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Parametric imaging is a compartmental approach that processes nuclear imaging data to estimate the spatial distribution of the kinetic parameters governing tracer flow. The present paper proposes a novel and efficient computational method…

Numerical Analysis · Mathematics 2018-08-21 Mara Scussolini , Sara Garbarino , Gianmario Sambuceti , Giacomo Caviglia , Michele Piana

Monte Carlo simulation is an essential tool in emission tomography that can assist in the design of new medical imaging devices, the optimization of acquisition protocols, and the development or assessment of image reconstruction algorithms…

We present {\gamma} spectroscopy validation measurements for the Geant4 radioactive decay simulation for a selected range of isotopes using a simple experimental setup. Using these results we point out problems in the decay simulation and…

Computational Physics · Physics 2010-12-02 S. Hauf , M. Kuster , Dieter H. H. Hoffmann , Z. W. Bell , M. G. Pia , Georg Weidenspointner , A. Zoglauer

Geant4-based simulations of the energy deposited by electrons in various materials are quantitatively compared to high precision calorimetric measurements taken at Sandia Laboratories. The experimental data concern electron beams of energy…

Computational Physics · Physics 2015-06-16 Matej Batic , Gabriela Hoff , Maria Grazia Pia , Paolo Saracco , Georg Weidenspointner

Positron Emission Tomography (PET) is an imaging method that can assess physiological function rather than structural disturbances by measuring cerebral perfusion or glucose consumption. However, this imaging technique relies on injection…

Image and Video Processing · Electrical Eng. & Systems 2021-03-10 Sahar Yousefi , Hessam Sokooti , Wouter M. Teeuwisse , Dennis F. R. Heijtel , Aart J. Nederveen , Marius Staring , Matthias J. P. van Osch

Positron Emission Tomography (PET) image reconstruction is inherently challenged by Poisson noise and physical degradation factors, which are further exacerbated in limited-angle acquisitions. While deep learning methods demonstrate…

Computer Vision and Pattern Recognition · Computer Science 2026-05-11 Rüveyda Yilmaz , Yuli Wu , Johannes Stegmaier , Volkmar Schulz

Positron Emission Tomography (PET) enables functional imaging of deep brain structures, but the bulk and weight of current systems preclude their use during many natural human activities, such as locomotion. The proposed long-term solution…

Robotics · Computer Science 2023-12-07 Junxiang Wang , Ti Wu , Iulian I. Iordachita , Peter Kazanzides

The program Simourg (Simulator of Usually Requested Geometries) is based on the Geant4 toolkit and created for Monte Carlo simulation of gamma-ray spectrometric nuclear detectors with a simple axial symmetric geometry, which is typical for…

Instrumentation and Detectors · Physics 2025-12-09 V. V. Kobychev

Geant4 is a tool kit developed by a collaboration of physicists and computer professionals in the High Energy Physics field for simulation of the passage of particles through matter. The motivation for the development of the Beam Tools is…

High Energy Physics - Experiment · Physics 2007-05-23 V. Daniel Elvira , P. Lebrun , P. Spentzouris

Tumor lesion segmentation is one of the most important tasks in medical image analysis. In clinical practice, Fluorodeoxyglucose Positron-Emission Tomography~(FDG-PET) is a widely used technique to identify and quantify metabolically active…

Image and Video Processing · Electrical Eng. & Systems 2022-10-17 Jin Ye , Haoyu Wang , Ziyan Huang , Zhongying Deng , Yanzhou Su , Can Tu , Qian Wu , Yuncheng Yang , Meng Wei , Jingqi Niu , Junjun He

The low cost and high resolution gas-based Multi-gap Resistive Plate Chamber (MRPC) opens a new possibility to find an efficient alternative detector for Time of Flight (TOF) based Positron Emission Tomography, where the sensitivity of the…

Instrumentation and Detectors · Physics 2011-06-30 A. Banerjee , S. Chattopadhyay

KM2A is one of the main sub-arrays of LHAASO, working on gamma ray astronomy and cosmic ray physics at energies above 10 TeV. Detector simulation is the important foundation for estimating detector performance and data analysis. It is a big…

Instrumentation and Methods for Astrophysics · Physics 2024-05-14 Zhen Cao , F. Aharonian , Q. An , Axikegu , Y. X. Bai , Y. W. Bao , D. Bastieri , X. J. Bi , Y. J. Bi , J. T. Cai , Q. Cao , W. Y. Cao , Zhe Cao , J. Chang , J. F. Chang , A. M. Chen , E. S. Chen , Liang Chen , Lin Chen , Long Chen , M. J. Chen , M. L. Chen , Q. H. Chen , S. H. Chen , S. Z. Chen , T. L. Chen , Y. Chen , N. Cheng , Y. D. Cheng , M. Y. Cui , S. W. Cui , X. H. Cui , Y. D. Cui , B. Z. Dai , H. L. Dai , Z. G. Dai , Danzengluobu , X. Q. Dong , K. K. Duan , J. H. Fan , Y. Z. Fan , J. Fang , K. Fang , C. F. Feng , L. Feng , S. H. Feng , X. T. Feng , Y. L. Feng , S. Gabici , B. Gao , C. D. Gao , L. Q. Gao , Q. Gao , W. Gao , W. K. Gao , M. M. Ge , L. S. Geng , G. Giacinti , G. H. Gong , Q. B. Gou , M. H. Gu , F. L. Guo , X. L. Guo , Y. Q. Guo , Y. Y. Guo , Y. A. Han , H. H. He , H. N. He , J. Y. He , X. B. He , Y. He , Y. K. Hor , B. W. Hou , C. Hou , X. Hou , H. B. Hu , Q. Hu , S. C. Hu , D. H. Huang , T. Q. Huang , W. J. Huang , X. T. Huang , X. Y. Huang , Y. Huang , Z. C. Huang , X. L. Ji , H. Y. Jia , K. Jia , K. Jiang , X. W. Jiang , Z. J. Jiang , M. Jin , M. M. Kang , T. Ke , D. Kuleshov , K. Kurinov , B. B. Li , Cheng Li , Cong Li , D. Li , F. Li , H. B. Li , H. C. Li , H. Y. Li , J. Li , Jian Li , Jie Li , K. Li , W. L. Li , W. L. Li , X. R. Li , Xin Li , Y. Z. Li , Zhe Li , Zhuo Li , E. W. Liang , Y. F. Liang , J. Lin , B. Liu , C. Liu , D. Liu , H. Liu , H. D. Liu , J. Liu , J. L. Liu , J. Y. Liu , M. Y. Liu , R. Y. Liu , S. M. Liu , W. Liu , Y. Liu , Y. N. Liu , R. Lu , Q. Luo , H. K. Lv , B. Q. Ma , L. L. Ma , X. H. Ma , J. R. Mao , Z. Min , W. Mitthumsiri , H. J. Mu , Y. C. Nan , A. Neronov , Z. W. Ou , B. Y. Pang , P. Pattarakijwanich , Z. Y. Pei , M. Y. Qi , Y. Q. Qi , B. Q. Qiao , J. J. Qin , D. Ruffolo , A. Sáiz , D. Semikoz , C. Y. Shao , L. Shao , O. Shchegolev , X. D. Sheng , F. W. Shu , H. C. Song , Yu. V. Stenkin , V. Stepanov , Y. Su , Q. N. Sun , X. N. Sun , Z. B. Sun , P. H. T. Tam , Q. W. Tang , Z. B. Tang , W. W. Tian , C. Wang , C. B. Wang , G. W. Wang , H. G. Wang , H. H. Wang , J. C. Wang , K. Wang , L. P. Wang , L. Y. Wang , P. H. Wang , R. Wang , W. Wang , X. G. Wang , X. Y. Wang , Y. Wang , Y. D. Wang , Y. J. Wang , Z. H. Wang , Z. X. Wang , Zhen Wang , Zheng Wang , D. M. Wei , J. J. Wei , Y. J. Wei , T. Wen , C. Y. Wu , H. R. Wu , S. Wu , X. F. Wu , Y. S. Wu , S. Q. Xi , J. Xia , J. J. Xia , G. M. Xiang , D. X. Xiao , G. Xiao , G. G. Xin , Y. L. Xin , Y. Xing , Z. Xiong , D. L. Xu , R. F. Xu , R. X. Xu , W. L. Xu , L. Xue , D. H. Yan , J. Z. Yan , T. Yan , C. W. Yang , F. Yang , F. F. Yang , H. W. Yang , J. Y. Yang , L. L. Yang , M. J. Yang , R. Z. Yang , S. B. Yang , Y. H. Yao , Z. G. Yao , Y. M. Ye , L. Q. Yin , N. Yin , X. H. You , Z. Y. You , Y. H. Yu , Q. Yuan , H. Yue , H. D. Zeng , T. X. Zeng , W. Zeng , M. Zha , B. B. Zhang , F. Zhang , H. M. Zhang , H. Y. Zhang , J. L. Zhang , L. X. Zhang , Li Zhang , P. F. Zhang , P. P. Zhang , R. Zhang , S. B. Zhang , S. R. Zhang , S. S. Zhang , X. Zhang , X. P. Zhang , Y. F. Zhang , Yi Zhang , Yong Zhang , B. Zhao , J. Zhao , L. Zhao , L. Z. Zhao , S. P. Zhao , F. Zheng , J. H. Zheng , B. Zhou , H. Zhou , J. N. Zhou , M. Zhou , P. Zhou , R. Zhou , X. X. Zhou , C. G. Zhu , F. R. Zhu , H. Zhu , K. J. Zhu , X. Zuo

The construction of modern detectors used in high-energy physics experiments is typically guided by modeling with the Geant4 toolkit to evaluate detector performance in terms of geometrical acceptance and detection efficiency. Several…

Instrumentation and Detectors · Physics 2026-01-05 S. D. Savenkov , A. O. Svetlichnyi , I. A. Pshenichnov

The Generic Geant4 Simulation (GGS) is a package designed to speed-up the realization and deployment of Monte Carlo simulation software based on Geant4, for small- and medium-sized high-energy experiments. For many common use cases, the…

Data Analysis, Statistics and Probability · Physics 2021-04-22 Nicola Mori

Positron Emission Tomography (PET) scanners are usually designed with the goal to obtain the best compromise between sensitivity, resolution, field-of-view size, and cost. Therefore, it is difficult to improve the resolution of a PET…

Medical Physics · Physics 2023-07-18 Pablo Galve , Alejandro Lopez-Montes , Jose M Udias , Stephen C Moore , Joaquin L Herraiz

To improve the quality of cancer treatment with protons, a translation of X-ray Computed Tomography (CT) images into a map of the proton stopping powers needs to be more accurate. Proton stopping powers determined from CT images have…

A NEMA performance evaluation was conducted on the new General Electric (GE) digital Omni Legend PET-CT system with 32-cm extended field-of-view. This study marks the introduction of the first-ever commercially available clinical digital…

We compare existing segmented plastic antineutrino detectors with our new geometrically improved design for antineutrino detection and light collection efficiency. The purpose of this study is to determine the most suitable design style for…

Instrumentation and Detectors · Physics 2019-03-07 Mustafa Kandemir , Altan Cakir

The imaging performance of a high-resolution preclinical microPET system employing liquid xenon as the gamma ray detection medium was simulated. The arrangement comprises a ring of detectors consisting of trapezoidal LXe time projection…

Medical Physics · Physics 2012-03-23 A. Miceli , J. Glister , A. Andreyev , D. Bryman , L. Kurchaninov , P. Lu , A. Muennich , F. Retiere , V. Sossi

The present paper proposes a novel computational method for parametric imaging of nuclear medicine data. The mathematical procedure is general enough to work for compartmental models of diverse complexity and is effective in the…

Tissues and Organs · Quantitative Biology 2017-05-15 Mara Scussolini , Sara Garbarino , Gianmario Sambuceti , Giacomo Caviglia , Michele Piana