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Knee osteoporosis weakens the bone tissue in the knee joint, increasing fracture risk. Early detection through X-ray images enables timely intervention and improved patient outcomes. While some researchers have focused on diagnosing knee…

Radiographic grading of knee osteoarthritis (KOA) with the Kellgren-Lawrence (KL) system is limited by inter-reader variability and the opacity of current deep learning approaches, which predict KL grades directly from images without…

The aim of this study was to investigate the influence of MRI and patient data on the prediction of knee osteoarthritis (OA) incidence using different deep learning architectures. Knee OA incidence within 24 months was predicted using the…

We developed deep learning models for predicting Total Knee Replacement (TKR) need within various time horizons in knee osteoarthritis patients, with a novel capability: the models can perform TKR prediction using a single scan, and…

Knee Osteoarthritis (OA) is a common musculoskeletal disorder in the United States. When diagnosed at early stages, lifestyle interventions such as exercise and weight loss can slow OA progression, but at later stages, only an invasive…

Knee osteoarthritis (OA) is one of the most widespread and burdensome health problems [1-4]. Total knee replacement (TKR) may be offered as treatment for end-stage knee OA. Nevertheless, TKR is an invasive procedure involving prosthesis…

Knee osteoarthritis frequently exhibits discordance between structural damage observed in imaging and patient-reported symptoms such as pain. This mismatch complicates clinical interpretation and patient stratification and remains…

Medical imaging plays a crucial role in assessing knee osteoarthritis (OA) risk by enabling early detection and disease monitoring. Recent machine learning methods have improved risk estimation (i.e., predicting the likelihood of disease…

Conventional inclusion criteria used in osteoarthritis clinical trials are not very effective in selecting patients who would benefit from a therapy being tested. Typically majority of selected patients show no or limited disease…

Introduction: Bone health disorders like osteoarthritis and osteoporosis pose major global health challenges, often leading to delayed diagnoses due to limited diagnostic tools. This study presents an AI-powered system that analyzes knee…

Conventional fine-tuning on domain-specific datasets can inadvertently alter a model's pretrained multimodal priors, leading to reduced generalization. To address this, we propose Chain-of-Adaptation (CoA), an adaptation framework designed…

We present a fully automated learning-based approach for segmenting knee cartilage in the presence of osteoarthritis (OA). The algorithm employs a hierarchical set of two random forest classifiers. The first is a neighborhood approximation…

Degeneration of articular cartilage (AC) is actively studied in knee osteoarthritis (OA) research via magnetic resonance imaging (MRI). Segmentation of AC tissues from MRI data is an essential step in quantification of their damage. Deep…

Knee osteoarthritis (OA) is very common progressive and degenerative musculoskeletal disease worldwide creates a heavy burden on patients with reduced quality of life and also on society due to financial impact. Therefore, any attempt to…

This work proposes a novel end-to-end convolutional neural network (CNN) architecture to automatically quantify the severity of knee osteoarthritis (OA) using X-Ray images, which incorporates trainable attention modules acting as…

Knee osteoarthritis (KOA) is a prevalent musculoskeletal disorder, often diagnosed using X-rays due to its cost-effectiveness. While Magnetic Resonance Imaging (MRI) provides superior soft tissue visualization and serves as a valuable…

Knee Osteoarthritis (OA) is a debilitating disease affecting over 250 million people worldwide. Currently, radiologists grade the severity of OA on an ordinal scale from zero to four using the Kellgren-Lawrence (KL) system. Recent studies…

Knee osteoarthritis (OA) is a major cause of disability worldwide and is still largely assessed using subjective radiographic grading, most commonly the Kellgren-Lawrence (KL) scale. Artificial intelligence (AI) and radiomics offer…

A fully automated knee MRI segmentation method to study osteoarthritis (OA) was developed using a novel hierarchical set of random forests (RF) classifiers to learn the appearance of cartilage regions and their boundaries. A neighborhood…

A fully-automated deep learning algorithm matched performance of radiologists in assessment of knee osteoarthritis severity in radiographs using the Kellgren-Lawrence grading system. To develop an automated deep learning-based algorithm…