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Semi-supervised learning has been employed to alleviate the need for extensive labeled data for histopathology image segmentation, but existing methods struggle with noisy pseudo-labels due to ambiguous gland boundaries and morphological…

Computer Vision and Pattern Recognition · Computer Science 2025-09-18 Nguyen Lan Vi Vu , Thanh-Huy Nguyen , Thien Nguyen , Daisuke Kihara , Tianyang Wang , Xingjian Li , Min Xu

Semi-supervised semantic segmentation involves assigning pixel-wise labels to unlabeled images at training time. This is useful in a wide range of real-world applications where collecting pixel-wise labels is not feasible in time or cost.…

Computer Vision and Pattern Recognition · Computer Science 2023-08-08 Jianfeng Wang , Daniela Massiceti , Xiaolin Hu , Vladimir Pavlovic , Thomas Lukasiewicz

Automatic histopathology image segmentation is crucial to disease analysis. Limited available labeled data hinders the generalizability of trained models under the fully supervised setting. Semi-supervised learning (SSL) based on generative…

Computer Vision and Pattern Recognition · Computer Science 2020-12-18 Hongxiao Wang , Hao Zheng , Jianxu Chen , Lin Yang , Yizhe Zhang , Danny Z. Chen

Semi-supervised learning relaxes the need of large pixel-wise labeled datasets for image segmentation by leveraging unlabeled data. A prominent way to exploit unlabeled data is to regularize model predictions. Since the predictions of…

Computer Vision and Pattern Recognition · Computer Science 2023-10-26 Sukesh Adiga , Jose Dolz , Herve Lombaert

The application of deep learning to medical image segmentation has been hampered due to the lack of abundant pixel-level annotated data. Few-shot Semantic Segmentation (FSS) is a promising strategy for breaking the deadlock. However, a…

Computer Vision and Pattern Recognition · Computer Science 2021-10-26 Xiaoang Shen , Guokai Zhang , Huilin Lai , Jihao Luo , Jianwei Lu , Ye Luo

The performance of supervised deep learning methods for medical image segmentation is often limited by the scarcity of labeled data. As a promising research direction, semi-supervised learning addresses this dilemma by leveraging unlabeled…

Image and Video Processing · Electrical Eng. & Systems 2024-05-13 Zihang Liu , Chunhui Zhao

Training a neural network with a large labeled dataset is still a dominant paradigm in computational histopathology. However, obtaining such exhaustive manual annotations is often expensive, laborious, and prone to inter and Intra-observer…

Computer Vision and Pattern Recognition · Computer Science 2021-11-03 Chetan L. Srinidhi , Seung Wook Kim , Fu-Der Chen , Anne L. Martel

Semantic segmentation of various tissue and nuclei types in histology images is fundamental to many downstream tasks in the area of computational pathology (CPath). In recent years, Deep Learning (DL) methods have been shown to perform well…

Computer Vision and Pattern Recognition · Computer Science 2023-02-14 Raja Muhammad Saad Bashir , Talha Qaiser , Shan E Ahmed Raza , Nasir M. Rajpoot

Tissue semantic segmentation is one of the key tasks in computational pathology. To avoid the expensive and laborious acquisition of pixel-level annotations, a wide range of studies attempt to adopt the class activation map (CAM), a…

Computer Vision and Pattern Recognition · Computer Science 2024-12-31 Zijie Fang , Yifeng Wang , Peizhang Xie , Zhi Wang , Yongbing Zhang

Deep convolutional neural networks have achieved remarkable progress on a variety of medical image computing tasks. A common problem when applying supervised deep learning methods to medical images is the lack of labeled data, which is very…

Computer Vision and Pattern Recognition · Computer Science 2020-05-12 Xiaomeng Li , Lequan Yu , Hao Chen , Chi-Wing Fu , Lei Xing , Pheng-Ann Heng

In semi-supervised segmentation, capturing meaningful semantic structures from unlabeled data is essential. This is particularly challenging in histopathology image analysis, where objects are densely distributed. To address this issue, we…

Computer Vision and Pattern Recognition · Computer Science 2025-10-03 Meilong Xu , Xiaoling Hu , Shahira Abousamra , Chen Li , Chao Chen

Learning segmentation from noisy labels is an important task for medical image analysis due to the difficulty in acquiring highquality annotations. Most existing methods neglect the pixel correlation and structural prior in segmentation,…

Computer Vision and Pattern Recognition · Computer Science 2021-07-22 Shuailin Li , Zhitong Gao , Xuming He

Traditional supervised medical image segmentation models require large amounts of labeled data for training; however, obtaining such large-scale labeled datasets in the real world is extremely challenging. Recent semi-supervised…

Computer Vision and Pattern Recognition · Computer Science 2025-05-26 Yunyao Lu , Yihang Wu , Reem Kateb , Ahmad Chaddad

Semi-supervised learning (semi-SL) is a promising alternative to supervised learning for medical image analysis when obtaining good quality supervision for medical imaging is difficult. However, semi-SL assumes that the underlying…

Computer Vision and Pattern Recognition · Computer Science 2023-03-20 Nikhil Cherian Kurian , Varsha S , Abhijit Patil , Shashikant Khade , Amit Sethi

Biomedical image segmentation plays a significant role in computer-aided diagnosis. However, existing CNN based methods rely heavily on massive manual annotations, which are very expensive and require huge human resources. In this work, we…

Computer Vision and Pattern Recognition · Computer Science 2023-01-13 Ruifei Zhang , Sishuo Liu , Yizhou Yu , Guanbin Li

Supervised deep learning for semantic segmentation has achieved excellent results in accurately identifying anatomical and pathological structures in medical images. However, it often requires large annotated training datasets, which limits…

Computer Vision and Pattern Recognition · Computer Science 2026-03-11 Luca Ciampi , Gabriele Lagani , Giuseppe Amato , Fabrizio Falchi

Deep convolutional neural networks are widely used in medical image segmentation but require many labeled images for training. Annotating three-dimensional medical images is a time-consuming and costly process. To overcome this limitation,…

Computer Vision and Pattern Recognition · Computer Science 2024-07-08 Weiyi Xie , Nathalie Willems , Nikolas Lessmann , Tom Gibbons , Daniele De Massari

Noisy labels, inevitably existing in pseudo segmentation labels generated from weak object-level annotations, severely hampers model optimization for semantic segmentation. Previous works often rely on massive hand-crafted losses and…

Computer Vision and Pattern Recognition · Computer Science 2024-01-23 Shenwang Jiang , Jianan Li , Ying Wang , Wenxuan Wu , Jizhou Zhang , Bo Huang , Tingfa Xu

Obtaining pixel-level annotations in the medical domain is both expensive and time-consuming, often requiring close collaboration between clinical experts and developers. Semi-supervised medical image segmentation aims to leverage limited…

Computer Vision and Pattern Recognition · Computer Science 2025-07-23 Lin Xi , Yingliang Ma , Cheng Wang , Sandra Howell , Aldo Rinaldi , Kawal S. Rhode

Semi-supervised semantic segmentation in computational pathology remains challenging due to scarce pixel-level annotations and unreliable pseudo-label supervision. We propose UniSemAlign, a dual-modal semantic alignment framework that…

Computer Vision and Pattern Recognition · Computer Science 2026-04-13 Le-Van Thai , Tien Dat Nguyen , Hoai Nhan Pham , Lan Anh Dinh Thi , Duy-Dong Nguyen , Ngoc Lam Quang Bui
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