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Due to its wide field of view, cone-beam computed tomography (CBCT) is plagued by large amounts of scatter, where attenuated photons hit the detector, and corrupt the linear models used for reconstruction. Given that one can generate a good…
In computed tomography (CT) reconstruction, scattering causes server quality degradation of the reconstructed CT images by introducing streaks and cupping artifacts which reduce the detectability of low contrast objects. Monte Carlo (MC)…
Compared with the start-of-art energy integration detectors (EIDs), photon-counting detectors (PCDs) with energy discrimination capabilities have demonstrated great potentials in various applications of medical x-ray radiography and…
In current clinical practice, noisy and artifact-ridden weekly cone-beam computed tomography (CBCT) images are only used for patient setup during radiotherapy. Treatment planning is done once at the beginning of the treatment using…
Background: Ultrasound imaging plays a pivotal role in diagnosing carotid atherosclerosis, a significant precursor to cardiovascular and cerebrovascular diseases and events. This non-invasive modality provides real-time, high-resolution…
High-quality ultrafast ultrasound imaging is based on coherent compounding from multiple transmissions of plane waves (PW) or diverging waves (DW). However, compounding results in reduced frame rate, as well as destructive interferences…
X-ray computed tomography (CT) has an indispensable role in constructing 3D images of objects made from light materials. However, limited by absorption coefficients, X-rays cannot deeply penetrate materials such as copper and lead. Here we…
We are exploring low-dose proton radiography and computed tomography (pCT) as techniques to improve the accuracy of proton treatment planning and to provide artifact-free images for verification and adaptive therapy at the time of…
Coronary artery calcification (CAC) is a strong and independent predictor of cardiovascular disease (CVD). However, manual assessment of CAC often requires radiological expertise, time, and invasive imaging techniques. The purpose of this…
Computed tomography (CT) is increasingly being used for cancer screening, such as early detection of lung cancer. However, CT studies have varying pixel spacing due to differences in acquisition parameters. Thick slice CTs have lower…
A detailed and accurate characterisation of silicon photomultiplier detectors is required for a better understanding of the signal and noise in many applications. The collected information is a valuable feedback to the manufacturers in…
Photon-limited imaging arises when the number of photons collected by a sensor array is small relative to the number of detector elements. Photon limitations are an important concern for many applications such as spectral imaging, night…
X-ray computed tomography (CT) based on photon counting detectors (PCD) extends standard CT by counting detected photons in multiple energy bins. PCD data can be used to increase the contrast-to-noise ratio (CNR), increase spatial…
Targeted diagnosis and treatment plans for patients with coronary artery disease vary according to atherosclerotic plaque component. Coronary CT angiography (CCTA) is widely used for artery imaging and determining the stenosis degree.…
Radiation therapy with protons as of today utilizes information from x-ray CT in order to estimate the proton stopping power of the traversed tissue in a patient. The conversion from x-ray attenuation to proton stopping power in tissue…
The increasingly demand for machining accuracy and product quality excites a great interest in high-resolution non-destructive testing (NDT) methods, but spatial resolution of conventional high-energy computed tomography (CT) is limited to…
Patients undergoing a mechanical thrombectomy procedure usually have a multi-detector CT (MDCT) scan before and after the intervention. The image quality of the flat panel detector CT (FDCT) present in the intervention room is generally…
It has previously been shown that 2D spectral mammography can be used to discriminate between (likely benign) cystic and (potentially malignant) solid lesions in order to reduce unnecessary recalls in mammography. One limitation of the…
Cardiac computed tomography (CT) has emerged as a major imaging modality for the diagnosis and monitoring of cardiovascular diseases. High temporal resolution is essential to ensure diagnostic accuracy. Limited-angle data acquisition can…
{The study of frequency components derived from Discrete Cosine Transform (DCT) has been widely used in image analysis. In recent years it has been observed that significant information can be extrapolated from them about the lifecycle of…