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With the increasing breaches and security threats that endanger health data, ensuring patients' privacy is essential. To that end, the research community has proposed various privacy-preserving approaches based on cryptography, hashing, or…

Cryptography and Security · Computer Science 2023-11-10 Sunanda Bose , Dusica Marijan

Since the advent of next-generation sequencing in the early 2000s, the volume of bioinformatics software tools and databases has exploded and continues to grow rapidly. Documenting this evolution on a global and time-dependent scale is a…

Scientific software is essential to scientific innovation and in many ways it is distinct from other types of software. Abandoned (or unmaintained), buggy, and hard to use software, a perception often associated with scientific software can…

Software Engineering · Computer Science 2025-06-23 Addi Malviya Thakur , Reed Milewicz , Mahmoud Jahanshahi , Lavínia Paganini , Bogdan Vasilescu , Audris Mockus

Advanced bioimaging technologies have enabled the large-scale acquisition of multidimensional data, yet effective metadata management and interoperability remain significant challenges. To address these issues, we propose a new…

Digital Libraries · Computer Science 2025-08-05 Yuki Yamagata , Koji Kyoda , Hiroya Itoga , Emi Fujisawa , Shuichi Onami

Life cycle assessment (LCA) plays a critical role in assessing the environmental impacts of a product, technology, or service throughout its entire life cycle. Nonetheless, many existing LCA tools and methods lack adequate metadata…

Databases · Computer Science 2024-05-17 Kourosh Malek , Max Dreger , Zirui Tang , Qingshi Tu

The computational demands for scientific applications are continuously increasing. The emergence of cloud computing has enabled on-demand resource allocation. However, relying solely on infrastructure as a service does not achieve the…

Distributed, Parallel, and Cluster Computing · Computer Science 2019-11-13 Marco Capuccini , Anders Larsson , Matteo Carone , Jon Ander Novella , Noureddin Sadawi , Jianliang Gao , Salman Toor , Ola Spjuth

Scientific discoveries are increasingly driven by analyzing large volumes of image data. Many new libraries and specialized database management systems (DBMSs) have emerged to support such tasks. It is unclear, however, how well these…

Imagine an online work environment where researchers have direct and immediate access to myriad data sources and tools and data management resources, useful throughout the research lifecycle. This is our vision for the next generation of…

Computers and Society · Computer Science 2015-06-19 Latanya Sweeney , Merce Crosas

Data reuse is fundamental for reducing the data integration effort required to build data supporting new applications, especially in data scarcity contexts. However, data reuse requires to deal with data heterogeneity, which is always…

Databases · Computer Science 2024-07-02 Simone Bocca , Amarsanaa Ganbold , Tsolmon Zundui

Big imaging data is becoming more prominent in brain sciences across spatiotemporal scales and phylogenies. We have developed a computational ecosystem that enables storage, visualization, and analysis of these data in the cloud, thusfar…

Error-controlled lossy compressors have been widely used in scientific applications to reduce the unprecedented size of scientific data while keeping data distortion within a user-specified threshold. While they significantly mitigate the…

Databases · Computer Science 2026-03-27 Xuan Wu , Sheng Di , Tripti Agarwal , Kai Zhao , Xin Liang , Franck Cappello

The availability of both structured and unstructured databases, such as electronic health data, social media data, patent data, and surveys that are often updated in real time, among others, has grown rapidly over the past decade. With this…

Databases · Computer Science 2023-07-26 Rebecca C. Steorts

The amount of data in the world is expanding rapidly. Every day, huge amounts of data are created by scientific experiments, companies, and end users' activities. These large data sets have been labeled as "Big Data", and their storage,…

Databases · Computer Science 2020-04-29 Mahdi Bohlouli , Frank Schulz , Lefteris Angelis , David Pahor , Ivona Brandic , David Atlan , Rosemary Tate

In this paper, we discuss the need for an integrated software stack that unites artificial intelligence (AI) and modeling and simulation (ModSim) tools to advance scientific discovery. The authors advocate for a unified AI/ModSim software…

Software Engineering · Computer Science 2024-11-15 Michael A. Heroux , Sameer Shende , Lois Curfman McInnes , Todd Gamblin , James M. Willenbring

Data science is a pillar of artificial intelligence (AI), which is transforming nearly every domain of human activity, from the social and physical sciences to engineering and medicine. While data-driven findings in AI offer unprecedented…

Machine Learning · Computer Science 2025-12-04 Zachary T. Rewolinski , Bin Yu

Data is crucial for machine learning (ML) applications, yet acquiring large datasets can be costly and time-consuming, especially in complex, resource-intensive fields like biopharmaceuticals. A key process in this industry is upstream…

Machine Learning · Computer Science 2025-06-23 Johnny Peng , Thanh Tung Khuat , Katarzyna Musial , Bogdan Gabrys

Scientific applications produce a huge amount of data, which imposes serious management and analysis challenges. In particular, limitations in current database management systems prevent their adoption in simulation applications, in which…

Databases · Computer Science 2019-03-18 Hermano Lustosa , Fabio Porto

Soon most information will be available at your fingertips, anytime, anywhere. Rapid advances in storage, communications, and processing allow us move all information into Cyberspace. Software to define, search, and visualize online…

Databases · Computer Science 2007-05-23 Jim Gray

The evolution of the Internet and computer applications have generated colossal amount of data. They are referred to as Big Data and they consist of huge volume, high velocity, and variable datasets that need to be managed at the right…

Distributed, Parallel, and Cluster Computing · Computer Science 2019-08-13 Youssef Bassil