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Parameterizing mathematical models of biological systems often requires fitting to stable periodic data. In cardiac electrophysiology this typically requires converging to a stable action potential through long simulations. We explore this…

Quantitative Methods · Quantitative Biology 2025-01-16 Matt J Owen , Gary R Mirams

The monodomain model is widely used in in-silico cardiology to describe excitation propagation in the myocardium. Frequently, operator splitting is used to decouple the stiff reaction term and the diffusion term in the monodomain model so…

Numerical Analysis · Mathematics 2021-10-14 Konstantinos A Mountris , Esther Pueyo

Implicit time integration is key to robustly simulating stiff materials and large deformations, but its performance is often dominated by repeatedly solving large linear systems. Adaptive coarsening can reduce this cost by concentrating…

Graphics · Computer Science 2026-05-07 Xuan Wang , Zhaofeng Luo , Minchen Li , Taku Komura , Kemeng Huang

We study the evolution of solidification microstructures using a phase-field model computed on an adaptive, finite element grid. We discuss the details of our algorithm and show that it greatly reduces the computational cost of solving the…

Materials Science · Physics 2009-10-31 Nikolas Provatas , Nigel Goldenfeld , Jonathan Dantzig

We review some of the latest approaches to analysing cardiac electrophysiology data using machine learning and predictive modelling. Cardiac arrhythmias, particularly atrial fibrillation, are a major global healthcare challenge. Treatment…

This paper introduces the multiplicative variant of the recently proposed asynchronous additive coarse-space correction method. Definition of an asynchronous extension of multiplicative correction is not straightforward, however, our…

Numerical Analysis · Mathematics 2023-12-20 Guillaume Gbikpi-Benissan , Frédéric Magoulès

Flexibility at hardware level is the main driving force behind adaptive systems whose aim is to realise microarhitecture deconfiguration 'online'. This feature allows the software/hardware stack to tolerate drastic changes of the workload…

Hardware Architecture · Computer Science 2016-12-28 Ana Lava , Mahdi Jelodari Mamaghani , Siamak Mohammadi , Steve Furber

In this work we present two new families of multirate time step adaptivity controllers, that are designed to work with embedded multirate infinitesimal (MRI) time integration methods for adapting time steps when solving problems with…

Numerical Analysis · Mathematics 2026-03-11 Daniel R. Reynolds , Sylvia Amihere , Dashon Mitchell , Vu Thai Luan

We present a fully adaptive multiresolution scheme for spatially two-dimensional, possibly degenerate reaction-diffusion systems, focusing on combustion models and models of pattern formation and chemotaxis in mathematical biology.…

Numerical Analysis · Mathematics 2008-07-10 Mostafa Bendahmane , Raimund Bürger , Ricardo Ruiz Baier , Kai Schneider

Computational models are increasingly used for diagnosis and treatment of cardiovascular disease. To provide a quantitative hemodynamic understanding that can be effectively used in the clinic, it is crucial to quantify the variability in…

Computational Engineering, Finance, and Science · Computer Science 2021-02-02 Xue Li , Daniele E. Schiavazzi

Reliable motion estimation and strain analysis using 3D+time echocardiography (4DE) for localization and characterization of myocardial injury is valuable for early detection and targeted interventions. However, motion estimation is…

We present a new adaptive method for electronic structure calculations based on novel fast algorithms for reduction of multivariate mixtures. In our calculations, spatial orbitals are maintained as Gaussian mixtures whose terms are selected…

Numerical Analysis · Mathematics 2019-06-19 Gregory Beylkin , Lucas Monzon , Xinshuo Yang

We consider a linear symmetric and elliptic PDE and a linear goal functional. We design and analyze a goal-oriented adaptive finite element method, which steers the adaptive mesh-refinement as well as the approximate solution of the arising…

Numerical Analysis · Mathematics 2024-01-12 Roland Becker , Gregor Gantner , Michael Innerberger , Dirk Praetorius

The electrocardiogram (ECG) is a well-known technique used to diagnose cardiac diseases. To acquire the spatial signal characteristics from the thorax, multiple electrodes are commonly used. Displacements of electrodes affect the signal…

Medical Physics · Physics 2021-12-15 Andra Oltmann , Roman Kusche , Philipp Rostalski

A space-time adaptive method is presented for the reactive Euler equations describing chemically reacting gas flow where a two species model is used for the chemistry. The governing equations are discretized with a finite volume method and…

Computational Physics · Physics 2019-12-16 Olivier Roussel , Kai Schneider

We propose a method for automatic local time-adaptation of the spectrogram of audio signals: it is based on the decomposition of a signal within a Gabor multi-frame through the STFT operator. The sparsity of the analysis in every individual…

Sound · Computer Science 2011-09-29 M. Liuni , A. Röbel , M. Romito , X. Rodet

Self-assembly processes in biological and synthetic biomolecular systems are often governed by the spatial separation of biochemical processes. While previous work has focused on optimizing self-assembly through fine-tuned reaction…

Biological Physics · Physics 2026-02-17 Severin Angerpointner , Richard Swiderski , Erwin Frey

This paper investigates an adaptive wavelet collocation time domain method for the numerical solution of Maxwell's equations. In this method a computational grid is dynamically adapted at each time step by using the wavelet decomposition of…

Numerical Analysis · Mathematics 2012-04-06 Haojun Li , Kirankumar R. Hiremath , Andreas Rieder , Wolfgang Freude

Numerical Simulation is an essential part of the design and optimisation of astronomical adaptive optics systems. Simulations of adaptive optics are computationally expensive and the problem scales rapidly with telescope aperture size, as…

Astrophysics · Physics 2009-11-13 A. G. Basden , F. Assemat , T. Butterley , D. Geng , C. D. Saunter , R. W. Wilson

We propose a new paradigm for designing efficient p-adaptive arbitrary high order methods. We consider arbitrary high order iterative schemes that gain one order of accuracy at each iteration and we modify them in order to match the…

Numerical Analysis · Mathematics 2023-11-09 Lorenzo Micalizzi , Davide Torlo , Walter Boscheri