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We present a new explicit local space-time adaptive framework to decrease the time required for monodomain simulations for cardiac electrophysiology. Based on the localized structure of the steep activation wavefront in solutions to…

Numerical Analysis · Mathematics 2025-02-03 Dennis Ogiermann , Daniel Balzani , Luigi E. Perotti

For plane-wave and many-spiral states of the experimentally based Luo-Rudy 1 model of heart tissue in large (8 cm square) domains, we show that an explicit space-time-adaptive time-integration algorithm can achieve an order of magnitude…

Computational Physics · Physics 2009-10-31 Elizabeth M. Cherry , Henry S. Greenside , Craig S. Henriquez

Mathematical models of the human heart are increasingly playing a vital role in understanding the working mechanisms of the heart, both under healthy functioning and during disease. The aim is to aid medical practitioners diagnose and treat…

Numerical Analysis · Mathematics 2023-11-13 Sridhar Chellappa , Barış Cansız , Lihong Feng , Peter Benner , Michael Kaliske

In this work, we investigate the numerical reconstruction of inclusions in a semilinear elliptic equation arising in the mathematical modeling of cardiac ischemia. We propose an adaptive finite element method for the resulting constrained…

Numerical Analysis · Mathematics 2025-08-07 Bangti Jin , Fengru Wang , Yifeng Xu

This work deals with the numerical solution of the monodomain and bidomain models of electrical activity of myocardial tissue. The bidomain model is a system consisting of a possibly degenerate parabolic PDE coupled with an elliptic PDE for…

Numerical Analysis · Mathematics 2008-07-03 Mostafa Bendahmane , Raimund Bürger , Ricardo Ruiz Baier

The spectral deferred correction (SDC) method is an iterative scheme for computing a higher-order collocation solution to an ODE by performing a series of correction sweeps using a low-order timestepping method. This paper examines a…

Numerical Analysis · Mathematics 2015-10-09 Robert Speck , Daniel Ruprecht , Matthew Emmett , Michael Minion , Matthias Bolten , Rolf Krause

The forward problem in electrocardiology, computing body surface potentials from cardiac electrical activity, is traditionally solved using physics-based models such as the bidomain or monodomain equations. While accurate, these approaches…

Image and Video Processing · Electrical Eng. & Systems 2025-12-17 Shaheim Ogbomo-Harmitt , Cesare Magnetti , Chiara Spota , Jakub Grzelak , Oleg Aslanidi

In this paper, we consider the problem of accelerating the numerical simulation of time dependent problems by time domain decomposition. The available algorithms enabling such decompositions present severe efficiency limitations and are an…

Numerical Analysis · Mathematics 2020-03-27 Y. Maday , O. Mula

Models of electrical excitation and recovery in the heart have become increasingly detailed, but have yet to be used routinely in the clinical setting to guide personalized intervention in patients. One of the main challenges is calibrating…

Spectral deferred corrections (SDC) is an iterative approach for constructing higher- order accurate numerical approximations of ordinary differential equations. SDC starts with an initial approximation of the solution defined at a set of…

Computational Engineering, Finance, and Science · Computer Science 2017-06-14 R. W. Grout , H. Kolla , M. L. Minion , J. B. Bell

Stiff hyperbolic balance laws exhibit large spectral gaps, especially if the relaxation term significantly varies in space. Using examples from rarefied gases and the general form of the underlying balance law model, we perform a detailed…

Numerical Analysis · Mathematics 2021-08-31 Julian Koellermeier , Giovanni Samaey

Cardiac parametric mapping is useful for evaluating cardiac fibrosis and edema. Parametric mapping relies on single-shot heartbeat-by-heartbeat imaging, which is susceptible to intra-shot motion during the imaging window. However, reducing…

Image and Video Processing · Electrical Eng. & Systems 2025-03-25 Calder D. Sheagren , Brenden T. Kadota , Jaykumar H. Patel , Mark Chiew , Graham A. Wright

Computer-based simulations of non-invasive cardiac electrical outputs, such as electrocardiograms and body surface potential maps, usually entail severe computational costs due to the need of capturing fine-scale processes and to the…

Numerical Analysis · Mathematics 2023-08-09 Elena Zappon , Andrea Manzoni , Alfio Quarteroni

For the study of complex synthetic and biological molecular systems by computer simulations one is still restricted to simple model systems or to by far too small time scales. To overcome this problem multiscale techniques are being…

Statistical Mechanics · Physics 2007-05-23 Matej Praprotnik , Kurt Kremer , Luigi Delle Site

Constructing approximations that can accurately mimic the behavior of complex models at reduced computational costs is an important aspect of uncertainty quantification. Despite their flexibility and efficiency, classical surrogate models…

Computation · Statistics 2020-06-29 S. Marelli , P. -R. Wagner , C. Lataniotis , B. Sudret

Simulation of the monodomain equation, crucial for modeling the heart's electrical activity, faces scalability limits when traditional numerical methods only parallelize in space. To optimize the use of large multi-processor computers by…

Numerical Analysis · Mathematics 2024-05-31 Giacomo Rosilho de Souza , Simone Pezzuto , Rolf Krause

In this paper, we focus on solving a sequence of linear systems with an identical (or similar) coefficient matrix. For this type of problems, we investigate the subspace correction and deflation methods, which use an auxiliary matrix…

Numerical Analysis · Mathematics 2022-03-17 Takeshi Iwashita , Kota Ikehara , Takeshi Fukaya , Takeshi Mifune

Starting from a recent a posteriori error estimator for the finite element solution of the wave equation with explicit time-stepping [Grote, Lakkis, Santos, 2024], we devise a space-time adaptive strategy which includes both time evolving…

Numerical Analysis · Mathematics 2026-01-07 Marcus J. Grote , Omar Lakkis , Carina S. Santos

In this paper, we demonstrate that the explicit ADER approach as it is used inter alia in [1] can be seen as a special interpretation of the deferred correction (DeC) method as introduced in [2]. By using this fact, we are able to embed…

Numerical Analysis · Mathematics 2022-11-17 Maria Han Veiga , Philipp Öffner , Davide Torlo

This work introduces a time-adaptive strategy that uses a refinement estimator based on the first Frenet curvature. In dynamics, a time-adaptive strategy is a mechanism that interactively proposes changes to the time step used in iterative…

Numerical Analysis · Computer Science 2013-05-30 E. N. Lages , E. S. S. Silveira , D. T. Cintra , A. C. Frery
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