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The errors occurring in DNA-based storage are correlated in nature, which is a direct consequence of the synthesis and sequencing processes. In this paper, we consider the memory-$k$ nanopore channel model recently introduced by Hamoum et…

Information Theory · Computer Science 2023-03-27 Issam Maarouf , Eirik Rosnes , Alexandre Graell i Amat

We consider the problem of assembling a sequence based on a collection of its substrings observed through a noisy channel. The mathematical basis of the problem is the construction and design of sequences that may be discriminated based on…

Information Theory · Computer Science 2015-11-04 Han Mao Kiah , Gregory J. Puleo , Olgica Milenkovic

In this paper, we propose an efficient reliability based segmentation-discarding decoding (SDD) algorithm for short block-length codes. A novel segmentation-discarding technique is proposed along with the stopping rule to significantly…

Information Theory · Computer Science 2019-01-23 Chentao Yue , Mahyar Shirvanimoghaddam , Yonghui Li , Branka Vucetic

Large pools of synthetic DNA molecules have been recently used to reliably store significant volumes of digital data. While DNA as a storage medium has enormous potential because of its high storage density, its practical use is currently…

Data Structures and Algorithms · Computer Science 2021-02-25 Konstantin Makarychev , Miklos Z. Racz , Cyrus Rashtchian , Sergey Yekhanin

This article introduces a new DNA sequence compression algorithm which is based on LUT and LZ77 algorithm. Combined a LUT-based pre-coding routine and LZ77 compression routine,this algorithm can approach a compression ratio of 1.9bits…

Information Theory · Computer Science 2007-07-16 Sheng Bao , Shi Chen , Zhiqiang Jing , Ran Ren

The exponential growth in data generation and large-scale data analysis creates an unprecedented need for inexpensive, low-latency, and high-density information storage. This need has motivated significant research into multi-level memory…

To equip DNA-based data storage with random-access capabilities, Yazdi et al. (2018) prepended DNA strands with specially chosen address sequences called primers and provided certain design criteria for these primers. We provide explicit…

Information Theory · Computer Science 2019-01-07 Yeow Meng Chee , Han Mao Kiah , Hengjia Wei

DNA has been considered a promising medium for storing digital information. As an essential step in the DNA-based data storage workflow, coding algorithms are responsible to implement functions including bit-to-base transcoding, error…

Emerging Technologies · Computer Science 2023-03-31 Haoling Zhang , Zhaojun Lan , Wenwei Zhang , Xun Xu , Zhi Ping , Yiwei Zhang , Yue Shen

In the wake of the swift evolution of technologies such as the Internet of Things (IoT), the global data landscape undergoes an exponential surge, propelling DNA storage into the spotlight as a prospective medium for contemporary cloud…

Machine Learning · Computer Science 2024-09-20 Wenfeng Wu , Luping Xiang , Qiang Liu , Kun Yang

DNA labeling is a powerful tool in molecular biology and biotechnology that allows for the visualization, detection, and study of DNA at the molecular level. Under this paradigm, a DNA molecule is being labeled by specific k patterns and is…

Information Theory · Computer Science 2024-01-24 Dganit Hanania , Daniella Bar-Lev , Yevgeni Nogin , Yoav Shechtman , Eitan Yaakobi

We investigate the fundamental limits of the recently proposed random access coverage depth problem for DNA data storage. Under this paradigm, it is assumed that the user information consists of $k$ information strands, which are encoded…

Information Theory · Computer Science 2025-09-25 Anina Gruica , Daniella Bar-Lev , Alberto Ravagnani , Eitan Yaakobi

Decoding sequences that stem from multiple transmissions of a codeword over an insertion, deletion, and substitution channel is a critical component of efficient deoxyribonucleic acid (DNA) data storage systems. In this paper, we consider a…

Information Theory · Computer Science 2020-10-30 Andreas Lenz , Issam Maarouf , Lorenz Welter , Antonia Wachter-Zeh , Eirik Rosnes , Alexandre Graell i Amat

In a distributed storage system, code symbols are dispersed across space in nodes or storage units as opposed to time. In settings such as that of a large data center, an important consideration is the efficient repair of a failed node.…

Information Theory · Computer Science 2018-06-13 S. B. Balaji , M. Nikhil Krishnan , Myna Vajha , Vinayak Ramkumar , Birenjith Sasidharan , P. Vijay Kumar

In order to protect intellectual property against untrusted foundry, many logic-locking schemes have been developed. The main idea of logic locking is to insert a key-controlled block into a circuit to make the circuit function incorrectly…

Hardware Architecture · Computer Science 2022-11-04 Jingbo Zhou , Xinmiao Zhang

In the recent years, DNA has emerged as a potentially viable storage technology. DNA synthesis, which refers to the task of writing the data into DNA, is perhaps the most costly part of existing storage systems. Accordingly, this high cost…

Information Theory · Computer Science 2022-04-15 Ohad Elishco , Wasim Huleihel

The problem of differentiating the informational content of coding (exons) and non-coding (introns) regions of a DNA sequence is one of the central problems of genomics. The introns are estimated to be nearly 95% of the DNA and since they…

Computational Engineering, Finance, and Science · Computer Science 2010-10-21 Riyazuddin Mohammed

Since security is one of the most important issues, the evolve of cryptography and cryptographic analysis are considered as the fields of on-going research. The latest development on this field is DNA cryptography. It has emerged after the…

Cryptography and Security · Computer Science 2015-03-17 Beenish Anam , Kazi Sakib , Md. Alamgir Hossain , Keshav Dahal

In this paper, we consider the problem of designing DNA sequences (codewords) for DNA storage systems and DNA computing that are unlikely to fold back onto themselves to form undesirable secondary structures. The paper addresses both the…

Discrete Mathematics · Computer Science 2016-11-17 Olgica Milenkovic , Navin Kashyap

Future beyond-5G and 6G systems demand ultra-reliable, low-latency communication with short blocklengths, motivating the development of universal decoding algorithms. Guessing decoding, which infers the noise or codeword candidate in order…

Information Theory · Computer Science 2025-11-24 Qianfan Wang , Jifan Liang , Peihong Yuan , Ken R. Duffy , Muriel Médard , Xiao Ma

We consider the problem of storing and retrieving information from synthetic DNA media. The mathematical basis of the problem is the construction and design of sequences that may be discriminated based on their collection of substrings…

Information Theory · Computer Science 2015-02-03 Han Mao Kiah , Gregory J. Puleo , Olgica Milenkovic
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