunyu Wang , Brian Tom

Objective: The proper handling of missing values is critical to delivering reliable estimates and decisions, especially in high-stakes fields such as clinical research. The increasing diversity and complexity of data have led many…

Deep Reinforcement Learning has shown excellent performance in generating efficient solutions for complex tasks. However, its efficacy is often limited by static training modes and heavy reliance on vast data from stable environments. To…

Machine Learning · Computer Science 2024-11-06 Xinhao Zhang , Jinghan Zhang , Wujun Si , Kunpeng Liu

Deep neural networks (DNNs) have become powerful tools for modeling complex data structures through sequentially integrating simple functions in each hidden layer. In survival analysis, recent advances of DNNs primarily focus on enhancing…

Machine Learning · Statistics 2025-03-26 Changhui Yuan , Shishun Zhao , Shuwei Li , Xinyuan Song , Zhao Chen

The optimistic nature of the Q-learning target leads to an overestimation bias, which is an inherent problem associated with standard $Q-$learning. Such a bias fails to account for the possibility of low returns, particularly in risky…

Machine Learning · Computer Science 2021-11-05 Thommen George Karimpanal , Hung Le , Majid Abdolshah , Santu Rana , Sunil Gupta , Truyen Tran , Svetha Venkatesh

Objective: Estimation of the global optima of multiple model parameters is valuable in imaging to form a reliable diagnostic image. Given non convexity of the objective function, it is challenging to avoid from different local minima.…

Machine Learning · Computer Science 2022-04-06 Hongmei Zhang , Kai Wang , Yan Zhou , Shadab Momin , Xiaofeng Yang , Mostafa Fatemi , Michael F. Insana

``Distribution shift'' is the main obstacle to the success of offline reinforcement learning. A learning policy may take actions beyond the behavior policy's knowledge, referred to as Out-of-Distribution (OOD) actions. The Q-values for…

Machine Learning · Computer Science 2025-01-14 Jing Zhang , Linjiajie Fang , Kexin Shi , Wenjia Wang , Bing-Yi Jing

Accurate models of clinical actions and their impacts on disease progression are critical for estimating personalized optimal dynamic treatment regimes (DTRs) in medical/health research, especially in managing chronic conditions.…

Methodology · Statistics 2021-02-19 William Hua , Hongyuan Mei , Sarah Zohar , Magali Giral , Yanxun Xu

A novel class of advanced algorithms, termed Goal-Conditioned Weighted Supervised Learning (GCWSL), has recently emerged to tackle the challenges posed by sparse rewards in goal-conditioned reinforcement learning (RL). GCWSL consistently…

Machine Learning · Computer Science 2025-06-10 Xing Lei , Xuetao Zhang , Zifeng Zhuang , Donglin Wang

Recent research has shown that although Reinforcement Learning (RL) can benefit from expert demonstration, it usually takes considerable efforts to obtain enough demonstration. The efforts prevent training decent RL agents with expert…

Machine Learning · Computer Science 2021-07-09 Si-An Chen , Voot Tangkaratt , Hsuan-Tien Lin , Masashi Sugiyama

Double Q-learning is a classical method for reducing overestimation bias, which is caused by taking maximum estimated values in the Bellman operation. Its variants in the deep Q-learning paradigm have shown great promise in producing…

Machine Learning · Computer Science 2022-01-17 Zhizhou Ren , Guangxiang Zhu , Hao Hu , Beining Han , Jianglun Chen , Chongjie Zhang

Electronic health records (EHR) are characterized as non-stationary, heterogeneous, noisy, and sparse data; therefore, it is challenging to learn the regularities or patterns inherent within them. In particular, sparseness caused mostly by…

Machine Learning · Computer Science 2020-03-03 Eunji Jun , Ahmad Wisnu Mulyadi , Jaehun Choi , Heung-Il Suk

The missing data issue is ubiquitous in health studies. Variable selection in the presence of both missing covariates and outcomes is an important statistical research topic but has been less studied. Existing literature focuses on…

Methodology · Statistics 2021-07-09 Liangyuan Hu , Jung-Yi Joyce Lin , Jiayi Ji

Value decomposition (VD) methods have achieved remarkable success in cooperative multi-agent reinforcement learning (MARL). However, their reliance on the max operator for temporal-difference (TD) target calculation leads to systematic…

Multiagent Systems · Computer Science 2026-02-27 Yuanjun Li , Bin Zhang , Hao Chen , Zhouyang Jiang , Dapeng Li , Zhiwei Xu

Inverse reinforcement learning (IRL), which infers reward functions from demonstrations, is a valuable tool for modeling and understanding decision-making behavior. Many variants of IRL have been developed to capture complexities of human…

Machine Learning · Computer Science 2026-05-14 Leo Benac , Abhishek Sharma , Alihan Huyuk , Finale Doshi-Velez

Reinforcement learning (RL) has garnered increasing recognition for its potential to optimise dynamic treatment regimes (DTRs) in personalised medicine, particularly for drug dosage prescriptions and medication recommendations. However, a…

Machine Learning · Computer Science 2024-05-30 Zhiyao Luo , Mingcheng Zhu , Fenglin Liu , Jiali Li , Yangchen Pan , Jiandong Zhou , Tingting Zhu
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