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The development of machine learned potentials for catalyst discovery has predominantly been focused on very specific chemistries and material compositions. While effective in interpolating between available materials, these approaches…

De novo design seeks to generate molecules with required property profiles by virtual design-make-test cycles. With the emergence of deep learning and neural generative models in many application areas, models for molecular design based on…

Quantitative Methods · Quantitative Biology 2021-01-05 Nathan Brown , Marco Fiscato , Marwin H. S. Segler , Alain C. Vaucher

This volume contains the papers presented at the Tenth International Workshop on Developments in Computational Models (DCM) held in Vienna, Austria on 13th July 2014, as part of the Vienna Summer of Logic. Several new models of computation…

Logic in Computer Science · Computer Science 2015-04-09 Ugo Dal Lago , Russ Harmer

In this work we apply methods for describing 3D images to the problem of encoding atomic environments in a way that is invariant to rotations, translations, and permutations of the atoms and, crucially, can be decoded back into the original…

Materials Science · Physics 2021-10-28 Martin Uhrin

The quantum separability problem consists in deciding whether a bipartite density matrix is entangled or separable. In this work, we propose a machine learning pipeline for finding approximate solutions for this NP-hard problem in…

Quantum Physics · Physics 2023-12-12 Balthazar Casalé , Giuseppe Di Molfetta , Sandrine Anthoine , Hachem Kadri

Electrochemistry workflows utilize various instruments and computing systems to execute workflows consisting of electrocatalyst synthesis, testing and evaluation tasks. The heterogeneity of the software and hardware of these ecosystems…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-01-15 Anees Al-Najjar , Nageswara S. V. Rao , Craig A. Bridges , Sheng Dai , Alex Walters

Expanding genetic codes from natural standard nucleotides to artificial non-standard nucleotides marks a significant advancement in synthetic biology, with profound implications for biotechnology and medicine. Decoding the biological…

Genomics · Quantitative Biology 2024-09-17 Hyunjin Shim

Owing to the computational complexity of electronic structure algorithms running on classical digital computers, the range of molecular systems amenable to simulation remains tightly circumscribed even after many decades of work. Quantum…

Quantum Physics · Physics 2022-05-18 Alexis Ralli , Michael I. Williams , Peter V. Coveney

Protocol standardization and sharing are crucial for reproducibility in life sciences. In spite of numerous efforts for standardized protocol description, adherence to these standards in literature remains largely inconsistent. Curation of…

Quantitative Methods · Quantitative Biology 2023-12-12 Shuo Jiang , Daniel Evans-Yamamoto , Dennis Bersenev , Sucheendra K. Palaniappan , Ayako Yachie-Kinoshita

Molecular property prediction (MPP) is a fundamental and crucial task in drug discovery. However, prior methods are limited by the requirement for a large number of labeled molecules and their restricted ability to generalize for unseen and…

Quantitative Methods · Quantitative Biology 2024-10-21 Yuyan Liu , Sirui Ding , Sheng Zhou , Wenqi Fan , Qiaoyu Tan

Ultra-reliable low-latency communications (URLLC) demand high-performance error-correcting codes and decoders in the finite blocklength regime. This letter introduces a novel two-stage near-maximum likelihood (near-ML) decoding framework…

Signal Processing · Electrical Eng. & Systems 2026-02-10 Yubeen Jo , Geon Choi , Yongjune Kim , Namyoon Lee

Test-time scaling has emerged as a powerful paradigm for enhancing the reasoning capabilities of large language models (LLMs) by allocating additional computational resources during inference. However, this paradigm is inherently…

Computation and Language · Computer Science 2025-09-08 Shengyin Sun , Yiming Li , Xing Li , Yingzhao Lian , Weizhe Lin , Hui-Ling Zhen , Zhiyuan Yang , Chen Chen , Xianzhi Yu , Mingxuan Yuan , Chen Ma

Complex organic molecules (COMs) are observed to be abundant in various astrophysical environments, in particular toward star forming regions they are observed both toward protostellar envelopes as well as shocked regions. Emission spectrum…

Instrumentation and Methods for Astrophysics · Physics 2026-01-14 Nina Kessler , Timea Csengeri , David Cornu , Sylvain Bontemps , Laure Bouscasse

In biological research machine learning algorithms are part of nearly every analytical process. They are used to identify new insights into biological phenomena, interpret data, provide molecular diagnosis for diseases and develop…

With the recent advances in machine learning for quantum chemistry, it is now possible to predict the chemical properties of compounds and to generate novel molecules. Existing generative models mostly use a string- or graph-based…

Biomolecules · Quantitative Biology 2020-10-14 Vitali Nesterov , Mario Wieser , Volker Roth

Wolumes is a fast and stand-alone computer program written in standard C that allows the measure of atom volumes in proteins. Its algorithm is a simple discretization of the space by means of a grid of points at 0.75 Angstroms from each…

Biomolecules · Quantitative Biology 2014-06-13 Oliviero Carugo

The extraction of molecular structures and reaction data from scientific documents is challenging due to their varied, unstructured chemical formats and complex document layouts. To address this, we introduce MolMole, a vision-based deep…

Recent breakthroughs by deep neural networks (DNNs) in natural language processing (NLP) and computer vision have been driven by a scale-up of models and data rather than the discovery of novel computing paradigms. Here, we investigate if…

Molecular property prediction integrates quantum chemistry, cheminformatics, and deep learning to connect molecular structure with physicochemical and biological behavior. This survey traces four complementary paradigms, including Quantum,…

A network of nanomachines (NMs) can be used to build a target detection system for a variety of promising applications. They have the potential to detect toxic chemicals, infectious bacteria, and biomarkers of dangerous diseases such as…

Information Theory · Computer Science 2024-01-10 Nithin V. Sabu , Abhishek K. Gupta