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DNA storage has matured from concept to practical stage, yet its integration with neural compression pipelines remains inefficient. Early DNA encoders applied redundancy-heavy constraint layers atop raw binary data - workable but primitive.…

Machine Learning · Computer Science 2026-02-09 Cihan Ruan , Lebin Zhou , Rongduo Han , Linyi Han , Bingqing Zhao , Chenchen Zhu , Wei Jiang , Wei Wang , Nam Ling

Encoding information in combinations of pre-synthesised deoxyribonucleic acid (DNA) strands (referred to as motifs) is an interesting approach to DNA storage that could potentially circumvent the prohibitive costs of…

Information Theory · Computer Science 2024-12-05 Roman Sokolovskii , Parv Agarwal , Luis Alberto Croquevielle , Zijian Zhou , Thomas Heinis

We consider the problem of coding for the substring channel, in which information strings are observed only through their (multisets of) substrings. Due to existing DNA sequencing techniques and applications in DNA-based storage systems,…

Information Theory · Computer Science 2024-03-27 Yonatan Yehezkeally , Nikita Polyanskii

Storing big data directly on a blockchain poses a substantial burden due to the need to maintain a consistent ledger across all nodes. Numerous studies in decentralized storage systems have been conducted to tackle this particular…

Cryptography and Security · Computer Science 2024-10-01 Narges Dadkhah , Xuyang Ma , Katinka Wolter , Gerhard Wunder

We initiate the study of DNA-based distributed storage systems, where information is encoded across multiple DNA data storage containers to achieve robustness against container failures. In this setting, data are distributed over $M$…

Information Theory · Computer Science 2026-02-10 Adi Levy , Roni Con , Eitan Yaakobi , Han Mao Kiah

Distributed storage systems often introduce redundancy to increase reliability. When coding is used, the repair problem arises: if a node storing encoded information fails, in order to maintain the same level of reliability we need to…

Information Theory · Computer Science 2010-04-27 Alexandros G. Dimakis , Kannan Ramchandran , Yunnan Wu , Changho Suh

DNA is a promising medium for digital information storage for its exceptional density and durability. While prior studies advanced coding theory, workflow design, and simulation tools, challenges such as synthesis costs, sequencing errors,…

Emerging Technologies · Computer Science 2025-10-06 Rakesh Thakur , Lavanya Singh , Yashika , Manomay Bundawala , Aruna Kumar

With the advancement in technology, digital images can easily be transmitted and stored over the Internet. Encryption is used to avoid illegal interception of digital images. Encrypting large-sized colour images in their original dimension…

This study explores the self-synchronization problem in DNA coding, specifically addressing single-deletion errors without using delimiters between codewords. We aim to identify the beginning of each codeword without using delimiters,…

Information Theory · Computer Science 2026-03-31 Whan-Hyuk Choi

From currency to cloud storage systems, the continuous rise of the blockchain technology is moving various information systems towards decentralization. Blockchain-based decentralized storage networks (DSNs) offer significantly higher…

Information Theory · Computer Science 2020-05-19 Siyi Yang , Ahmed Hareedy , Robert Calderbank , Lara Dolecek

Digital information can be encoded in the building-block sequence of macromolecules, such as RNA and single-stranded DNA. Methods of "writing" and "reading" macromolecular strands are currently available, but they are slow and expensive. In…

Emerging Technologies · Computer Science 2017-09-14 Pramod K. Khulbe , Raphael Gruener , Masud Mansuripur

In this paper, we introduce DICOD, a convolutional sparse coding algorithm which builds shift invariant representations for long signals. This algorithm is designed to run in a distributed setting, with local message passing, making it…

Machine Learning · Computer Science 2018-05-15 Thomas Moreau , Laurent Oudre , Nicolas Vayatis

Network codes designed specifically for distributed storage systems have the potential to provide dramatically higher storage efficiency for the same availability. One main challenge in the design of such codes is the exact repair problem:…

Information Theory · Computer Science 2011-09-02 Dimitris S. Papailiopoulos , Jianqiang Luo , Alexandros G. Dimakis , Cheng Huang , Jin Li

The vast parallelism, exceptional energy efficiency and extraordinary information inherent in DNA molecules are being explored for computing, data storage and cryptography. DNA cryptography is a emerging field of cryptography. In this paper…

Cryptography and Security · Computer Science 2011-01-14 D. Prabhu , M. Adimoolam

Information Centric Networks (ICNs) have emerged in recent years as a new networking paradigm for the next-generation Internet. The primary goal of these networks is to provide effective mechanisms for content distribution and retrieval…

Networking and Internet Architecture · Computer Science 2020-06-05 Basheer Al-Duwairi , Oznur Ozkasap , Ahmet Uysal , Ceren Kocaogullar , Kaan Yildirim

Motivation: Next Generation Sequencing technologies revolutionized many fields in biology by enabling the fast and cheap sequencing of large amounts of genomic data. The ever increasing sequencing capacities enabled by current sequencing…

Genomics · Quantitative Biology 2012-07-24 Himanshu Asnani , Dinesh Bharadia , Mainak Chowdhury , Idoia Ochoa , Itai Sharon , Tsachy Weissman

A distributed storage system (DSS) needs to be efficiently accessible and repairable. Recently, considerable effort has been made towards the latter, while the former is usually not considered, since a trivial solution exists in the form of…

Information Theory · Computer Science 2020-01-16 Lukas Holzbaur , Stanislav Kruglik , Alexey Frolov , Antonia Wachter-Zeh

We live in a period where bio-informatics is rapidly expanding, a significant quantity of genomic data has been produced as a result of the advancement of high-throughput genome sequencing technology, raising concerns about the costs…

Quantitative Methods · Quantitative Biology 2023-03-10 Mehedi Hasan Sarkar , Adnan Ferdous Ashrafi

A simple DNA-based data storage scheme is demonstrated in which information is written using "addressing" oligonucleotides. In contrast to other methods that allow arbitrary code to be stored, the resulting DNA is suitable for downstream…

Emerging Technologies · Computer Science 2017-11-15 Gary M. Skinner , Koen Visscher , Masud Mansuripur

Deoxyribonucleic Acid (DNA), with its high density and long durability, is a promising storage medium for long-term archival storage and has attracted much attention. Several studies have verified the feasibility of using DNA for archival…

Emerging Technologies · Computer Science 2022-09-15 Yixun Wei , Bingzhe Li , David H. C. Du