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In recent years, applications of data mining methods are become more popular in many fields of medical diagnosis and evaluations. The data mining methods are appropriate tools for discovering and extracting of available knowledge in medical…

Computational Engineering, Finance, and Science · Computer Science 2013-12-10 Peyman Mohammadi , Abdolreza Hatamlou , Mohammad Masdari

Alzheimer's disease is a progressive neurodegenerative disorder that gradually deprives the patient of cognitive function and can end in death. With the advancement of technology today, it is possible to detect Alzheimer's disease through…

Image and Video Processing · Electrical Eng. & Systems 2022-07-05 Muhammad Wildan Oktavian , Novanto Yudistira , Achmad Ridok

Parkinson's Disease (PD) is the second most common neurodegenerative disease in humans. PD is characterized by the gradual loss of dopaminergic neurons in the Substantia Nigra (SN). Counting the number of dopaminergic neurons in the SN is…

Computer Vision and Pattern Recognition · Computer Science 2023-10-16 Fatemeh Haghighi , Soumitra Ghosh , Hai Ngu , Sarah Chu , Han Lin , Mohsen Hejrati , Baris Bingol , Somaye Hashemifar

Parkinsons disease (PD) is considered one of the most frequent neurological diseases in the world. There is a need to study the early and efficient biomarkers of Parkinsons, such as changes in structural disorders like DNA and chromatin,…

Deep brain stimulation(DBS)has become an effective intervention for advanced Parkinson's disease, but the exact mechanism of DBS is still unclear. In this review, we discuss the history of DBS, the anatomy and internal architecture of the…

Neurons and Cognition · Quantitative Biology 2023-03-24 Yongtong Wu , Kejia Hu , Shenquan Liu

Accurate and interpretable gait analysis plays a crucial role in the early detection of Parkinsons disease (PD),yet most existing approaches remain limited by single-modality inputs, low robustness, and a lack of clinical transparency. This…

Computer Vision and Pattern Recognition · Computer Science 2025-12-05 Manar Alnaasan , Md Selim Sarowar , Sungho Kim

Gait analysis, an expanding research area, employs non invasive sensors and machine learning techniques for a range of applicatio ns. In this study, we concentrate on gait analysis for detecting cognitive decline in Parkinson's disease (PD)…

Signal Processing · Electrical Eng. & Systems 2023-06-13 Abdullah Alharthi

This paper focuses on the detection of Parkinson's disease based on the analysis of a patient's gait. The growing popularity and success of Transformer networks in natural language processing and image recognition motivated us to develop a…

Machine Learning · Computer Science 2022-04-04 Duc Minh Dimitri Nguyen , Mehdi Miah , Guillaume-Alexandre Bilodeau , Wassim Bouachir

Preoperative improvement rate prediction for Parkinson's disease surgery is clinically important yet difficult because imaging signals are subtle and patients are heterogeneous. We address this setting, where only information available…

Computer Vision and Pattern Recognition · Computer Science 2026-03-03 Yand Wang , Chen Zhang , Lanyun Zhu , Yixin Chen , Qunbo Wang , Yutong Bai , Jurgen Germann , Yinghong Wen , Shuai Shao

Evidence suggests Rapid-Eye-Movement (REM) Sleep Behaviour Disorder (RBD) is an early predictor of Parkinson's disease. This study proposes a fully-automated framework for RBD detection consisting of automated sleep staging followed by RBD…

Machine Learning · Computer Science 2018-11-13 Navin Cooray , Fernando Andreotti , Christine Lo , Mkael Symmonds , Michele T. M. Hu , Maarten De Vos

Alzheimer's disease (AD) is the most common neurodegenerative disease in older people. Despite considerable efforts to find a cure for AD, there is a 99.6% failure rate of clinical trials for AD drugs, likely because AD patients cannot…

Machine Learning · Computer Science 2019-03-25 Jack Albright

We present a nonlinear data-driven Model Predictive Control (MPC) algorithm for deep brain stimulation (DBS) for the treatment of Parkinson's disease (PD). Although DBS is typically implemented in open-loop, closed-loop DBS (CLDBS) uses the…

Optimization and Control · Mathematics 2025-09-09 Sebastian Steffen , Mark Cannon

Up to 90 % of patients with Parkinson's disease (PD) suffer from hypokinetic dysarthria (HD). In this work, we analysed the power of conventional speech features quantifying imprecise articulation, dysprosody, speech dysfluency and speech…

In the field of health-care and bio-medical research, understanding the relationship between the symptoms of diseases is crucial for early diagnosis and determining hidden relationships between diseases. The study aimed to understand the…

Artificial Intelligence · Computer Science 2023-02-24 Zolzaya Dashdorj , Stanislav Grigorev , Munguntsatsral Dovdondash

Parkinson's disease is a neuro-degenerative disorder affecting tens of millions of people worldwide. Lately, there has been considerable interest in systems for at-home monitoring of patients, using wearable devices which contain inertial…

Applications · Statistics 2017-02-08 Avishai Wagner , Naama Fixler , Yehezkel S. Resheff

Oculomotor alterations constitute a promising biomarker to detect and characterize Parkinson's disease (PD), even in prodromal stages. Currently, only global and simplified eye movement trajectories are employed to approximate the complex…

Computer Vision and Pattern Recognition · Computer Science 2025-02-26 Juan Niño , Luis Guayacán , Santiago Gómez , Fabio Martínez

The potential of speech as a non-invasive biomarker to assess a speaker's health has been repeatedly supported by the results of multiple works, for both physical and psychological conditions. Traditional systems for speech-based disease…

Audio and Speech Processing · Electrical Eng. & Systems 2020-06-02 Catarina Botelho , Francisco Teixeira , Thomas Rolland , Alberto Abad , Isabel Trancoso

Autism Spectrum Disorder (ASD) is one neuro developmental disorder that is now widespread in the world. ASD persists throughout the life of an individual, impacting the way they behave and communicate, resulting to notable deficits…

Computer Vision and Pattern Recognition · Computer Science 2023-03-23 Godfrin Ismail , Kenneth Chesoli , Golda Moni , Kinyua Gikunda

Alzheimer's disease (AD) is a neurodegenerative disease that affects nearly 50 million individuals across the globe and is one of the leading causes of deaths globally. It is projected that by 2050, the number of people affected by the…

Machine Learning · Computer Science 2021-10-26 Yash Kumar , Piyush Maheshwari , Shreyansh Joshi , Veeky Baths

Parkinson's disease (PD), a prevalent neurodegenerative disorder, significantly affects patients' daily functioning and social interactions. To facilitate a more efficient and accessible diagnostic approach for PD, we propose a dynamic…

Computer Vision and Pattern Recognition · Computer Science 2025-12-11 Xiaochen Huang , Xiaochen Bi , Cuihua Lv , Xin Wang , Haoyan Zhang , Wenjing Jiang , Xin Ma , Yibin Li
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