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Knee osteoarthritis (OA) is the most common joint disorder and a leading cause of disability. Diagnosing OA severity typically requires expert assessment of X-ray images and is commonly based on the Kellgren-Lawrence grading system, a…

Image and Video Processing · Electrical Eng. & Systems 2024-12-11 Nicharee Srikijkasemwat , Soumya Snigdha Kundu , Fuping Wu , Bartlomiej W. Papiez

Accurate prediction of knee osteoarthritis (KOA) progression from structural MRI has a potential to enhance disease understanding and support clinical trials. Prior art focused on manually designed imaging biomarkers, which may not fully…

Image and Video Processing · Electrical Eng. & Systems 2024-08-07 Egor Panfilov , Simo Saarakkala , Miika T. Nieminen , Aleksei Tiulpin

Knee osteoarthritis (OA) is one of the most common musculoskeletal disorders and requires early-stage diagnosis. Nowadays, the deep convolutional neural networks have achieved greatly in the computer-aided diagnosis field. However, the…

Image and Video Processing · Electrical Eng. & Systems 2020-10-13 Jiayu Huo , Liping Si , Xi Ouyang , Kai Xuan , Weiwu Yao , Zhong Xue , Qian Wang , Dinggang Shen , Lichi Zhang

This research paper explores the classification of knee osteoarthritis (OA) severity levels using advanced computer vision models and augmentation techniques. The study investigates the effectiveness of data preprocessing, including…

Knee osteoarthritis (KOA) grading based on radiographic images is a critical yet challenging task due to subtle inter-grade differences, annotation uncertainty, and the inherently ordinal nature of disease progression. Conventional deep…

Computer Vision and Pattern Recognition · Computer Science 2026-01-27 Xiaoyang Li , Runni Zhou

The diagnostic accuracy and subjectivity of existing Knee Osteoarthritis (OA) ordinal grading systems has been a subject of on-going debate and concern. Existing automated solutions are trained to emulate these imperfect systems, whilst…

Machine Learning · Computer Science 2025-05-30 Niamh Belton , Aonghus Lawlor , Kathleen M. Curran

Purpose: The aim of this study was to demonstrate the utility of unsupervised domain adaptation (UDA) in automated knee osteoarthritis (OA) phenotype classification using a small dataset (n=50). Materials and Methods: For this retrospective…

Image and Video Processing · Electrical Eng. & Systems 2023-10-31 Junru Zhong , Yongcheng Yao , Donal G. Cahill , Fan Xiao , Siyue Li , Jack Lee , Kevin Ki-Wai Ho , Michael Tim-Yun Ong , James F. Griffith , Weitian Chen

Diagnosing knee osteoarthritis (OA) early is crucial for managing symptoms and preventing further joint damage, ultimately improving patient outcomes and quality of life. In this paper, a bioimpedance-based diagnostic tool that combines…

Signal Processing · Electrical Eng. & Systems 2025-05-06 Jamal Al-Nabulsi , Mohammad Al-Sayed Ahmad , Baraa Hasaneiah , Fayhaa AlZoubi

Knee osteoarthritis (OA) is the most common musculoskeletal disorder. OA diagnosis is currently conducted by assessing symptoms and evaluating plain radiographs, but this process suffers from subjectivity. In this study, we present a new…

Computer Vision and Pattern Recognition · Computer Science 2017-10-31 Aleksei Tiulpin , Jérôme Thevenot , Esa Rahtu , Petri Lehenkari , Simo Saarakkala

This chapter presents the investigations and the results of feature learning using convolutional neural networks to automatically assess knee osteoarthritis (OA) severity and the associated clinical and diagnostic features of knee OA from…

Computer Vision and Pattern Recognition · Computer Science 2019-08-26 Joseph Antony , Kevin McGuinness , Kieran Moran , Noel E O' Connor

Knee osteoarthritis (KOA) is a degenerative joint disease that can lead to chronic pain, reduced mobility, and long-term disability. Automated severity grading from knee radiographs can support early assessment, but current methods heavily…

Computer Vision and Pattern Recognition · Computer Science 2026-04-28 Chandravardhan Singh Raghaw , Anushka Parwal , Shahid Shafi Dar , Prajakta Darade , Nagendra Kumar

Knee osteoarthritis (KOA) affects more than 600 million individuals globally and is associated with significant pain, functional impairment, and disability. While personalized multidisciplinary interventions have the potential to slow…

Artificial Intelligence · Computer Science 2025-11-26 Weizhi Liu , Xi Chen , Zekun Jiang , Liang Zhao , Kunyuan Jiang , Ruisi Tang , Li Wang , Mingke You , Hanyu Zhou , Hongyu Chen , Qiankun Xiong , Yong Nie , Kang Li , Jian Li

Osteoarthritis (OA) is a common musculoskeletal condition typically diagnosed from radiographic assessment after clinical examination. However, a visual evaluation made by a practitioner suffers from subjectivity and is highly dependent on…

Computer Vision and Pattern Recognition · Computer Science 2017-04-07 Aleksei Tiulpin , Jérôme Thevenot , Esa Rahtu , Simo Saarakkala

Knee osteoarthritis (KOA) is a disease that impairs knee function and causes pain. A radiologist reviews knee X-ray images and grades the severity level of the impairments according to the Kellgren and Lawrence grading scheme; a five-point…

Image and Video Processing · Electrical Eng. & Systems 2019-08-26 Jaynal Abedin , Joseph Antony , Kevin McGuinness , Kieran Moran , Noel E O'Connor , Dietrich Rebholz-Schuhmann , John Newell

Knee osteoarthritis (OA) is the most common musculoskeletal disease without a cure, and current treatment options are limited to symptomatic relief. Prediction of OA progression is a very challenging and timely issue, and it could, if…

Computer Vision and Pattern Recognition · Computer Science 2019-05-07 Aleksei Tiulpin , Stefan Klein , Sita M. A. Bierma-Zeinstra , Jérôme Thevenot , Esa Rahtu , Joyce van Meurs , Edwin H. G. Oei , Simo Saarakkala

Osteoarthritis (OA) is the most prevalent chronic joint disease worldwide, where knee OA takes more than 80% of commonly affected joints. Knee OA is not a curable disease yet, and it affects large columns of patients, making it costly to…

Artificial Intelligence · Computer Science 2022-12-23 Soheyla Amirian , Husam Ghazaleh , Mehdi Assefi , Hilal Maradit Kremers , Hamid R. Arabnia , Johannes F. Plate , Ahmad P. Tafti

This paper introduces a new approach to automatically quantify the severity of knee OA using X-ray images. Automatically quantifying knee OA severity involves two steps: first, automatically localizing the knee joints; next, classifying the…

Computer Vision and Pattern Recognition · Computer Science 2017-03-30 Joseph Antony , Kevin McGuinness , Kieran Moran , Noel E O'Connor

Knee osteoarthritis (OA) is the most common osteoarthritis and a leading cause of disability. Cartilage defects are regarded as major manifestations of knee OA, which are visible by magnetic resonance imaging (MRI). Thus early detection and…

Image and Video Processing · Electrical Eng. & Systems 2022-01-13 Zixu Zhuang , Liping Si , Sheng Wang , Kai Xuan , Xi Ouyang , Yiqiang Zhan , Zhong Xue , Lichi Zhang , Dinggang Shen , Weiwu Yao , Qian Wang

In medical applications, deep learning methods are built to automate diagnostic tasks. However, a clinically relevant question that practitioners usually face, is how to predict the future trajectory of a disease (prognosis). Current…

Machine Learning · Computer Science 2021-12-08 Huy Hoang Nguyen , Simo Saarakkala , Matthew B. Blaschko , Aleksei Tiulpin

This paper proposes a new approach to automatically quantify the severity of knee osteoarthritis (OA) from radiographs using deep convolutional neural networks (CNN). Clinically, knee OA severity is assessed using Kellgren \& Lawrence (KL)…

Computer Vision and Pattern Recognition · Computer Science 2016-09-09 Joseph Antony , Kevin McGuinness , Noel E O Connor , Kieran Moran