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Segment Anything Model (SAM) is one of the pioneering prompt-based foundation models for image segmentation and has been rapidly adopted for various medical imaging applications. However, in clinical settings, creating effective prompts is…

Computer Vision and Pattern Recognition · Computer Science 2024-11-26 Chengyin Li , Prashant Khanduri , Yao Qiang , Rafi Ibn Sultan , Indrin Chetty , Dongxiao Zhu

Purpose: To evaluate various Segmental Anything Model (SAM) prompt strategies across four lesions datasets and to subsequently develop a reinforcement learning (RL) agent to optimize SAM prompt placement. Materials and Methods: This…

Image and Video Processing · Electrical Eng. & Systems 2024-12-31 Yuli Wang , Victoria Shi , Wen-Chi Hsu , Yuwei Dai , Sophie Yao , Zhusi Zhong , Zishu Zhang , Jing Wu , Aaron Maxwell , Scott Collins , Zhicheng Jiao , Harrison X. Bai

Medical image segmentation is vital to the area of medical imaging because it enables professionals to more accurately examine and understand the information offered by different imaging modalities. The technique of splitting a medical…

Image and Video Processing · Electrical Eng. & Systems 2024-09-01 Aitik Gupta , Joydip Dhar

The remarkable capabilities of the Segment Anything Model (SAM) for tackling image segmentation tasks in an intuitive and interactive manner has sparked interest in the design of effective visual prompts. Such interest has led to the…

Computer Vision and Pattern Recognition · Computer Science 2024-11-01 Jorge Quesada , Zoe Fowler , Mohammad Alotaibi , Mohit Prabhushankar , Ghassan AlRegib

Automated segmentation of cancer on medical images can aid targeted diagnostic and therapeutic procedures. However, its adoption is limited by the high cost of expert annotations required for training and inter-observer variability in…

Image and Video Processing · Electrical Eng. & Systems 2025-05-26 Lynn Karam , Yipei Wang , Veeru Kasivisvanathan , Mirabela Rusu , Yipeng Hu , Shaheer U. Saeed

Interactive segmentation uses real-time user inputs, such as mouse clicks, to iteratively refine model predictions. Although not originally designed to address distribution shifts, this paradigm naturally lends itself to such challenges. In…

Computer Vision and Pattern Recognition · Computer Science 2026-04-22 Wentian Xu , Ziyun Liang , Harry Anthony , Yasin Ibrahim , Felix Cohen , Guang Yang , Konstantinos Kamnitsas

Foundation models such as Segment Anything Model 3 (SAM3) enable flexible text-guided medical image segmentation, yet their predictions remain highly sensitive to prompt formulation. Even semantically equivalent descriptions can yield…

Computer Vision and Pattern Recognition · Computer Science 2026-03-09 Yonghuang Wu , Zhenyang Liang , Wenwen Zeng , Xuan Xie , Jinhua Yu

Manual segmentation of medical images (e.g., segmenting tumors in CT scans) is a high-effort task that can be accelerated with machine learning techniques. However, selecting the right segmentation approach depends on the evaluation…

Computer Vision and Pattern Recognition · Computer Science 2023-02-09 Seyed M. R. Modaresi , Aomar Osmani , Mohammadreza Razzazi , Abdelghani Chibani

Segment Anything Model (SAM) has demonstrated impressive zero-shot performance and brought a range of unexplored capabilities to natural image segmentation tasks. However, as a very important branch of image segmentation, the performance of…

Computer Vision and Pattern Recognition · Computer Science 2025-02-04 Bin Xie , Hao Tang , Dawen Cai , Yan Yan , Gady Agam

Background: In the field of radiology and radiotherapy, accurate delineation of tissues and organs plays a crucial role in both diagnostics and therapeutics. While the gold standard remains expert-driven manual segmentation, many automatic…

Quantitative Methods · Quantitative Biology 2025-08-14 Szuzina Fazekas , Bettina Katalin Budai , Viktor Bérczi , Pál Maurovich-Horvat , Zsolt Vizi

Establishing pixel/voxel-level or region-level correspondences is the core challenge in image registration. The latter, also known as region-based correspondence representation, leverages paired regions of interest (ROIs) to enable regional…

Computer Vision and Pattern Recognition · Computer Science 2025-08-05 Shiqi Huang , Tingfa Xu , Wen Yan , Dean Barratt , Yipeng Hu

To address prevalent issues in medical imaging, such as data acquisition challenges and label availability, transfer learning from natural to medical image domains serves as a viable strategy to produce reliable segmentation results.…

Image and Video Processing · Electrical Eng. & Systems 2023-11-15 Hao Li , Han Liu , Dewei Hu , Jiacheng Wang , Ipek Oguz

This paper proposes a two-stage segmentation model, variable-input based uncertainty measures and an uncertainty-guided post-processing method for prostate segmentation on 3D magnetic resonance images (MRI). The two-stage model was based on…

Computer Vision and Pattern Recognition · Computer Science 2019-03-07 Huitong Pan , Yushan Feng , Quan Chen , Craig Meyer , Xue Feng

Tumor region segmentation is an essential task for the quantitative analysis of digital pathology. Recently presented deep neural networks have shown state-of-the-art performance in various image-segmentation tasks. However, because of the…

Computer Vision and Pattern Recognition · Computer Science 2023-07-04 Seonghui Min , Won-Ki Jeong

The Segment Anything Model (SAM) has recently demonstrated significant potential in medical image segmentation. Although SAM is primarily trained on 2D images, attempts have been made to apply it to 3D medical image segmentation. However,…

Computer Vision and Pattern Recognition · Computer Science 2025-11-25 Fangda Chen , Jintao Tang , Pancheng Wang , Ting Wang , Shasha Li , Ting Deng

Prompt engineering is still the primary way for users of generative text-to-image models to manipulate generated images in a targeted way. Based on treating the model as a continuous function and by passing gradients between the image space…

Computer Vision and Pattern Recognition · Computer Science 2024-06-25 Niklas Deckers , Julia Peters , Martin Potthast

Point-based interactive image segmentation can ease the burden of mask annotation in applications such as semantic segmentation and image editing. However, fully extracting the target mask with limited user inputs remains challenging. We…

Computer Vision and Pattern Recognition · Computer Science 2023-12-25 Chaowei Fang , Ziyin Zhou , Junye Chen , Hanjing Su , Qingyao Wu , Guanbin Li

In this paper, we propose a novel text promptable surgical instrument segmentation approach to overcome challenges associated with diversity and differentiation of surgical instruments in minimally invasive surgeries. We redefine the task…

Computer Vision and Pattern Recognition · Computer Science 2024-06-05 Zijian Zhou , Oluwatosin Alabi , Meng Wei , Tom Vercauteren , Miaojing Shi

Biomedical image segmentation is a crucial part of both scientific research and clinical care. With enough labelled data, deep learning models can be trained to accurately automate specific biomedical image segmentation tasks. However,…

Computer Vision and Pattern Recognition · Computer Science 2024-07-18 Hallee E. Wong , Marianne Rakic , John Guttag , Adrian V. Dalca

Purpose: Endoscopic surgical environments present challenges for dissection zone segmentation due to unclear boundaries between tissue types, leading to segmentation errors where models misidentify or overlook edges. This study aims to…

Computer Vision and Pattern Recognition · Computer Science 2024-11-28 Mengya Xu , Wenjin Mo , Guankun Wang , Huxin Gao , An Wang , Zhen Li , Xiaoxiao Yang , Hongliang Ren