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Counting cells in fluorescent microscopy is a tedious, time-consuming task that researchers have to accomplish to assess the effects of different experimental conditions on biological structures of interest. Although such objects are…

Computer Vision and Pattern Recognition · Computer Science 2021-03-02 R. Morelli , L. Clissa , M. Dalla , M. Luppi , L. Rinaldi , A. Zoccoli

The current work reports an efficient deep neural network (DNN) accelerator where synaptic weight elements are controlled by ferroelectric domain dynamics. An integrated device-to-algorithm framework for benchmarking novel synaptic devices…

Emerging Technologies · Computer Science 2022-10-14 Sayani Majumdar

Tissue stiffness is related to soft tissue pathologies and can be assessed through palpation or via clinical imaging systems, e.g., ultrasound or magnetic resonance imaging. Typically, the image based approaches are not suitable during…

Signal Processing · Electrical Eng. & Systems 2025-09-04 Maximilian Neidhardt , Sarah Latus , Tim Eixmann , Gereon Hüttmann , Alexander Schlaefer

Activity detection is an important task in the next generation grant-free multiple access. While there are a number of existing algorithms designed for this purpose, they mostly require precise information about the network, such as…

Machine Learning · Computer Science 2024-02-05 Hao Zhang , Qingfeng Lin , Yang Li , Lei Cheng , Yik-Chung Wu

A fundamental challenge in calcium imaging has been to infer the timing of action potentials from the measured noisy calcium fluorescence traces. We systematically evaluate a range of spike inference algorithms on a large benchmark dataset…

Synaptic plasticity, the dynamic tuning of signal transmission strength between neurons, serves as a fundamental basis for memory and learning in biological organisms. This adaptive nature of synapses is considered one of the key features…

Mesoscale and Nanoscale Physics · Physics 2024-11-11 Yechan Noh , Alex Smolyanitsky

Brain function results from communication between neurons connected by complex synaptic networks. Synapses are themselves highly complex and diverse signaling machines, containing protein products of hundreds of different genes, some in…

Computer Vision and Pattern Recognition · Computer Science 2017-07-05 Anish K. Simhal , Cecilia Aguerrebere , Forrest Collman , Joshua T. Vogelstein , Kristina D. Micheva , Richard J. Weinberg , Stephen J. Smith , Guillermo Sapiro

This paper offers a new authentication algorithm based on image matching of nano-resolution visual identifiers with tree-shaped patterns. The algorithm includes image-to-tree conversion by greedy extraction of the fractal pattern skeleton…

Computer Vision and Pattern Recognition · Computer Science 2022-11-16 Hao Wang , Xiwen Chen , Abolfazl Razi , Rahul Amin

Decoding behavior, such as movement, from multiscale brain networks remains a central objective in neuroscience. Over the past decades, artificial intelligence and machine learning have played an increasingly significant role in elucidating…

Neurons and Cognition · Quantitative Biology 2025-04-24 Ghazal Mirzaee , Jonathan Chang , Shahrzad Latifi

Rapid advancements in deep learning over the past decade have fueled an insatiable demand for efficient and scalable hardware. Photonics offers a promising solution by leveraging the unique properties of light. However, conventional neural…

Thanks to novel, powerful brain activity recording techniques, we can create data-driven models from thousands of recording channels and large portions of the cortex, which can improve our understanding of brain-states neuromodulation and…

Deep neural networks (DNNs) trained on visual tasks develop feature representations that resemble those in the human visual system. Although DNN-based encoding models can accurately predict brain responses to visual stimuli, they offer…

Computer Vision and Pattern Recognition · Computer Science 2025-06-06 Matthew W. Shinkle , Mark D. Lescroart

Spatiotemporal information is at the core of diverse sensory processing and computational tasks. Feed-forward spiking neural networks can be used to solve these tasks while offering potential benefits in terms of energy efficiency by…

Machine Learning · Computer Science 2026-03-11 Jann Krausse , Zhe Su , Kyrus Mama , Maryada , Klaus Knobloch , Giacomo Indiveri , Jürgen Becker

In life sciences, fluorescent labeling techniques are used to study molecular structures and interactions of cells. However, this type of cell imaging has its own limitations, one of which is that the process of staining the cells could be…

Image and Video Processing · Electrical Eng. & Systems 2020-05-07 Eunjae Kim

Neuromorphic Computing (NC), which emulates neural activities of the human brain, is considered for low-power implementation of artificial intelligence. Towards realizing NC, fabrication, and investigations of hardware elements such as…

Materials Science · Physics 2021-09-21 P. Monalisha , P. S. Anil Kumar , X. Renshaw Wang , S. N. Piramanayagam

In the brain, fine-scale correlations combine to produce macroscopic patterns of activity. However, as experiments record from larger and larger populations, we approach a fundamental bottleneck: the number of correlations one would like to…

Biological Physics · Physics 2024-02-02 Christopher W. Lynn , Qiwei Yu , Rich Pang , Stephanie E. Palmer , William Bialek

The Dendritic Cell Algorithm is an immune-inspired algorithm orig- inally based on the function of natural dendritic cells. The original instantiation of the algorithm is a highly stochastic algorithm. While the performance of the algorithm…

Artificial Intelligence · Computer Science 2010-07-05 Julie Greensmith , Uwe Aickelin

Recognizing human activities in a sequence is a challenging area of research in ubiquitous computing. Most approaches use a fixed size sliding window over consecutive samples to extract features---either handcrafted or learned…

Computer Vision and Pattern Recognition · Computer Science 2017-02-22 Rui Yao , Guosheng Lin , Qinfeng Shi , Damith Ranasinghe

Developing automated and semi-automated solutions for reconstructing wiring diagrams of the brain from electron micrographs is important for advancing the field of connectomics. While the ultimate goal is to generate a graph of neuron…

Computer Vision and Pattern Recognition · Computer Science 2016-08-09 William Gray Roncal , Colin Lea , Akira Baruah , Gregory D. Hager

Many real-world mission-critical applications require continual online learning from noisy data and real-time decision making with a defined confidence level. Probabilistic models and stochastic neural networks can explicitly handle…

Disordered Systems and Neural Networks · Physics 2022-06-01 Sourav Dutta , Georgios Detorakis , Abhishek Khanna , Benjamin Grisafe , Emre Neftci , Suman Datta