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Related papers: Soft Phenotyping for Sepsis via EHR Time-aware Sof…

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Visual summarization of clinical data collected on patients contained within the electronic health record (EHR) may enable precise and rapid triage at the time of patient presentation to an emergency department (ED). The triage process is…

Human-Computer Interaction · Computer Science 2019-07-26 Nathan C. Hurley , Adrian D. Haimovich , R. Andrew Taylor , Bobak J. Mortazavi

The progression of complex human diseases is associated with critical transitions across dynamical regimes. These transitions often spawn early-warning signals and provide insights into the underlying disease-driving mechanisms. In this…

Quantitative Methods · Quantitative Biology 2019-10-24 Pejman F. Ghalati , Satya S. Samal , Jayesh S. Bhat , Robert Deisz , Gernot Marx , Andreas Schuppert

Sepsis is a leading cause of mortality in intensive care units (ICUs), yet existing research often relies on outdated datasets, non-reproducible preprocessing pipelines, and limited coverage of clinical interventions. We introduce…

Machine Learning · Computer Science 2025-10-29 Yong Huang , Zhongqi Yang , Amir Rahmani

Epilepsy is a prevalent neurological disorder globally, impacting around 50 million people \cite{WHO_epilepsy_50million}. Epileptic seizures result from sudden abnormal electrical activity in the brain, which can be read as sudden and…

Machine Learning · Computer Science 2025-08-15 Mohammed Guhdar , Ramadhan J. Mstafa , Abdulhakeem O. Mohammed

Ensembling neural networks is a long-standing technique for improving the generalization error of neural networks by combining networks with orthogonal properties via a committee decision. We show that this technique is an ideal fit for…

Machine Learning · Computer Science 2023-06-12 Shigehiko Schamoni , Michael Hagmann , Stefan Riezler

Due to the wider availability of modern electronic health records, patient care data is often being stored in the form of time-series. Clustering such time-series data is crucial for patient phenotyping, anticipating patients' prognoses by…

Medical Physics · Physics 2020-06-17 Changhee Lee , Mihaela van der Schaar

High-throughput sequencing can detect tens of thousands of genes in parallel, providing opportunities for improving the diagnostic accuracy of multiple diseases including sepsis, which is an aggressive inflammatory response to infection…

Genomics · Quantitative Biology 2021-12-09 Yueran Yang , Yu Zhang , Shuai Li , Xubin Zheng , Man-Hon Wong , Kwong-Sak Leung , Lixin Cheng

The increase in availability of longitudinal electronic health record (EHR) data is leading to improved understanding of diseases and discovery of novel phenotypes. The majority of clustering algorithms focus only on patient trajectories,…

Machine Learning · Computer Science 2021-11-12 Oliver Carr , Avelino Javer , Patrick Rockenschaub , Owen Parsons , Robert Dürichen

Long-term monitoring of patients with epilepsy presents a challenging problem from the engineering perspective of real-time detection and wearable devices design. It requires new solutions that allow continuous unobstructed monitoring and…

Machine Learning · Computer Science 2022-04-11 Una Pale , Tomas Teijeiro , David Atienza

Although recent studies have proposed seizure detection algorithms with good sensitivity performance, there is a remained challenge that they were hard to achieve significantly short detection latency in real-time scenarios. In this…

Signal Processing · Electrical Eng. & Systems 2023-06-29 Yankun Xu , Jie Yang , Wenjie Ming , Shuang Wang , Mohamad Sawan

Sepsis is a life-threatening disease with high morbidity, mortality and healthcare costs. The early prediction and administration of antibiotics and intravenous fluids is considered crucial for the treatment of sepsis and can save…

Computation and Language · Computer Science 2021-07-26 Fred Qin , Vivek Madan , Ujjwal Ratan , Zohar Karnin , Vishaal Kapoor , Parminder Bhatia , Taha Kass-Hout

Sepsis is a life-threatening medical emergency, which is a major cause of death worldwide and the second highest cause of mortality in the United States. Researching the optimal control treatment or intervention strategy on the…

Dynamical Systems · Mathematics 2022-01-11 Yuyang Chen , Kaiming Bi , Chih-Hang J. Wu , David Ben-Arieh , Ashesh Sinha

In this work, we study the problem pertaining to personalized classification of subclinical atherosclerosis by developing a hierarchical graph neural network framework to leverage two characteristic modalities of a patient: clinical…

Machine Learning · Computer Science 2025-09-15 Irsyad Adam , Steven Swee , Erika Yilin , Ethan Ji , William Speier , Dean Wang , Alex Bui , Wei Wang , Karol Watson , Peipei Ping

Epilepsy is the second most common brain disorder after migraine. Automatic detection of epileptic seizures can considerably improve the patients' quality of life. Current Electroencephalogram (EEG)-based seizure detection systems encounter…

Signal Processing · Electrical Eng. & Systems 2018-03-28 Ramy Hussein , Hamid Palangi , Rabab Ward , Z. Jane Wang

Non-negative tensor factorization has been shown a practical solution to automatically discover phenotypes from the electronic health records (EHR) with minimal human supervision. Such methods generally require an input tensor describing…

Machine Learning · Computer Science 2020-11-13 Kejing Yin , William K. Cheung , Benjamin C. M. Fung , Jonathan Poon

Epilepsy affects 50 million people worldwide and is one of the most common serious neurological disorders. Seizure detection and classification is a valuable tool for diagnosing and maintaining the condition. An automated classification…

Signal Processing · Electrical Eng. & Systems 2022-08-22 Scot Davidson , Niamh McCallan , Kok Yew Ng , Pardis Biglarbeigi , Dewar Finlay , Boon Leong Lan , James McLaughlin

Classification of seizure type is a key step in the clinical process for evaluating an individual who presents with seizures. It determines the course of clinical diagnosis and treatment, and its impact stretches beyond the clinical domain…

Signal Processing · Electrical Eng. & Systems 2024-03-06 David Ahmedt-Aristizabal , Tharindu Fernando , Simon Denman , Lars Petersson , Matthew J. Aburn , Clinton Fookes

We introduce an entropy-based classification method for pairs of sequences (ECPS) for quantifying mutual dependencies in heart rate and beat-to-beat blood pressure recordings. The purpose of the method is to build a classifier for data in…

Fetal heart rate (FHR) monitoring, before and during labor, is a very important medical practice in the detection of fetuses in danger. We clustered FHR tracings by compression in order to identify abnormal ones. We use a recently…

Tissues and Organs · Quantitative Biology 2007-05-23 C. Costa Santos , J. Bernardes , P. Vitanyi , L. Antunes

Modeling patient disease progression using Electronic Health Records (EHRs) is critical to assist clinical decision making. While most of prior work has mainly focused on developing effective disease progression models using EHRs collected…

Machine Learning · Computer Science 2021-03-23 Farzaneh Khoshnevisan , Min Chi
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