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A variety of approaches using compartmental models have been used to study the COVID-19 pandemic and the usage of machine learning methods with these models has had particularly notable success. We present here an approach toward analyzing…

Populations and Evolution · Quantitative Biology 2022-08-19 Haoran Hu , Connor M Kennedy , Panayotis G. Kevrekidis , Hongkun Zhang

The COVID-19 pandemic has highlighted the need for quantitative modeling and analysis to understand real-world disease dynamics. In particular, post hoc analyses using compartmental models offer valuable insights into the effectiveness of…

Machine Learning · Computer Science 2025-10-09 Phillip Rothenbeck , Sai Karthikeya Vemuri , Niklas Penzel , Joachim Denzler

Accurate forecasting of contagious diseases is critical for public health policymaking and pandemic preparedness. We propose a new infectious disease forecasting model based on physics-informed neural networks (PINNs), an emerging…

Machine Learning · Computer Science 2025-04-30 Ying Qian , Kui Zhang , Éric Marty , Avranil Basu , Eamon B. O'Dea , Xianqiao Wang , Spencer Fox , Pejman Rohani , John M. Drake , He Li

A physics-informed neural network (PINN) embedded with the susceptible-infected-removed (SIR) model is devised to understand the temporal evolution dynamics of infectious diseases. Firstly, the effectiveness of this approach is demonstrated…

Quantitative Methods · Quantitative Biology 2025-04-08 Shuai Han , Lukas Stelz , Horst Stoecker , Lingxiao Wang , Kai Zhou

Data-driven deep learning provides efficient algorithms for parameter identification of epidemiology models. Unlike the constant parameters, the complexity of identifying time-varying parameters is largely increased. In this paper, a…

Dynamical Systems · Mathematics 2021-03-19 Jie Long , Abdul Khaliq , Khaled Furati

Forecasting temporal processes such as virus spreading in epidemics often requires more than just observed time-series data, especially at the beginning of a wave when data is limited. Traditional methods employ mechanistic models like the…

Artificial Intelligence · Computer Science 2024-11-12 Thang Nguyen , Dung Nguyen , Kha Pham , Truyen Tran

This work introduces a physics-informed neural networks (PINNs)-based model predictive control (MPC) framework for susceptible-infected-recovered ($SIR$) spreading models. Existing studies in MPC design for epidemic control often assume…

Machine Learning · Computer Science 2025-09-17 Aiping Zhong , Baike She , Philip E. Paré

Physics-Informed Neural Network (PINN) is a deep learning framework that integrates the governing equations underlying data into a loss function. In this study, we consider the problem of estimating state variables and parameters in…

Symbolic Computation · Computer Science 2025-08-07 Mizuka Komatsu

When investigating epidemic dynamics through differential models, the parameters needed to understand the phenomenon and to simulate forecast scenarios require a delicate calibration phase, often made even more challenging by the scarcity…

Numerical Analysis · Mathematics 2023-09-11 Giulia Bertaglia , Chuan Lu , Lorenzo Pareschi , Xueyu Zhu

Reaction-diffusion epidemic models with vital dynamics are an important framework for describing the spatial and temporal spread of infectious diseases. In this work, we present a constraint-aware, physics-informed neural network (PINN)…

Dynamical Systems · Mathematics 2026-05-20 Achraf Zinihi , Matthias Ehrhardt

Physics-informed neural networks (PINNs) have emerged as a promising approach to solving partial differential equations (PDEs) using neural networks, particularly in data-scarce scenarios, due to their unsupervised training capability.…

Machine Learning · Computer Science 2025-03-25 Edgar Torres , Jonathan Schiefer , Mathias Niepert

Accurate epidemic forecasting is critical for informing public health decisions and timely interventions. While Physics-Informed Neural Networks have shown promise in various scientific domains, their potential application to real-time…

Physics and Society · Physics 2026-05-20 Martina Rama , Gabriele Santin , Giulia Cencetti , Michele Tizzoni , Bruno Lepri

The accurate modelling of structural dynamics is crucial across numerous engineering applications, such as Structural Health Monitoring (SHM), seismic analysis, and vibration control. Often, these models originate from physics-based…

Computational Physics · Physics 2024-10-31 Marcus Haywood-Alexander , Giacomo Arcieri , Antonios Kamariotis , Eleni Chatzi

The spread of many infectious diseases is modeled using variants of the SIR compartmental model, which is a coupled differential equation. The coefficients of the SIR model determine the spread trajectories of disease, on whose basis…

Machine Learning · Computer Science 2023-03-28 Ritam Majumdar , Shirish Karande , Lovekesh Vig

We develop a physics-informed neural network (PINN) framework for parameter estimation in fractional-order SEIRD epidemic models. By embedding the Caputo fractional derivative into the network residuals via the L1 discretization scheme, our…

Machine Learning · Statistics 2025-09-30 Achraf Zinihi

Physics-informed neural networks (PINNs) provide a powerful framework for learning governing equations of dynamical systems from data. Biologically-informed neural networks (BINNs) are a variant of PINNs that preserve the known differential…

Machine Learning · Computer Science 2026-04-21 William Lavery , Jodie A. Cochrane , Christian Olesen , Dagim S. Tadele , John T. Nardini , Sara Hamis

Physics-informed neural networks (PINNs) have shown promising potential for solving partial differential equations (PDEs) using deep learning. However, PINNs face training difficulties for evolutionary PDEs, particularly for dynamical…

Neural and Evolutionary Computing · Computer Science 2023-12-25 Siqi Chen , Bin Shan , Ye Li

This work focuses on understanding the minimum eradication time for the controlled Susceptible-Infectious-Recovered (SIR) model in the time-homogeneous setting, where the infection and recovery rates are constant. The eradication time is…

Optimization and Control · Mathematics 2026-01-27 Minseok Kim , Yeongjong Kim , Yeoneung Kim

In this work, we present an approach called Disease Informed Neural Networks (DINNs) that can be employed to effectively predict the spread of infectious diseases. This approach builds on a successful physics informed neural network…

Machine Learning · Computer Science 2022-08-26 Sagi Shaier , Maziar Raissi , Padmanabhan Seshaiyer

In this study, we considered the problem of estimating epidemiological parameters based on physics-informed neural networks (PINNs). In practice, not all trajectory data corresponding to the population estimated by epidemic models can be…

Machine Learning · Computer Science 2024-07-18 Mizuka Komatsu
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