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Geometry optimization is an important task in quantum chemical calculations to analyze the characteristics of molecules. A top concern on it is a long execution time because time-consuming energy and gradient calculations are repeated…

Chemical Physics · Physics 2024-04-22 Satoshi Imamura , Akihiko Kasagi , Eiji Yoshida

We propose a reduced-space formulation for optimizing over trained neural networks where the network's outputs and derivatives are evaluated on a GPU. To do this, we treat the neural network as a "gray box" where intermediate variables and…

Machine Learning · Computer Science 2025-12-10 Robert Parker , Oscar Dowson , Nicole LoGiudice , Manuel Garcia , Russell Bent

Generative adversarial imitation learning (GAIL) demonstrates tremendous success in practice, especially when combined with neural networks. Different from reinforcement learning, GAIL learns both policy and reward function from expert…

Machine Learning · Computer Science 2020-06-26 Yufeng Zhang , Qi Cai , Zhuoran Yang , Zhaoran Wang

In standard generative deep learning models, such as autoencoders or GANs, the size of the parameter set is proportional to the complexity of the generated data distribution. A significant challenge is to deploy resource-hungry deep…

Machine Learning · Computer Science 2021-10-29 Shreshth Tuli , Shikhar Tuli , Giuliano Casale , Nicholas R. Jennings

As the size and ubiquity of artificial intelligence and computational machine learning (ML) models grow, their energy consumption for training and use is rapidly becoming economically and environmentally unsustainable. Neuromorphic…

Disordered Systems and Neural Networks · Physics 2023-10-17 Menachem Stern , Sam Dillavou , Dinesh Jayaraman , Douglas J. Durian , Andrea J. Liu

Gradient-free optimizers allow for tackling problems regardless of the smoothness or differentiability of their objective function, but they require many more iterations to converge when compared to gradient-based algorithms. This has made…

Machine Learning · Computer Science 2024-09-24 Gawel Kus , Miguel A. Bessa

The online optimization of gasoline blending benefits refinery economies. However, the nonlinear blending mechanism, the oil property fluctuations, and the blending model mismatch bring difficulties to the optimization. To solve the above…

Computational Engineering, Finance, and Science · Computer Science 2023-09-07 Muyi Huang , Renchu He , Xin Dai , Xin Peng , Wenli Du , Feng Qian

Solving the optimal power flow (OPF) problem in real-time electricity market improves the efficiency and reliability in the integration of low-carbon energy resources into the power grids. To address the scalability and adaptivity issues of…

Machine Learning · Computer Science 2021-06-22 Shaohui Liu , Chengyang Wu , Hao Zhu

The optimisation of neural networks can be sped up by orthogonalising the gradients before the optimisation step, ensuring the diversification of the learned representations. We orthogonalise the gradients of the layer's components/filters…

Machine Learning · Computer Science 2022-02-16 Mark Tuddenham , Adam Prügel-Bennett , Jonathan Hare

High-fidelity physics simulations are powerful tools in the design and optimization of charged particle accelerators. However, the computational burden of these simulations often limits their use in practice for design optimization and…

Accelerator Physics · Physics 2020-04-15 Auralee Edelen , Nicole Neveu , Yannick Huber , Mattias Frey , Christopher Mayes , Andreas Adelmann

This manuscript proposes an optimization framework to find the tailor-made functionally graded material (FGM) profiles for thermoelastic applications. This optimization framework consists of (1) a random profile generation scheme, (2) deep…

Computational Engineering, Finance, and Science · Computer Science 2024-08-27 Piyush Agrawal , Ihina Mahajan , Shivam Choubey , Manish Agrawal

Black-box algorithms are designed to optimize functions without relying on their underlying analytical structure or gradient information, making them essential when gradients are inaccessible or difficult to compute. Traditional methods for…

Machine Learning · Computer Science 2026-01-21 Yedidya Kfir , Elad Sarafian , Sarit Kraus , Yoram Louzoun

This paper proposes a novel approach to improve the training efficiency and the generalization performance of Feed Forward Neural Networks (FFNNs) resorting to an optimal rescaling of input features (OFR) carried out by a Genetic Algorithm…

Machine Learning · Computer Science 2024-02-21 Federico Maria Vitrò , Marco Leonesio , Lorenzo Fagiano

Deep neural networks (DNNs) depend on the storage of a large number of parameters, which consumes an important portion of the energy used during inference. This paper considers the case where the energy usage of memory elements can be…

Machine Learning · Computer Science 2019-12-24 Sébastien Henwood , François Leduc-Primeau , Yvon Savaria

We propose to optimize neural networks with a uniformly-distributed random learning rate. The associated stochastic gradient descent algorithm can be approximated by continuous stochastic equations and analyzed within the Fokker-Planck…

Machine Learning · Computer Science 2020-10-13 Daniele Musso

Modern machine learning often requires training with large batch size, distributed data, and massively parallel compute hardware (like mobile and other edge devices or distributed data centers). Communication becomes a major bottleneck in…

Machine Learning · Computer Science 2025-12-12 Ahmed Khaled , Satyen Kale , Arthur Douillard , Chi Jin , Rob Fergus , Manzil Zaheer

Graphical models are widely used in science to represent joint probability distributions with an underlying conditional dependence structure. The inverse problem of learning a discrete graphical model given i.i.d samples from its joint…

Machine Learning · Computer Science 2020-12-24 Abhijith J. , Andrey Y. Lokhov , Sidhant Misra , Marc Vuffray

Chemistry Foundation Models (CFMs) that leverage Graph Neural Networks (GNNs) operating on 3D molecular graph structures are becoming indispensable tools for computational chemists and materials scientists. These models facilitate the…

Projected Gradient Descent (PGD) based adversarial training has become one of the most prominent methods for building robust deep neural network models. However, the computational complexity associated with this approach, due to the…

Machine Learning · Computer Science 2020-05-01 Sidharth Gupta , Parijat Dube , Ashish Verma

The structural design of functional molecules, also called molecular optimization, is an essential chemical science and engineering task with important applications, such as drug discovery. Deep generative models and combinatorial…

Machine Learning · Computer Science 2022-01-25 Tianfan Fu , Wenhao Gao , Cao Xiao , Jacob Yasonik , Connor W. Coley , Jimeng Sun
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