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Causal discovery is a fundamental problem with applications spanning various areas in science and engineering. It is well understood that solely using observational data, one can only orient the causal graph up to its Markov equivalence…

Machine Learning · Computer Science 2024-10-29 Zihan Zhou , Muhammad Qasim Elahi , Murat Kocaoglu

We give methods for Bayesian inference of directed acyclic graphs, DAGs, and the induced causal effects from passively observed complete data. Our methods build on a recent Markov chain Monte Carlo scheme for learning Bayesian networks,…

Machine Learning · Computer Science 2020-11-19 Jussi Viinikka , Antti Hyttinen , Johan Pensar , Mikko Koivisto

We consider the problem of estimating causal DAG models from a mix of observational and interventional data, when the intervention targets are partially or completely unknown. This problem is highly relevant for example in genomics, since…

Methodology · Statistics 2020-06-23 Chandler Squires , Yuhao Wang , Caroline Uhler

We consider the problem of learning causal DAGs in the setting where both observational and interventional data is available. This setting is common in biology, where gene regulatory networks can be intervened on using chemical reagents or…

Methodology · Statistics 2019-02-08 Karren D. Yang , Abigail Katcoff , Caroline Uhler

In many applications we have both observational and (randomized) interventional data. We propose a Gaussian likelihood framework for joint modeling of such different data-types, based on global parameters consisting of a directed acyclic…

Statistics Theory · Mathematics 2014-06-03 Alain Hauser , Peter Bühlmann

Graphical models based on Directed Acyclic Graphs (DAGs) are widely used to answer causal questions across a variety of scientific and social disciplines. However, observational data alone cannot distinguish in general between DAGs…

Methodology · Statistics 2022-06-03 Federico Castelletti , Guido Consonni

We consider a binary response which is potentially affected by a set of continuous variables. Of special interest is the causal effect on the response due to an intervention on a specific variable. The latter can be meaningfully determined…

Methodology · Statistics 2020-09-11 Federico Castelletti , Guido Consonni

Bayesian causal discovery aims to infer the posterior distribution over causal models from observed data, quantifying epistemic uncertainty and benefiting downstream tasks. However, computational challenges arise due to joint inference over…

Machine Learning · Computer Science 2023-12-11 Yashas Annadani , Nick Pawlowski , Joel Jennings , Stefan Bauer , Cheng Zhang , Wenbo Gong

Inferring the causal relationships among a set of variables in the form of a directed acyclic graph (DAG) is an important but notoriously challenging problem. Recently, advancements in high-throughput genomic perturbation screens have…

Machine Learning · Computer Science 2025-10-03 Seong Woo Han , Daniel Duy Vo , Brielin C. Brown

The investigation of directed acyclic graphs (DAGs) encoding the same Markov property, that is the same conditional independence relations of multivariate observational distributions, has a long tradition; many algorithms exist for model…

Methodology · Statistics 2012-09-27 Alain Hauser , Peter Bühlmann

Directed Acyclic Graphs (DAGs) provide a powerful framework to model causal relationships among variables in multivariate settings; in addition, through the do-calculus theory, they allow for the identification and estimation of causal…

Machine Learning · Statistics 2022-01-31 Federico Castelletti , Alessandro Mascaro

We consider a a collection of categorical random variables. Of special interest is the causal effect on an outcome variable following an intervention on another variable. Conditionally on a Directed Acyclic Graph (DAG), we assume that the…

Methodology · Statistics 2023-06-29 Federico Castelletti , Guido Consonni , Marco Luigi Della Vedova

Describing the causal relations governing a system is a fundamental task in many scientific fields, ideally addressed by experimental studies. However, obtaining data under intervention scenarios may not always be feasible, while…

Methodology · Statistics 2022-05-06 Jack Kuipers , Giusi Moffa

Causal interactions among a group of variables are often modeled by a single causal graph. In some domains, however, these interactions are best described by multiple co-existing causal graphs, e.g., in dynamical systems or genomics. This…

Machine Learning · Computer Science 2024-12-04 Burak Varıcı , Dmitriy Katz-Rogozhnikov , Dennis Wei , Prasanna Sattigeri , Ali Tajer

The increasing availability of interventional data offers new opportunities for causal discovery, with gene perturbation studies providing a prominent example. Such data are typically count-valued and subject to substantial measurement…

Methodology · Statistics 2026-03-30 Yijiao Zhang , Hongzhe Li

It is known that from purely observational data, a causal DAG is identifiable only up to its Markov equivalence class, and for many ground truth DAGs, the direction of a large portion of the edges will be remained unidentified. The golden…

Machine Learning · Computer Science 2019-10-15 AmirEmad Ghassami , Saber Salehkaleybar , Negar Kiyavash

Directed acyclic graphical (DAG) models are a powerful tool for representing causal relationships among jointly distributed random variables, especially concerning data from across different experimental settings. However, it is not always…

Machine Learning · Statistics 2026-04-03 Francisco Madaleno , Pratik Misra , Alex Markham

We consider the problem of learning the underlying causal structure among a set of variables, which are assumed to follow a Bayesian network or, more specifically, a linear recursive structural equation model (SEM) with the associated…

Statistics Theory · Mathematics 2025-08-05 Anamitra Chaudhuri , Anirban Bhattacharya , Yang Ni

Quantifying causal effects of exposures on outcomes, such as a treatment and a disease respectively, is a crucial issue in medical science for the administration of effective therapies. Importantly, any related causal analysis should…

Methodology · Statistics 2024-09-04 Federico Castelletti , Laura Ferrini

Bayesian causal discovery offers the power to quantify epistemic uncertainties among a broad range of structurally diverse causal theories potentially explaining the data, represented in forms of directed acyclic graphs (DAGs). However,…

Machine Learning · Computer Science 2024-08-30 Nu Hoang , Bao Duong , Thin Nguyen
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