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Capturing depth and reflectivity images at low light levels from active illumination of a scene has wide-ranging applications. Conventionally, even with single-photon detectors, hundreds of photon detections are needed at each pixel to…
Number-resolving single photon detectors are essential for the implementation of numerous innovative quantum information schemes. While several number-discriminating techniques have been previously presented, the Silicon Photo-Multiplier…
Verification of patient specific proton stopping powers obtained in the patient treatment position can be used to reduce the distal margins needed in particle beam planning. Proton radiography can be used as a pre-treatment instrument to…
Positron range (PR) limits spatial resolution and quantitative accuracy in PET imaging, particularly for high-energy positron-emitting radionuclides like 68Ga. We propose a deep learning method using 3D residual encoder-decoder…
In recent decades, developments in detectors for X-ray imaging have improved dose efficiency. This has been accomplished with for example, structured scintillators such as columnar CsI, or with direct detectors where the X rays are…
Clot formation is a common complication in extracorporeal circuits. In this paper we describe a novel method for clot formation analysis using image processing. We assembled a closed extracorporeal circuit and circulated blood at varying…
This study presents a practical and dose-efficient strategy for resolution enhancement in planar radiography, based on mechanically supersampled acquisition with high-Z photon-counting detectors (PCDs). Unlike prior event-based or cluster…
Cone-beam computed tomography (CBCT) has been widely used in medical imaging and industrial nondestructive testing, but the presence of scattered radiation will cause significant reduction of image quality. In this article, a robust scatter…
Colonoscopy screening effectively identifies and removes polyps before they progress to colorectal cancer (CRC), but current follow-up guidelines rely primarily on histopathological features, overlooking other important CRC risk factors.…
A robust post processing technique is mandatory to analyse the coronagraphic high contrast imaging data. Angular Differential Imaging (ADI) and Principal Component Analysis (PCA) are the most used approaches to suppress the quasi-static…
CT protocol design and quality control would benefit from automated tools to estimate the quality of generated CT images. These tools could be used to identify erroneous CT acquisitions or refine protocols to achieve certain signal to noise…
Photon counting is a cornerstone of quantum optics. Here, we demonstrate precisely counting from 0 to over 9000 photons, beating the Poisson noise limit by at least $4.1~\mathrm{dB}$ across this range. We achieve sub-single-photon precision…
We propose a new modeling approach for scatter estimation and descattering in polyenergetic X-ray computed tomography (CT) based on fitting models to local neighborhoods of a training set. X-ray CT is widely used in medical and industrial…
Coronary artery calcium (CAC) scoring plays a crucial role in the early detection and risk stratification of coronary artery disease (CAD). In this study, we focus on non-contrast coronary computed tomography angiography (CCTA) scans, which…
Coronary artery disease (CAD) is the dominant cause of death and hospitalization across the globe. Atherosclerosis, an inflammatory condition that gradually narrows arteries and has potentially fatal effects, is the most frequent cause of…
In a standard computed tomography (CT) image, pixels having the same Hounsfield Units (HU) can correspond to different materials and it is therefore challenging to differentiate and quantify materials. Dual-energy CT (DECT) is desirable to…
Radiotherapy is one of the main methods in the successful treatment of cancer. The tumor is irradiated with photons or charged particles (e.g. protons), and in the case of massive charged particles, the treatment results in less unnecessary…
We have recently introduced the idea of making use of three-photon positron annihilations in positron emission tomography. In this paper the basic characteristics of the three-gamma imaging in PET are studied by means of Monte Carlo…
X-Ray Phase-Contrast Imaging (PCI) yields absorption, differential phase, and dark-field images. Computed Tomography (CT) of grating-based PCI can in principle provide high-resolution soft-tissue contrast. Recently, grating-based PCI took…
Computed tomography (CT) is a widely used non-invasive medical imaging technique for disease diagnosis. The diagnostic accuracy is often affected by image resolution, which can be insufficient in practice. For medical CT images, the…