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Mathematical models connect theory with the real world through data, enabling us to interpret, understand, and predict complex phenomena. However, scientific knowledge often extends beyond what can be empirically measured, offering valuable…

Statistical estimation in many contemporary settings involves the acquisition, analysis, and aggregation of datasets from multiple sources, which can have significant differences in character and in value. Due to these variations, the…

Applications · Statistics 2014-12-23 Quentin Berthet , Venkat Chandrasekaran

Causal inference is central to many areas of artificial intelligence, including complex reasoning, planning, knowledge-base construction, robotics, explanation, and fairness. An active community of researchers develops and enhances…

Artificial Intelligence · Computer Science 2019-11-05 Amanda Gentzel , Dan Garant , David Jensen

This chapter provides a overview of Bayesian inference, mostly emphasising that it is a universal method for summarising uncertainty and making estimates and predictions using probability statements conditional on observed data and an…

Methodology · Statistics 2010-02-11 Christian P. Robert , Jean-Michel Marin , Judith Rousseau

The ideas of aleatoric and epistemic uncertainty are widely used to reason about the probabilistic predictions of machine-learning models. We identify incoherence in existing discussions of these ideas and suggest this stems from the…

Machine Learning · Computer Science 2025-08-19 Freddie Bickford Smith , Jannik Kossen , Eleanor Trollope , Mark van der Wilk , Adam Foster , Tom Rainforth

A great deal of effort has been devoted to reducing the risk of spurious scientific discoveries, from the use of sophisticated validation techniques, to deep statistical methods for controlling the false discovery rate in multiple…

Machine Learning · Computer Science 2016-03-03 Cynthia Dwork , Vitaly Feldman , Moritz Hardt , Toniann Pitassi , Omer Reingold , Aaron Roth

We study statistical inference and distributionally robust solution methods for stochastic optimization problems, focusing on confidence intervals for optimal values and solutions that achieve exact coverage asymptotically. We develop a…

Machine Learning · Statistics 2018-07-03 John Duchi , Peter Glynn , Hongseok Namkoong

Practical problems with missing data are common, and statistical methods have been developed concerning the validity and/or efficiency of statistical procedures. On a central focus, there have been longstanding interests on the mechanism…

Methodology · Statistics 2020-03-26 Rui Duan , C. Jason Liang , Pamela Shaw , Cheng Yong Tang , Yong Chen

The last decades saw dramatic progress in brain research. These advances were often buttressed by probing single variables to make circumscribed discoveries, typically through null hypothesis significance testing. New ways for generating…

Neurons and Cognition · Quantitative Biology 2019-03-26 Danilo Bzdok , John Ioannidis

There are various approaches to the problem of how one is supposed to conduct a statistical analysis. Different analyses can lead to contradictory conclusions in some problems so this is not a satisfactory state of affairs. It seems that…

Statistics Theory · Mathematics 2019-06-25 Michael Evans

For many interesting tasks, such as medical diagnosis and web page classification, a learner only has access to some positively labeled examples and many unlabeled examples. Learning from this type of data requires making assumptions about…

Machine Learning · Computer Science 2018-08-28 Jessa Bekker , Jesse Davis

Ensuring that analyses performed on a dataset are representative of the entire population is one of the central problems in statistics. Most classical techniques assume that the dataset is independent of the analyst's query and break down…

Machine Learning · Computer Science 2024-09-25 Guy Blanc

Topological models of empirical and formal inquiry are increasingly prevalent. They have emerged in such diverse fields as domain theory [1, 16], formal learning theory [18], epistemology and philosophy of science [10, 15, 8, 9, 2],…

Machine Learning · Computer Science 2017-08-01 Konstantin Genin , Kevin T. Kelly

Machine learning theory has mostly focused on generalization to samples from the same distribution as the training data. Whereas a better understanding of generalization beyond the training distribution where the observed distribution…

Machine Learning · Statistics 2019-05-29 Matias Vera , Pablo Piantanida , Leonardo Rey Vega

Empirical process theory for i.i.d. observations has emerged as a ubiquitous tool for understanding the generalization properties of various statistical problems. However, in many applications where the data exhibit temporal dependencies…

Statistics Theory · Mathematics 2024-01-18 Nabarun Deb , Debarghya Mukherjee

Statistically sound pattern discovery harnesses the rigour of statistical hypothesis testing to overcome many of the issues that have hampered standard data mining approaches to pattern discovery. Most importantly, application of…

Methodology · Statistics 2019-01-07 Wilhelmiina Hämäläinen , Geoffrey I. Webb

Statistical hypothesis testing, as formalized by 20th Century statisticians and taught in college statistics courses, has been a cornerstone of 100 years of scientific progress. Nevertheless, the methodology is increasingly questioned in…

Methodology · Statistics 2024-08-22 Brian Dennis , Mark L Taper , José M Ponciano

For obtaining causal inferences that are objective, and therefore have the best chance of revealing scientific truths, carefully designed and executed randomized experiments are generally considered to be the gold standard. Observational…

Applications · Statistics 2008-11-12 Donald B. Rubin

As the frontiers of applied statistics progress through increasingly complex experiments we must exploit increasingly sophisticated inferential models to analyze the observations we make. In order to avoid misleading or outright erroneous…

Methodology · Statistics 2018-03-23 Michael Betancourt

Prediction, where observed data is used to quantify uncertainty about a future observation, is a fundamental problem in statistics. Prediction sets with coverage probability guarantees are a common solution, but these do not provide…

Statistics Theory · Mathematics 2022-11-22 Leonardo Cella , Ryan Martin