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Related papers: Soft Phenotyping for Sepsis via EHR Time-aware Sof…

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Sepsis remains one of the leading causes of mortality in intensive care units, where timely and accurate treatment decisions can significantly impact patient outcomes. In this work, we propose an interpretable decision support framework.…

Machine Learning · Computer Science 2026-01-21 Punit Kumar , Vaibhav Saran , Divyesh Patel , Nitin Kulkarni , Alina Vereshchaka

Sepsis is a major public health concern due to its high morbidity, mortality, and cost. Its clinical outcome can be substantially improved through early detection and timely intervention. By leveraging publicly available datasets, machine…

Machine Learning · Computer Science 2026-02-04 Yin Jin , Tucker R. Stewart , Deyi Zhou , Chhavi Gupta , Arjita Nema , Scott C. Brakenridge , Grant E. O'Keefe , Juhua Hu

Sepsis accounts for nearly 20% of global ICU admissions, yet conventional prediction models often fail to effectively integrate heterogeneous data streams, remaining either siloed by modality or reliant on brittle early fusion. In this…

Machine Learning · Computer Science 2025-12-18 Ryan Cartularo

Sepsis is a leading cause of death in the Intensive Care Units (ICU). Early detection of sepsis is critical for patient survival. In this paper, we propose a multimodal Transformer model for early sepsis prediction, using the physiological…

Machine Learning · Computer Science 2022-03-29 Yuqing Wang , Yun Zhao , Rachael Callcut , Linda Petzold

Apnea-bradycardia is one of the major clinical early indicators of late-onset sepsis occurring in approximately 7% to 10% of all neonates and in more than 25% of very low birth weight infants in NICU. The objective of this paper was to…

Quantitative Methods · Quantitative Biology 2016-05-18 Yuan Wang , Guy Carrault , Alain Beuchee , Nathalie Costet , Huazhong Shu , Lotfi Senhadji

We develop and analyze explainable machine learning (ML) models for sepsis outcome prediction using a novel Electronic Health Record (EHR) dataset from 12,286 hospitalizations at a large emergency hospital in Romania. The dataset includes…

Machine Learning · Computer Science 2026-04-07 Andrei-Alexandru Bunea , Ovidiu Ghibea , Dan-Matei Popovici , Ion Daniel , Octavian Andronic

Although timely sepsis diagnosis and prompt interventions in Intensive Care Unit (ICU) patients are associated with reduced mortality, early clinical recognition is frequently impeded by non-specific signs of infection and failure to detect…

Machine Learning · Computer Science 2018-06-28 Tony Wang , Tom Velez , Emilia Apostolova , Tim Tschampel , Thuy L. Ngo , Joy Hardison

Sepsis is a severe medical condition caused by a dysregulated host response to infection that has a high incidence and mortality rate. Even with such a high-level occurrence rate, the detection and diagnosis of sepsis continues to pose a…

Applications · Statistics 2022-10-27 Jeffrey R. Smith , Yao Xie , Christopher S. Josef , Rishikesan Kamaleswaran

Sepsis and septic shock are a critical medical condition affecting millions globally, with a substantial mortality rate. This paper uses state-of-the-art deep learning (DL) architectures to introduce a multi-step forecasting system to…

Machine Learning · Computer Science 2023-11-09 Anubhav Bhatti , Yuwei Liu , Chen Dan , Bingjie Shen , San Lee , Yonghwan Kim , Jang Yong Kim

Deep learning models have recently shown great success in classifying epileptic patients using EEG recordings. Unfortunately, classification-based methods lack a sound mechanism to detect the onset of seizure events. In this work, we…

Machine Learning · Computer Science 2025-03-04 Zheng Chen , Yasuko Matsubara , Yasushi Sakurai , Jimeng Sun

Early Time Series Classification (ETSC) is critical in time-sensitive medical applications such as sepsis, yet it presents an inherent trade-off between accuracy and earliness. This trade-off arises from two core challenges: 1) models…

Machine Learning · Computer Science 2025-11-06 Tao Xie , Zexi Tan , Haoyi Xiao , Binbin Sun , Yiqun Zhang

Severe sepsis and septic shock are conditions that affect millions of patients and have close to 50% mortality rate. Early identification of at-risk patients significantly improves outcomes. Electronic surveillance tools have been developed…

Computers and Society · Computer Science 2018-09-12 Emilia Apostolova , Tom Velez

Sepsis is a life-threatening condition which requires rapid diagnosis and treatment. Traditional microbiological methods are time-consuming and expensive. In response to these challenges, deep learning algorithms were developed to identify…

Objective: Syncope is a sudden loss of consciousness with loss of postural tone and spontaneous recovery; it is a common condition, albeit one that is challenging to accurately diagnose. Uncertainties about the triggering mechanisms and…

Quantitative Methods · Quantitative Biology 2016-09-08 Joseph Hart , Jesper Mehlsen , Christian H. Olsen , Mette Sofie Olufsen , Pierre Gremaud

Leveraging machine learning techniques for Sepsis early detection and diagnosis has attracted increasing interest in recent years. However, most existing methods require a large amount of labeled training data, which may not be available…

Machine Learning · Computer Science 2023-03-07 Ruiqing Ding , Yu Zhou , Jie Xu , Yan Xie , Qiqiang Liang , He Ren , Yixuan Wang , Yanlin Chen , Leye Wang , Man Huang

With sepsis remaining a leading cause of mortality, early identification of patients with sepsis and those at high risk of death is a challenge of high socioeconomic importance. Given the potential of hyperspectral imaging (HSI) to monitor…

In recent years, healthcare professionals are increasingly emphasizing on personalized and evidence-based patient care through the exploration of prognostic pathways. To study this, structured clinical variables from Electronic Health…

Computation and Language · Computer Science 2025-09-16 Sudeshna Jana , Tirthankar Dasgupta , Lipika Dey

Early and accurate prediction of sepsis onset remains a major challenge in intensive care, where timely detection and subsequent intervention can significantly improve patient outcomes. While machine learning models have shown promise in…

Machine Learning · Computer Science 2025-09-26 Christoph Düsing , Philipp Cimiano

In electronic health records (EHR) analysis, clustering patients according to patterns in their data is crucial for uncovering new subtypes of diseases. Existing medical literature often relies on classical hypothesis testing methods to…

Methodology · Statistics 2024-05-07 Zihan Zhu , Xin Gai , Anru R. Zhang

Heart failure (HF) is a major cause of mortality. Accurately monitoring HF progress and adjust therapies are critical for improving patient outcomes. An experienced cardiologist can make accurate HF stage diagnoses based on combination of…

Machine Learning · Computer Science 2021-03-23 Shuyu Lu , Ruoyu Chen , Wei Wei , Xinghua Lu