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We reconstructed the 3D Fourier intensity distribution of mono-disperse prolate nano-particles using single-shot 2D coherent diffraction patterns collected at DESY's FLASH facility when a bright, coherent, ultrafast X-ray pulse intercepted…

Understanding the structure of a protein complex is crucial indetermining its function. However, retrieving accurate 3D structures from microscopy images is highly challenging, particularly as many imaging modalities are two-dimensional.…

Quantitative Methods · Quantitative Biology 2021-10-18 Benjamin J. Blundell , Christian Sieben , Suliana Manley , Ed Rosten , QueeLim Ch'ng , Susan Cox

A major challenge in single-particle cryo-electron microscopy (cryo-EM) is that the orientations adopted by the 3D particles prior to imaging are unknown; yet, this knowledge is essential for high-resolution reconstruction. We present a…

Machine Learning · Computer Science 2021-04-14 Jelena Banjac , Laurène Donati , Michaël Defferrard

We study a nonlinear Schr\"odinger equation which arises as an effective single particle model in X-ray Free Electron Lasers (XFEL). This equation appears as a first-principles model for the beam-matter interactions that would take place in…

Numerical Analysis · Mathematics 2014-06-18 Paolo Antonelli , Agissilaos Athanassoulis , Zhongyi Huang , Peter A. Markowich

Tailoring nanoparticles composition and morphology is of particular interest for improving their performance for catalysis. A challenge of this approach is that the nanoparticles optimized initial structure often changes during use.…

Scanning X-ray nanodiffraction microscopy is a powerful technique for spatially resolving nanoscale structural morphologies by diffraction contrast. One of the critical challenges in experimental nanodiffraction data analysis is posed by…

Applied Physics · Physics 2024-06-26 Aileen Luo , Tao Zhou , Martin V. Holt , Andrej Singer , Mathew J. Cherukara

Single-Photon Image Super-Resolution (SPISR) aims to recover a high-resolution volumetric photon counting cube from a noisy low-resolution one by computational imaging algorithms. In real-world scenarios, pairs of training samples are often…

Image and Video Processing · Electrical Eng. & Systems 2023-03-06 Yiwei Chen , Chen Jiang , Yu Pan

Among the major remaining challenges for single image super resolution (SISR) is the capacity to recover coherent images with global shapes and local details conforming to human vision system. Recent generative adversarial network (GAN)…

Image and Video Processing · Electrical Eng. & Systems 2021-01-26 Yuanzhuo Li , Yunan Zheng , Jie Chen , Zhenyu Xu , Yiguang Liu

Recently introduced speckle-correlations based techniques enable noninvasive imaging of objects hidden behind scattering layers. In these techniques the hidden object Fourier amplitude is retrieved from the scattered light autocorrelation,…

Optics · Physics 2022-01-19 Tengfei Wu , Ori Katz , Xiaopeng Shao , Sylvain Gigan

X-ray ptychography is one of the versatile techniques for nanometer resolution imaging. The magnitude of the diffraction patterns is recorded on a detector and the phase of the diffraction patterns is estimated using phase retrieval…

Image and Video Processing · Electrical Eng. & Systems 2021-05-21 Prasan Shedligeri , Florian Schiffers , Semih Barutcu , Pablo Ruiz , Aggelos K Katsaggelos , Oliver Cossairt

Four-dimensional scanning transmission electron microscopy (4D-STEM) of local atomic diffraction patterns is emerging as a powerful technique for probing intricate details of atomic structure and atomic electric fields. However, efficient…

Image and Video Processing · Electrical Eng. & Systems 2019-01-15 Xin Li , Ondrej E. Dyck , Mark P. Oxley , Andrew R. Lupini , Leland McInnes , John Healy , Stephen Jesse , Sergei V. Kalinin

This paper presents a Multispectral imaging (MSI) approach that combines the use of a diffractive optical element, and a deep learning algorithm for spectral reconstruction. Traditional MSI techniques often face challenges such as high…

Image and Video Processing · Electrical Eng. & Systems 2023-10-06 Khen Cohen , Tuval Kay

The sparse layouts of radio interferometers result in an incomplete sampling of the sky in Fourier space which leads to artifacts in the reconstructed images. Cleaning these systematic effects is essential for the scientific use of…

Instrumentation and Methods for Astrophysics · Physics 2023-07-27 Kevin Schmidt , Felix Geyer , Stefan Fröse , Paul-Simon Blomenkamp , Marcus Brüggen , Francesco de Gasperin , Dominik Elsässer , Wolfgang Rhode

The Single Particles, Clusters and Biomolecules (SPB) instrument at the European XFEL is located behind the SASE1 undulator, and aims to support imaging and structure determination of biological specimen between about 0.1 micrometer and 1…

To reduce scanning time and/or improve spatial/temporal resolution in some MRI applications, parallel MRI (pMRI) acquisition techniques with multiple coils acquisition have emerged since the early 1990s as powerful 3D imaging methods that…

Optimization and Control · Mathematics 2009-09-03 Lotfi Chaari , Jean-Christophe Pesquet , Philippe Ciuciu , Amel Benazza-Benyahia

Magnetic Particle Imaging (MPI) is a promising noninvasive in vivo imaging modality that makes it possible to map the spatial distribution of superparamagnetic nanoparticles by exposing them to dynamic magnetic fields. In the Field-Free…

Numerical Analysis · Mathematics 2025-08-08 Vladyslav Gapyak , Thomas März , Andreas Weinmann

The resolution of X-ray diffraction microscopy is limited by the maximum dose that can be delivered prior to sample damage. In the proposed Serial Crystallography method, the damage problem is addressed by distributing the total dose over…

Reconstructing unbounded outdoor scenes from sparse outward-facing views poses significant challenges due to minimal view overlap. Previous methods often lack cross-scene understanding and their primitive-centric formulations overload local…

Computer Vision and Pattern Recognition · Computer Science 2025-02-07 Eyvaz Najafli , Marius Kästingschäfer , Sebastian Bernhard , Thomas Brox , Andreas Geiger

Recovering the 3D structure of the scene from images yields useful information for tasks such as shape and scene recognition, object detection, or motion planning and object grasping in robotics. In this thesis, we introduce a general…

Computer Vision and Pattern Recognition · Computer Science 2010-07-20 Hoang Trinh

The core theme of X-ray crystallography is reconstructing the electron density distribution of crystals under the constraints of observed diffraction data. Nevertheless, the reconstruction of electron density distribution by straightforward…

Materials Science · Physics 2015-07-14 Hui Li , Meng He , Ze Zhang