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We study the influence of the rate of the attainment of herd immunity (HI), in the absence of an approved vaccine, on the vulnerable population. We essentially ask the question: how hard the evolution towards the desired herd immunity could…

Populations and Evolution · Quantitative Biology 2020-06-01 Sayantan Mondal , Saumyak Mukherjee , Biman Bagchi

Driven by applications in telecommunication networks, we explore the simulation task of estimating rare event probabilities for tandem queues in their steady state. Existing literature has recognized that importance sampling methods can be…

Machine Learning · Computer Science 2025-04-22 Ruoning Zhao , Xinyun Chen

This paper provides a comprehensive analysis of variational inference in latent variable models for survival analysis, emphasizing the distinctive challenges associated with applying variational methods to survival data. We identify a…

Machine Learning · Computer Science 2025-06-05 Chuanhui Liu , Xiao Wang

Mathematical models are invaluable for understanding and predicting how biological systems behave, although their construction requires specifying mechanisms and relationships that are often not perfectly known. In the presence of multiple…

Since survival data occur over time, often important covariates that we wish to consider also change over time. Such covariates are referred as time-dependent covariates. Quantile regression offers flexible modeling of survival data by…

Methodology · Statistics 2014-05-01 Malka Gorfine , Yair Goldberg , Yaacov Ritov

Support vector machines (SVMs) are widely used and constitute one of the best examined and used machine learning models for two-class classification. Classification in SVM is based on a score procedure, yielding a deterministic…

Machine Learning · Statistics 2023-10-11 Sandra Benítez-Peña , Rafael Blanquero , Emilio Carrizosa , Pepa Ramírez-Cobo

Estimating the importance of variables is an essential task in modern machine learning. This help to evaluate the goodness of a feature in a given model. Several techniques for estimating the importance of variables have been developed…

Machine Learning · Statistics 2022-08-09 Louis Mozart Kamdem , Ernest Fokoue

In survival studies it is important to record the values of key longitudinal covariates until the occurrence of event of a subject. For this reason, it is essential to study the association between longitudinal and time-to-event outcomes…

Methodology · Statistics 2021-06-09 Khandoker Akib Mohammad , Yuichi Hirose , Yuan Yao , Budhi Surya

In many real-world scenarios where data is high dimensional, test time acquisition of features is a non-trivial task due to costs associated with feature acquisition and evaluating feature value. The need for highly confident models with an…

Machine Learning · Computer Science 2019-09-17 Orpaz Goldstein , Mohammad Kachuee , Kimmo Karkkainen , Majid Sarrafzadeh

Machine learning has revolutionized numerous domains, playing a crucial role in driving advancements and enabling data-centric processes. The significance of data in training models and shaping their performance cannot be overstated. Recent…

Cryptography and Security · Computer Science 2024-10-01 Rui Wen , Michael Backes , Yang Zhang

We propose a class of two-sample statistics for testing the equality of proportions and the equality of survival functions. We build our proposal on a weighted combination of a score test for the difference in proportions and a Weighted…

Methodology · Statistics 2021-12-08 Marta Bofill Roig , Guadalupe Gómez Melis

A common problem in machine learning is determining if a variable significantly contributes to a model's prediction performance. This problem is aggravated for datasets, such as gene expression datasets, that suffer the worst case of…

Methodology · Statistics 2023-10-13 Yue Wu , Ted Spaide , Kenji Nakamichi , Russell Van Gelder , Aaron Lee

When search methods are being designed it is very important to know which parameters have the greatest influence on the behaviour and performance of the algorithm. To this end, algorithm parameters are commonly calibrated by means of either…

The Hazard Ratio (HR) is often reported as the main causal effect when studying survival data. Despite its popularity, the HR suffers from an unclear causal interpretation. As already pointed out in the literature, there is a built-in…

Methodology · Statistics 2022-03-08 Rachel Axelrod , Daniel Nevo

The goal of this presentation is to build an efficient non-parametric Bayes classifier in the presence of large numbers of predictors. When analyzing such data, parametric models are often too inflexible while non-parametric procedures tend…

Methodology · Statistics 2013-01-07 Abhishek Bhattacharya

We introduce a semi-parametric Bayesian model for survival analysis. The model is centred on a parametric baseline hazard, and uses a Gaussian process to model variations away from it nonparametrically, as well as dependence on covariates.…

Machine Learning · Statistics 2016-11-04 Tamara Fernández , Nicolás Rivera , Yee Whye Teh

Survival outcomes are common in comparative effectiveness studies and require unique handling because they are usually incompletely observed due to right-censoring. A ``once for all'' approach for causal inference with survival outcomes…

Methodology · Statistics 2021-12-21 Shuxi Zeng , Fan Li , Liangyuan Hu , Fan Li

Previous deep learning approaches for survival analysis have primarily relied on ranking losses to improve discrimination performance, which often comes at the expense of calibration performance. To address such an issue, we propose a novel…

Machine Learning · Computer Science 2024-11-22 Dongjoon Lee , Hyeryn Park , Changhee Lee

A common approach for feature selection is to examine the variable importance scores for a machine learning model, as a way to understand which features are the most relevant for making predictions. Given the significance of feature…

Machine Learning · Computer Science 2021-05-13 Jack Dunn , Luca Mingardi , Ying Daisy Zhuo

When dealing with right-censored data, where some outcomes are missing due to a limited observation period, survival analysis -- known as time-to-event analysis -- focuses on predicting the time until an event of interest occurs. Multiple…

Machine Learning · Statistics 2024-10-23 Julie Alberge , Vincent Maladière , Olivier Grisel , Judith Abécassis , Gaël Varoquaux