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In clinical practice, tri-modal medical image fusion, compared to the existing dual-modal technique, can provide a more comprehensive view of the lesions, aiding physicians in evaluating the disease's shape, location, and biological…
Diffusion models achieved great success in image synthesis, but still face challenges in high-resolution generation. Through the lens of discrete cosine transformation, we find the main reason is that \emph{the same noise level on a higher…
Multiple Instance Learning (MIL), a powerful strategy for weakly supervised learning, is able to perform various prediction tasks on gigapixel Whole Slide Images (WSIs). However, the tens of thousands of patches in WSIs usually incur a vast…
Integrating deep learning with clinical expertise holds great potential for addressing healthcare challenges and empowering medical professionals with improved diagnostic tools. However, the need for annotated medical images is often an…
The Latent Diffusion Model (LDM) has demonstrated strong capabilities in high-resolution image generation and has been widely employed for Pose-Guided Person Image Synthesis (PGPIS), yielding promising results. However, the compression…
Foundation models have revolutionized computational pathology by achieving remarkable success in high-level diagnostic tasks, yet the critical challenge of low-level image enhancement remains largely unaddressed. Real-world pathology images…
Diffusion models have recently gained recognition for generating diverse and high-quality content, especially in image synthesis. These models excel not only in creating fixed-size images but also in producing panoramic images. However,…
Diffusion models have shown great results in image generation and in image editing. However, current approaches are limited to low resolutions due to the computational cost of training diffusion models for high-resolution generation. We…
Diabetic Foot Ulcer (DFU) is a serious skin wound requiring specialized care. However, real DFU datasets are limited, hindering clinical training and research activities. In recent years, generative adversarial networks and diffusion models…
In recent years, computational pathology has seen tremendous progress driven by deep learning methods in segmentation and classification tasks aiding prognostic and diagnostic settings. Nuclei segmentation, for instance, is an important…
By decomposing the image formation process into a sequential application of denoising autoencoders, diffusion models (DMs) achieve state-of-the-art synthesis results on image data and beyond. Additionally, their formulation allows for a…
Visual microscopic study of diseased tissue by pathologists has been the cornerstone for cancer diagnosis and prognostication for more than a century. Recently, deep learning methods have made significant advances in the analysis and…
Continuous Conditional Diffusion Model (CCDM) is a diffusion-based framework designed to generate high-quality images conditioned on continuous regression labels. Although CCDM has demonstrated clear advantages over prior approaches across…
Low-field to high-field MRI synthesis has emerged as a cost-effective strategy to enhance image quality under hardware and acquisition constraints, particularly in scenarios where access to high-field scanners is limited or impractical.…
We introduce Home-made Diffusion Model (HDM), an efficient yet powerful text-to-image diffusion model optimized for training (and inferring) on consumer-grade hardware. HDM achieves competitive 1024x1024 generation quality while maintaining…
Lung cancer has been one of the leading causes of cancer-related deaths worldwide for years. With the emergence of deep learning, computer-assisted diagnosis (CAD) models based on learning algorithms can accelerate the nodule screening…
Access to high-quality datasets in the medical industry limits machine learning model performance. To address this issue, we propose a Denoising Diffusion Probabilistic Model (DDPM) combined with a UNet architecture for X-ray image…
In this paper, we present Diffusion-4K, a novel framework for direct ultra-high-resolution image synthesis using text-to-image diffusion models. The core advancements include: (1) Aesthetic-4K Benchmark: addressing the absence of a publicly…
We present an unsupervised single image bidirectional Magnetic Resonance Image (MRI) synthesizer that synthesizes an Ultra-Low Field (ULF) like image from a High-Field (HF) magnitude image and vice-versa. Unlike existing MRI synthesis…
Paucity of medical data severely limits the generalizability of diagnostic ML models, as the full spectrum of disease variability can not be represented by a small clinical dataset. To address this, diffusion models (DMs) have been…