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Related papers: Soft Phenotyping for Sepsis via EHR Time-aware Sof…

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Current machine learning models aiming to predict sepsis from Electronic Health Records (EHR) do not account for the heterogeneity of the condition, despite its emerging importance in prognosis and treatment. This work demonstrates the…

Quantitative Methods · Quantitative Biology 2020-11-24 Zina Ibrahim , Honghan Wu , Ahmed Hamoud , Lukas Stappen , Richard Dobson , Andrea Agarossi

Sepsis, characterized by a dysregulated immune response to infection, results in significant mortality, morbidity, and healthcare costs. The timely prediction of sepsis progression is crucial for reducing adverse outcomes through early…

Machine Learning · Computer Science 2026-01-01 Alireza Rafiei , Farshid Hajati , Alireza Rezaee , Amirhossien Panahi , Shahadat Uddin

Electronic Health Records (EHRs) provide high-dimensional temporal data essential for patient modeling; however, conventional algorithmic approaches often rely on data aggregation or imputation, which distorts temporal disease trajectories.…

Machine Learning · Computer Science 2026-04-21 Pi-Ju Tsai , Charkkri Limbud , Kuan-Fu Chen , Yi-Ju Tseng

The timeliness of detection of a sepsis event in progress is a crucial factor in the outcome for the patient. Machine learning models built from data in electronic health records can be used as an effective tool for improving this…

Sepsis is a life-threatening organ malfunction caused by the host's inability to fight infection, which can lead to death without proper and immediate treatment. Therefore, early diagnosis and medical treatment of sepsis in critically ill…

Machine Learning · Computer Science 2023-04-14 Kevin Ewig , Xiangwen Lin , Tucker Stewart , Katherine Stern , Grant O'Keefe , Ankur Teredesai , Juhua Hu

Sepsis is a condition caused by the body's overwhelming and life-threatening response to infection, which can lead to tissue damage, organ failure, and finally death. Common signs and symptoms include fever, increased heart rate, increased…

Machine Learning · Computer Science 2017-09-07 Eitam Sheetrit , Nir Nissim , Denis Klimov , Lior Fuchs , Yuval Elovici , Yuval Shahar

Sepsis is an organ dysfunction caused by a deregulated immune response to an infection. Early sepsis prediction and identification allow for timely intervention, leading to improved clinical outcomes. Clinical calculators (e.g., the…

Machine Learning · Computer Science 2025-01-13 Changchang Yin , Shihan Fu , Bingsheng Yao , Thai-Hoang Pham , Weidan Cao , Dakuo Wang , Jeffrey Caterino , Ping Zhang

Initial hours of hospital admission impact clinical trajectory, but early clinical decisions often suffer due to data paucity. With clustering analysis for vital signs within six hours of admission, patient phenotypes with distinct…

There are significant regional inequities in health resources around the world. It has become one of the most focused topics to improve health services for data-scarce hospitals and promote health equity through knowledge sharing among…

Machine Learning · Computer Science 2023-03-07 Ruiqing Ding , Fangjie Rong , Xiao Han , Leye Wang

Sepsis is a life threatening medical condition that occurs when the body has an extreme response to infection, leading to widespread inflammation, organ failure, and potentially death. Because sepsis can worsen rapidly, early detection is…

Machine Learning · Computer Science 2025-05-07 Oyindolapo O. Komolafe , Zhimin Mei , David Morales Zarate , Gregory William Spangenberg

Sepsis-induced acute respiratory failure (ARF) is a serious complication with a poor prognosis. This paper presents a deep representation learningbased phenotyping method to identify distinct groups of clinical trajectories of septic…

Signal Processing · Electrical Eng. & Systems 2024-05-07 Alan Wu , Tilendra Choudhary , Pulakesh Upadhyaya , Ayman Ali , Philip Yang , Rishikesan Kamaleswaran

Sepsis is a life-threatening host response to infection associated with high mortality, morbidity, and health costs. Its management is highly time-sensitive since each hour of delayed treatment increases mortality due to irreversible organ…

Machine Learning · Computer Science 2020-10-16 Michael Moor , Max Horn , Bastian Rieck , Damian Roqueiro , Karsten Borgwardt

Sepsis is a life-threatening condition that seriously endangers millions of people over the world. Hopefully, with the widespread availability of electronic health records (EHR), predictive models that can effectively deal with clinical…

Machine Learning · Computer Science 2019-10-16 Luchen Liu , Haoxian Wu , Zichang Wang , Zequn Liu , Ming Zhang

Sepsis remains one of the most complex and heterogeneous syndromes in intensive care, characterized by diverse physiological trajectories and variable responses to treatment. While deep learning models perform well in the early prediction…

Machine Learning · Computer Science 2026-04-01 Vincent Lemaire , Nédra Meloulli , Pierre Jaquet

Employing a machine learning approach we predict, up to 24 hours prior, a diagnosis of severe sepsis. Strongly predictive models are possible that use only text reports from the Electronic Health Record (EHR), and omit structured numerical…

Computers and Society · Computer Science 2017-12-01 Phil Culliton , Michael Levinson , Alice Ehresman , Joshua Wherry , Jay S. Steingrub , Stephen I. Gallant

Sepsis is a deadly condition affecting many patients in the hospital. Recent studies have shown that patients diagnosed with sepsis have significant mortality and morbidity, resulting from the body's dysfunctional host response to…

Machine Learning · Computer Science 2022-12-14 Ronald Moore , Rishikesan Kamaleswaran

Interest in an electronic health record-based computational model that can accurately predict a patient's risk of sepsis at a given point in time has grown rapidly in the last several years. Like other EHR vendors, the Epic Systems…

Sepsis is a life-threatening condition caused by a dysregulated host response to infection. Recently, researchers have hypothesized that sepsis consists of a heterogeneous spectrum of distinct subtypes, motivating several studies to…

Applications · Statistics 2025-02-12 Alexander Dombowsky , David B. Dunson , Deng B. Madut , Matthew P. Rubach , Amy H. Herring

Sepsis is an important cause of mortality, especially in intensive care unit (ICU) patients. Developing novel methods to identify early mortality is critical for improving survival outcomes in sepsis patients. Using the MIMIC-III database,…

Computers and Society · Computer Science 2021-12-03 Jiyoung Shin , Yikuan Li , Yuan Luo

Sepsis is a life-threatening and serious global health issue. This study combines knowledge with available hospital data to investigate the potential causes of Sepsis that can be affected by policy decisions. We investigate the underlying…

Machine Learning · Computer Science 2025-02-19 Bruno Petrungaro , Neville K. Kitson , Anthony C. Constantinou
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